With Jabari Parker having recovered from his recent slump, Duke has gotten on a roll following a rough start in ACC play.
A fourth straight league victory would put coach Mike Krzyzewski in yet another exclusive club.
The 18th-ranked Blue Devils will try to extend the nation's longest home winning streak Saturday when they take on a Florida State team that has won three of the last five meetings.
Parker has used his size and strength to get back on track after averaging 10.8 points - far below his season average of 18.9 - while shooting 32.2 percent from the field over a five-game stretch.
The freshman forward shot a combined 21 3-point attempts and averaged 6.0 rebounds during that span, but has attempted only five 3s while totaling 40 points and 22 boards to help Duke (15-4, 4-2) win its last two by a combined 56 points.
Parker scored 17 to go with a season-best 15 rebounds to lead the Blue Devils to Wednesday's 67-46 victory at Miami, their third straight ACC win after a 1-2 start in the conference.
''He's a long way from dominating,'' Krzyzewski said. ''He's in a process of getting better. The potential is there to be an outstanding player, and he was really good.''
Parker had six of the team's 15 offensive rebounds as the Blue Devils outscored Miami 22-7 on second-chance points.
That could be a key as they look to extend their nation-best 27-game home winning streak. The Seminoles (13-5, 4-2) rank ninth nationally with a 37.6 defensive field-goal percentage, but have given up an ACC-worst 13.7 offensive rebounds per game.
Another victory at Cameron Indoor Stadium would put Krzyzewski along side Syracuse's Jim Boeheim (936) as the only two coaches with at least 900 wins at one school. Krzyzewski already owns the overall NCAA Division I record with 972.
The Blue Devils have won by an average of 20.6 points at home while holding six straight opponents to fewer than 70 points.
They'll try to continue that trend against Florida State, which ranks third among ACC teams with a 47.9 field-goal percentage and a 37.0 3-point shooting.
The Seminoles are coming off one of their best offensive performances, hitting 58.0 percent from the field - including 8 of 16 from long range - in a 76-74 win over visiting Notre Dame on Tuesday.
Ian Miller hit a floater in the lane with four seconds remaining to seal their eighth win in 10 games.
Aaron Thomas scored 20 in his first start in place of Okaro White, who added 12 points and 11 rebounds off the bench. White could return to the starting lineup after he was reprimanded by the ACC for conduct at the end of a 78-66 loss at Virginia last Saturday.
Florida State had won three of four in this series before a 79-60 loss in Tallahassee on Feb. 2. Quinn Cook had 18 points and Rasheed Sulaimon added 14 for the Blue Devils, while Thomas led the Seminoles with 14.
In the most recent meeting in Durham, Florida State sank a 3-pointer as time expired for a 76-73 victory over then-No. 4 Duke on Jan. 21, 2012.
"Coach (Leonard Hamilton) doesn't even have to say anything to us before we play there because of the history and the respect that they have from the country," said guard Devon Bookert, who is 11 of 15 from 3 in his last four games.
The Seminoles have beaten then-No. 10 VCU and then-No. 22 Massachusetts this season, and lost to then-No. 14 Michigan and then-No. 15 Florida by a total of three points.