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| Team Ranking | PTS/G | OPP PTS/G |
| Big 12 Conference | 66.7 (8th) | 67.0 (8th) |
| Division 1 | 94th | 79th |
| = Home Games |
| Complete schedule | |||
| Regular Season | |||
| Date | Opponent | Result / Time | Record |
| Nov 11 | Texas A&M-CC | Won 71-39 | 1-0 |
| Nov 15 | Ark.-Pine Bluff | Won 73-46 | 2-0 |
| Nov 16 | UT-San Antonio | Won 90-85 | 3-0 |
| Nov 23 | Stanford | Lost 67-82 | 3-1 |
| Nov 25 | Virginia Tech | Lost 57-59 | 3-2 |
| Nov 30 | Tulsa | Won 59-56 | 4-2 |
| Dec 4 | Langston | Won 80-58 | 5-2 |
| Dec 7 | @Missouri St. | Won 72-67 | 6-2 |
| Dec 10 | Pittsburgh | Lost 68-74 | 6-3 |
| Dec 17 | New Mexico | Lost 56-66 | 6-4 |
| Dec 21 | @Alabama | Lost 52-69 | 6-5 |
| Dec 28 | SMU | Won 68-58 | 7-5 |
| Dec 31 | Virginia Tech | Lost 61-67 | 7-6 |
| Jan 4 | Texas Tech | Won 67-59 | 8-6 (1-0) |
| Jan 7 | @Texas | Lost 49-58 | 8-7 (1-1) |
| Jan 9 | Oklahoma | Won 72-65 | 9-7 (2-1) |
| Jan 14 | @Baylor | Lost 65-106 | 9-8 (2-2) |
| Jan 18 | @Iowa St. | Lost 68-71 | 9-9 (2-3) |
| Jan 21 | Kansas St. | Lost 58-66 | 9-10 (2-4) |
| Jan 25 | Missouri | Won 79-72 | 10-10 (3-4) |
| Jan 28 | @Texas A&M | Lost 61-76 | 10-11 (3-5) |
| Jan 31 | @Texas Tech | Won 80-63 | 11-11 (4-5) |
| Feb 4 | Baylor | Lost 60-64 | 11-12 (4-6) |
| Feb 7 | Iowa St. | Won 69-67 | 12-12 (5-6) |
| Feb 11 | @Kansas | Lost 66-81 | 12-13 (5-7) |
| Feb 15 | @Missouri | 9:00 PM | |
| Feb 18 | Texas | 4:00 PM | |
| Feb 22 | @Oklahoma | 8:00 PM | |
| Feb 25 | Texas A&M | 2:00 PM | |
| Feb 27 | Kansas | 9:00 PM | |
| Mar 3 | @Kansas St. | 1:45 PM | |
| TEXAS vs. OKLAHOMA STATE February 18, 2012 3:30 PM ET | |
| TEXAS vs. OKLAHOMA STATE February 18, 2012 3:00 PM ET | |
| OKLAHOMA STATE vs. MISSOURI February 15, 2012 8:30 PM ET | |
| OKLAHOMA STATE vs. MISSOURI February 15, 2012 8:00 PM ET | |
| OKLAHOMA STATE vs. KANSAS February 11, 2012 3:00 PM ET | |
| OKLAHOMA STATE vs. KANSAS February 11, 2012 2:30 PM ET | |
| IOWA STATE vs. OKLAHOMA STATE February 7, 2012 6:00 PM ET | |
| Cowboy Basketball February 7, 2012 3:00 AM ET | |
| BAYLOR vs. OKLAHOMA STATE February 4, 2012 1:15 PM ET | |
| BAYLOR vs. OKLAHOMA STATE February 4, 2012 12:30 PM ET | |
| OKLAHOMA STATE vs. TEXAS TECH January 31, 2012 7:30 PM ET | |
| OKLAHOMA STATE vs. TEXAS TECH January 31, 2012 7:00 PM ET | |
| OKLAHOMA STATE vs. TEXAS A&M January 28, 2012 3:00 PM ET | |
| MISSOURI vs. OKLAHOMA STATE January 25, 2012 7:00 PM ET | |
| MISSOURI vs. OKLAHOMA STATE January 25, 2012 6:30 PM ET | |
| Cowboy Basketball January 25, 2012 3:00 AM ET | |
| On Demand: MBB at OSU January 21, 2012 1:30 PM ET | |
| KANSAS STATE vs. OKLAHOMA STATE January 21, 2012 12:30 PM ET | |
| KANSAS STATE vs. OKLAHOMA STATE January 21, 2012 12:30 PM ET | |
| OKLAHOMA STATE vs. IOWA STATE January 18, 2012 8:00 PM ET | |
| OKLAHOMA STATE vs. BAYLOR January 14, 2012 3:00 PM ET | |
| OKLAHOMA STATE vs. BAYLOR January 14, 2012 2:30 PM ET | |
| OKLAHOMA STATE vs. BAYLOR January 14, 2012 2:00 PM ET | |
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