Whigham left the field on a stretcher and was held overnight at Tallahassee Memorial Hospital after a collision in the back of the end zone during the game.
According to a school release, Whigham suffered a "lung contusion and possible tearing of scar tissue from a prior surgical history for achalasia." Apparently Whigham's battle with achalasia, a rare esophageal disorder, prevented him from eating solid foods for months while in high school.
Whigham's status for the remainder of the 2013 football season will be evaluated.
"I'm not really worried about when he gets back," Shafer said Monday. "I just can't wait to see the whites of his eyes and move forward."
That was not the only injury issue for Syracuse in the loss. Running back Prince-Tyson Gulley (ankle) and wide receiver Jarrod West (upper body) left the game early and will have their status updated later this week.
Syracuse hosts Pittsburgh in a battle of ACC newcomers on Saturday. Both teams are 5-5, fighting for bowl eligibility down the stretch of the conference season. If the Orange fall Saturday, there will one more opportunity against Boston College in the Carrier Dome on Nov. 30.