Blake Bortles, QB, UCF (vs. South Florida): Bortles is on the verge of leading Central Florida to a BCS bowl, and so far he has thrown 20 touchdowns passes to five interceptions, with three rushing scores, as well. He had a couple surprising off nights, but that is unlikely to happen against South Florida. This is a very favorable matchup, and Bortles should take advantage.
Sean Schroeder, QB, Hawaii (vs. Army): This is Hawaii's last chance to win a game, and Schroeder is coming off a great game. Against Wyoming, he threw for 499 yards, six touchdowns and an interception. He has been better at home, and Army is one of Hawaii's weaker opponents. Hawaii's offense should be going all out in this one, and Schroeder will be at the center of that. Another big game, and perhaps a victory, could be in the works.
Taylor Kelly, QB, Arizona State (vs. Arizona): Kelly has been impressive throwing the ball, as he has tallied 3,063 passing yards with 25 touchdowns to 10 interceptions. However, he's also excelled on the ground, rushing for 411 yards and eight scores. Arizona was impressive against Oregon in its upset last week, but that isn't likely to happen again. The Sun Devils should be able to keep their high-powered offense firing, and Kelly will rack up the Fantasy points.
Jahwan Edwards, RB, Ball State (vs. Miami (OH): While Edwards has cooled after three consecutive three-touchdown games earlier this season, he has still been very good. Even last week against Northern Illinois, he rushed for 156 yards and a touchdown. Now he gets to run against winless Miami of Ohio. This is a much easier matchup. Edwards should tear it up on the ground.
Jeremy Hill, RB, LSU (vs. Arkansas): While LSU has a rotation of talented running backs, Hill is the primary, and best, of the bunch. He has rushed 155 times for 1,040 yards and 13 touchdowns, and that's against an SEC schedule. LSU end its season against a struggling Arkansas team, and it should not be able to stop Hill. Other players will get carries, but there should be enough Fantasy value to go around in this one.
Tim Cornett, RB, UNLV (vs. SDSU): Cornett has 15 touchdowns this season, four of which came last week against Air Force, when he also rushed for 220 yards on 36 carries. He's had several big games this year, and he could certainly do that against San Diego State. Cornett has the chance to end the regular season on a high note and against the Aztecs the chances are good he will have another impressive performance.
Austin Franklin, WR, NMSU (vs. Idaho): Franklin was ineligible for the first four games of the season, and after a slow start to his return he had four good games in a row, including huge efforts against Louisiana-Lafayette and Boston College. Franklin was very good last year, and now that he's back, he's the clear top weapon on NMSU's offense. The Aggies play host to another lowly WAC orphan, Idaho, this week. Franklin should put up huge numbers versus the Vandals.
Cody Latimer, WR, Indiana (vs. Purdue): The Hoosiers aren't going to a bowl this year, but they get the chance to end the season on a high note with a lousy Purdue team on the docket. Latimer is closing in on 1,000 yards, and he posted strong Fantasy numbers before visiting Wisconsin and Ohio State the last two weeks. With a significantly easier opponent this week, Latimer should return to his earlier season form.
Josh Huff, WR, Oregon (vs. Oregon State): After losing to Arizona and kissing their Pac-12 title hopes goodbye, Oregon gets the chance to take out its frustrations on intrastate-rival Oregon State. The Beavers defense has not put up much of a fight this season, and the Ducks should score in bunches, per usual. Huff has been their top receiver, with 850 yards and eight touchdowns. He will add to that in this game, perhaps significantly so.
Tajh Boyd, QB, Clemson (at South Carolina): Last week, Boyd took advantage of The Citadel, throwing five touchdowns passes. Hopefully he had fun, because now he has to visit South Carolina. Boyd is a very good quarterback, and the Gamecocks likely won't shut him down completely. However, this is the first tough defense he will face on the road this year, so don't expect his usual output.
Brett Hundley, QB, UCLA (at USC): Throughout this season, Hundley has shown the tendency to be held in check whenever he has faced a more formidable opponent. Even teams such as Washington and Arizona State limited his numbers, and those games were at home. Now Hundley has to face crosstown-rival USC on the road. Since Ed Orgeron took over as head coach, the Trojans have been much improved. It seems likely Hundley will struggle once more.
Tommy Rees, QB, Notre Dame (at Stanford): In his last three games, Rees has thrown as many interceptions as touchdowns, and he hasn't thrown more than two touchdowns in any of those games either. In seven of his last eight games, he hasn't thrown for more than 284 yards, as well. Oh, and Notre Dame is on the road against Stanford. That alone is enough to make Rees' stock plummet. Everything else just solidifies that presumption.
Tre Mason, RB, Auburn (vs. Alabama): Auburn is the second best running team in FBS, and Mason is the lead running back. In addition to his 1,153 yards rushing, he has a whopping 17 touchdowns. He has scored in all but one game, but in that game Mississippi State held him to 34 yards in addition to keeping him out of the end zone. Alabama has an even tougher defense, and it is definitely the stoutest defense Auburn has faced all season. The Tigers will definitely give Mason the ball plenty, but the Crimson Tide should keep him in check.
Todd Gurley, RB, Georgia (at Georgia Tech): Gurley has played well when healthy, which, unfortunately for Georgia, hasn't been all that often. He's contributed on the ground and through the air. However, he's also pretty much the only man left standing. Now that Aaron Murray is out, Georgia Tech will be able to focus entirely on stopping Gurley. The Yellow Jackets should be able to do that to some degree, enough to limit Gurley's Fantasy numbers. Better options likely are available.
David Cobb, RB, Minnesota (at Michigan State): Cobb has run well since emerging as Minnesota's top running back, and on the season he has 1,010 yards rushing and seven touchdowns. He had four games in a row with more than 100 yards before last week when he was held to 68 yards by Wisconsin. Well, a road game against Michigan State is even more difficult a task than rushing against the Badgers. Cobb will struggle to get much done against the Spartans.
Ryan Grant, WR, Tulane (at Rice): Grant was having a good season until quarterback Nick Montana struggled after returning from injury. That led to two poor games, before last week he finally found success again with 104 yards and two touchdowns. That said, those numbers were put up against UTEP, which is awful. Rice is a much tougher opponent, and if Montana has any issues again, Grant will be in a tough situation once more.
Jeremy Johnson, WR, SMU (at Houston): Johnson has 100 catches through 10 games and has gone for 1,007 yards and six touchdowns. However, quarterback Garrett Gilbert hurt his knee last week, and he may not be able to play this week. If that's the case, that would likely hinder Johnson's Fantasy potential. Plus, Houston has been pretty good on defense, and Johnson has actually only scored in three games this year. Playing Johnson this week is too risky.
Quinshad Davis, WR, North Carolina (vs. Duke) Last week, North Carolina put up a whopping 80 points, but that was against Old Dominion. Now the Tar Heels play Duke, a much tougher opponent, and one that has had some good defensive performances. Davis has nine touchdowns, but he only has 692 yards this season. With a backup quarterback under center as well, expect Davis to be limited this week.