It appears likely that Patriots quarterback Tom Brady will be suspended for the first four games of the season after his request for a rehearing before a full panel of judges was denied by the Second Circuit on Wednesday. His only recourse remaining is through the United States Supreme Court.

We'll see how that process goes, but Fantasy owners should be prepared to be without Brady to start the season, which clearly has an impact on the entire offense. But it doesn't mean you should panic with the Patriots.

Brady should still be drafted as a No. 1 Fantasy quarterback with a mid-round pick. You won't have him for the first four games of the season (at ARI, vs. MIA. vs. HOU and vs. BUF), but he averaged 26 Fantasy points a game last year in a standard league. He'll definitely win you some games from Week 5 on, and he's worth the headache of dealing with the suspension.

The good news is quarterback is deep for owners in 14-team leagues and smaller, so you should find a capable replacement and not have to rely on New England backup Jimmy Garoppolo. My colleague, Dave Richard, wrote about several quarterbacks you can target to replace Brady for the four games he'll miss, and I would also include Tony Romo for owners in 10-team leagues, as well as Kirk Cousins and Joe Flacco in deeper formats.

Aside from Brady, the two big Fantasy options most people ask about are Rob Gronkowski and Julian Edelman. Gronkowski should still be considered a first-round pick in all leagues, and it's hard to imagine him being awful with Garoppolo.

A good comparison for Gronkowski in the four games without Brady is how he performed to start the 2014 season when he coming off an injury-shortened year in 2013. He averaged eight Fantasy points a game in standard leagues over the first four games that year, including three touchdowns over that span, and finished the season with at least nine Fantasy points in nine of his final 11 outings.

If you recall that season, Brady was terrible to start the year, but he took off with huge stats from Week 5 on. Now, Gronkowski has some concerns this year with Brady out, the additions of Martellus Bennett and Chris Hogan and a potential challenger to his throne as the No. 1 tight end in Jordan Reed. But I still expect Gronkowski to dominate all tight ends, and he should be fine without Brady.

As for Edelman, he's a little more of a risk since he's coming off a second foot surgery this offseason. He should be fine for Week 1, but his health should be monitored throughout training camp. He's still the No. 2 target in the passing game, but he'll lose production to Hogan and Bennett, which slightly lowers his value.

His Average Draft Position is toward the end of Round 4, which is fine for PPR leagues, but I'd rather wait until Round 5 or later in standard formats. And I like drafting Hogan with a late-round pick in all leagues since I expect him to play well with his move from Buffalo to New England.

It's not a bad idea to take a flier on Bennett with a late-round pick, and the running backs should be fine with or without Brady. Dion Lewis is worth drafting in Round 4 in PPR and Round 5 in standard leagues, and LeGarrette Blount is worth a late-round pick in all formats.

Now, let's get to this week's #fantasymail, and remember you can submit your questions to me on Twitter @jameyeisenberg or on my Facebook page. Please use that hashtag when sending in your questions.

This week, we'll cover the following topics:

  • What rounds to target Doug Martin and Mike Evans?
  • Kelvin Benjamin vs. Sammy Watkins in dynasty
  • DeVante Parker vs. Donte Moncrief as a keeper
  • Odell Beckham vs. Adrian Peterson as a keeper
  • Can last year's injured receivers bounce back?
  • Le'Veon Bell vs. Evans as a keeper

From Twitter ...

I'm excited about Evans this season, and he should be a third-year breakout receiver. He spent time this offseason working out with Jameis Winston to help improve their rapport, and it should pay off in a big way. Evans is worth drafting in Round 2 in the majority of leagues. Martin should play well, but I'm concerned about his outlook following his contract extension this offseason. I would only draft Martin in Round 3, and he should be handcuffed with Charles Sims, who is worth drafting with a mid-round pick. Sims, Vincent Jackson and maybe Austin Seferian-Jenkins will get drafted, and Winston is a great quarterback to wait on with a late-round pick. I like Winston as a top-12 quarterback this year.

If this were a re-draft league, I would take Benjamin because I have more faith in him with Watkins coming off foot surgery this offseason. But long-term, I still expect Watkins to have the better career, and he's the better investment on Draft Day in a dynasty league. When healthy, Watkins should have the higher ceiling, and hopefully Buffalo pairs him with Tyrod Taylor for years to come because we saw the two play well in 2015. Benjamin is just a notch behind Watkins in dynasty leagues, and it wouldn't be a surprise if he had the better career -- thanks to Cam Newton. But for now, the pick is Watkins.

Winston has the chance for a big year and is great value in Round 16, but you also have tremendous value with Parker and Moncrief. I like Parker slightly better since he'll be the No. 1 receiver for new coach Adam Gase, which has led to good things in the past (see Demaryius Thomas, Brandon Marshall and Brandon Lloyd). And Moncrief was playing at a high level in 2015 before Andrew Luck got hurt, so hopefully they will pick up where last season ended. Moncrief is also entering his third year in the NFL, which could lead to a breakout campaign.

I hope Peterson is dominant again in 2016, but he makes me nervous at 31 and having played at least eight full seasons in the NFL. It's a different discussion when talking about him as a keeper vs. drafting him in the top-five overall picks, but I wouldn't consider him over Beckham. I expect Beckham to again be a dominant receiver, and he might even improve in his third season. Beckham is the easy choice here, and then you can potentially draft Peterson again in the first round.

From Facebook ...

All Fantasy owners should be excited about the healthy return of Jordy Nelson, Keenan Allen and Benjamin. Nelson should continue to be the Packers' No. 1 receiver, which makes him a No. 1 Fantasy option worth drafting by Round 2 in all leagues. He will make Aaron Rodgers and Randall Cobb better, and this entire offense should be dominant. Allen is also worth drafting by Round 3, and he will help Philip Rivers play like a top-10 Fantasy quarterback. Benjamin should be drafted by Round 5, and he will replace Ted Ginn as the No. 1 receiver for the Panthers. Ginn scored 10 touchdowns last year, and Benjamin is clearly the better talent. He will also help Newton, and it's good to have all three of these receivers back on the field.

It's hard to pass on Bell in the second round since you can make a strong case he should be the No. 1 overall pick this year, but it's difficult to give up on Evans at that value. To start your team with Beckham and Evans in a PPR league and still have your first 12 picks is incredible, and you can now load up on running backs early and often. Maybe you get lucky and someone like Ezekiel Elliott or Lamar Miller falls to you at No. 9, and that's an amazing trio of players to start your team.