Guy suffered a Grade One hamstring injury in Sunday's loss to Houston. Guy had two tackles in the loss. It's not clear if he'll be able for a special teams role again this week.
The Colts have signed Winston Guy and released Rob Ruggiero from the practice squad. Guy had been with the Jaguars earlier this season, but was waived from the practice squad in late September. Ruggiero had not appeared in a game with the Colts this year.
The Jaguars promoted safety Craig Loston from the practice squad and waived safety Winston Guy.
The Jaguars have made two changes to their starting lineup on defense heading into Week 4 at San Diego, according to The Florida Times-Union. Josh Evans has supplanted Winston Guy as the starting free safety, and J.T. Thomas takes over for LaRoy Reynolds as the starting outside linebacker.
Jaguars safety Winston Guy is dealing with cramping Week 3. Guy is considered questionable to return. He came into the game probable due to an illness. He notched two tackles before leaving.