Bears over Colts: The Bears are at home with Jay Cutler and Brandon Marshall back together. Indy will win games this year with Andrew Luck, but not this one because no one on the Colts can block Julius Peppers.
Bills over Jets: Buffalo gets three points and they have a pass rush that the Jets can't block. Buffalo picked off then-Broncos QB Tim Tebow three times last season -- so keep that in mind if he is in the Jets' wildcat.
Saints over Redskins: The emotion and noise in the Superdome are too much for rookie QB Robert Griffin III, who will be trying to keep up with Drew Brees and an offense that averages nearly 40 points a game at home.