UPDATE: Jed Lowrie broke up the no-hitter with one out in the seventh inning, singling to right off Downs. Downs walked Kevin Youkilis to start the inning, then got David Ortiz looking.
In the top of the seventh, Vernon Wells hit a two-run homer to give Anaheim a 2-0 lead.
A two-and-a-half hour rain delay and change of pitchers hasn't helped Boston's bats -- as the Angels have a combined no-hitter through six innings.
Starter Ervin Santana didn't allow a hit in the first four innings, striking out seven Red Sox batters in four innings before the rain delay at Fenway Park. Rich Thompson replaced Santana after the delay and held the Red Sox hitless for another 1 2/3 innings.
Dan Wheeler has entered the game for the Red Sox in the seventh with the game tied 0-0.For more baseball news, rumors and analysis, follow @cbssportsmlb on Twitter or subscribe to the RSS feed.