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Chicago at Kansas City

Venue: Kauffman Stadium

The last thing the Chicago White Sox need right now is a matchup with Kansas City Royals starter Jeremy Guthrie.

The right-hander has completely shut down Chicago since being acquired by the Royals last summer, and he'll look to add to the visiting White Sox's woes in the opener of a three-game series Friday night.

Guthrie came to Kansas City in a deal for left-hander Jonathan Sanchez on July 19, and he's gone 3-0 with a 0.40 ERA in six starts against the White Sox. The Royals have won all six games, and Guthrie has allowed one run over 15 innings in winning both outings this season.

He pitched a four-hitter in his first career shutout in the last matchup May 4, walking one in a 2-0 victory in Kansas City.

"He's been tough on us," White Sox manager Robin Ventura said. "First, because he's good. ... He seems to pick it up when we're facing him. ... You have to pick your poison, you go after him early and then you pop it up. He's tough."

Guthrie beat Baltimore in his next start May 9 to increase his club record to 18 consecutive outings without a defeat and improve to 5-0 with a 2.28 ERA on the season. However, he's struggled since, going 2-4 with a 5.24 ERA in his past seven starts.

Guthrie (7-4, 3.72 ERA) gave up three home runs in a 5-3 loss at Tampa Bay on Saturday and leads the majors with 19 allowed.

"I'd like someone to pass me," Guthrie told the Royals' official website. "It's hard for them to pass me, I'm going real fast."

Guthrie has not allowed a home run in 44 2-3 innings against the White Sox (29-41) since joining the Royals (34-36).

Paul Konerko and Adam Dunn hit back-to-back homers in Minnesota on Thursday, but it wasn't enough as the White Sox lost 8-4.

Chicago has dropped three straight, seven of eight and 17 of 22 games. The White Sox are 12 games under .500 for the first time since the last day of the 2007 season.

"We truly feel like we're way too good to be playing like this," pitcher John Danks said. "We feel we're just as talented as any team in the league."

The Royals are 12-6 in June but have lost two in a row, falling 6-3 in Cleveland on Wednesday night.

"It's tough," left fielder Alex Gordon said. "... We would have loved to turn these last two games around. We could have. We had our opportunities and just didn't do it."

Kansas City will be facing Hector Santiago (2-5, 3.30), who has been filling in for the injured Jake Peavy. The left-hander has been in and out of the rotation this season, going 2-3 with a 3.00 ERA in seven starts.

He lost 5-4 in Houston on Sunday after giving up three runs in the second inning.

"Like I said earlier in the year, it's always one inning," Santiago told the White Sox's official website. "First, second inning I get in trouble and then I settled in, but I have to get to the point where I get through the first two innings. Get through those and it seems like we're good from there."

Santiago has not allowed a run while striking out 13 in 11 1-3 career innings against the Royals. He's made one start, allowing three hits in four innings opposite Guthrie on Sept. 9 when the Royals won 2-1 in 10 innings in Chicago.

Copyright 2014 by STATS LLC. Any commercial use or distribution without the express written consent of STATS LLC is strictly prohibited.
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Probable Starters

Hector Santiago, LHP
2013 stats
57.1 Innings Pitched 92.0
2-5 Wins-Losses 7-4
3.30 Earned Run Average 3.72
30 Walks 31
60 Strikeouts 44
103 Pitches Per Start 103
Career vs. opponent
11.1 Innings Pitched 112.1
0-0 Wins-Losses 6-5
0.00 Earned Run Average 2.88

Jeremy Guthrie, RHP
weather image  Partly sunny. Warm.
Hi TempLo TempWindHumidityPrecip %
TeamStandingsWLPct.GBL 10Strk
Chi White Sox4th AL Central7284.462146-4 W 2
Kansas City2nd AL Central8571.54515-5 W 1
vs Jeremy Guthrie
De Aza176002.353
vs Hector Santiago
Chi White Sox
N. JonesElbow
F. PaulinoShoulder
Kansas City
L. HochevarElbow
Series Game Log
Apr 21CLECLE 4-3McAllister Guthrie 
Apr 22CLEKC 8-2Shields Salazar 
Apr 23CLECLE 5-3Shaw Herrera 
Apr 24CLECLE 5-1Kluber Chen 
Jun 10KCKC 9-5Vargas Kluber 
Jun 11KCKC 4-1Ventura Bauer 
Jul 4CLEKC 7-1Ventura Tomlin 
Jul 5CLECLE 7-3House Guthrie 
Jul 6CLECLE 4-1Kluber Duffy 
Jul 24KCKC 2-1Crow Rzepczynski 
Jul 25KCKC 6-4Herrera Carrasco 
Jul 26KCKC 7-5Guthrie McAllister 
Jul 27KCCLE 10-3Salazar Chen 
Aug 29KCCLE 6-1Salazar Vargas 
Aug 30KCCLE 3-2Tomlin Downs 
Aug 31KCPPD   
Sep 22KCCLE 4-3Allen Holland 
Sep 22CLEKC 2-0Duffy Carrasco 
Sep 23CLE 7:05 PM EDT  
Sep 24CLE 7:05 PM EDT