Jorge Cantu homered with one out in the bottom of the ninth inning to give the last-place Devil Rays a 7-6 victory Tuesday night, their second in as many days over the team with baseball's best record.
"The baseball is not bouncing our way right now. Hopefully that will change," White Sox manager Ozzie Guillen said after watching his pitchers give up three walks, five hits and seven RBIs to the bottom three hitters in Tampa Bay's lineup.
"That's going to happen to the best teams in baseball," Guillen added. "Don't think we're that good."
The Devil Rays rallied twice to tie the game before Cantu's walkoff homer on a 1-0 pitch from Shingo Takatsu (0-2). The third baseman had tied it 6-all with an RBI single off Luis Vizcaino in the seventh.
Cantu's 402-foot shot into the stands in left was the major league-high ninth homer by the No. 9 spot in the Devil Rays' order. He went 3-for-4 with two RBI, boosting the team's average in that spot to .367.
"I was just up there hacking," said Cantu, adding that his homer was a gift for his mother on Mexican Mother's Day.
"I said: 'You know what, I'm going to hit one for you.' I tried my best, and look. It can't get any better than that."
Jesus Colome (1-0), who came off the 15-day disabled list earlier Tuesday, pitched one perfect inning for the victory as Tampa Bay became just the second team to take a series from the White Sox this season.
Despite losing for the second straight day after an eight-game winning streak, the White Sox still have the major league's best record (24-9).
"We beat ourselves. ... Walks will always give you trouble at the big league level," Guillen said. "Their team can hit. If you keep those kids in the game, they're going to come back."
A lack of hitting with runners in scoring position has dogged the Devil Rays all season. They were 3-for-14 in those situations Tuesday night and are just 1-for-21 with the bases loaded this season.
The White Sox scored two runs in the fourth off Devil Rays starter Mark Hendrickson on consecutive doubles by Juan Uribe, Chris Widger and Crede -- Chicago's seventh, eighth and ninth hitters who went 7-for-11 with five doubles and three RBI.
The 4-1 lead was short-lived, though, with Hall delivering his homer after Chicago starter Jose Contreras walked Nick Green and Singleton to open the fourth. Overall, the White Sox walked nine.
"That's where I lost the game," Contreras said through an interpreter. "I opened the inning with two walks, and then came the big hit. That's where I lost the game -- walking people."
Hendrickson allowed six runs and eight hits in six innings. His throwing error on Crede's infield single allowed Widger to score and snap a 4-4 tie and enabled Crede to race all the way to third base.
Two batters later, Tadahito Iguchi laid down a perfect squeeze bunt with Crede sprinting to the plate to make it 6-4.
The Devil Rays rallied again with two runs in the seventh on a groundout by Singleton and Cantu's two-out RBI-single.
Contreras allowed four runs and five hits in five-plus innings.
- The White Sox have led in all 33 of their games, a major league record to begin a season.
- The Devil Rays activated Colome before the game and optioned OF Jonny Gomes to Triple-A Durham.
- Contreras allowed a homer with a runner on for the first time in his last 13 starts.
- Huff hasn't homered since April 18, a stretch of 20 games.