Escobar was supposed to start against Jon Garland on Thursday, but the game was rained out. No makeup date was announced, and the teams are not scheduled to meet again until a three-game series in Anaheim in September.
Instead, Escobar will face Seattle on Friday. On their website, the White Sox listed Garland as a probable for Friday night's game at Minnesota.
Escobar was pitching when A.J. Pierzynski reached first on a disputed third strike in the ninth inning of Game 2 of the ALCS last season. Pinch-runner Pablo Ozuna eventually scored the winning run to even the series. The White Sox won the series in five games and went on to win their first World Series since 1917.
On April 29, the White Sox accused Escobar of deliberately hitting Pierzynski in the knee, something the pitcher denied. Although he reiterated the accusation on Wednesday, White Sox manager Ozzie Guillen told reporters his team would not retaliate.
"My situation is I don't come here to hit people," Guillen said. "I come here to win games, and my team's doing it."
At 23-10, they've been doing more of it than any other team.
The Angels (15-20), meanwhile, are struggling. Wednesday's 12-5 victory was just their third in 13 games.
Chicago took a calculated risk and had knuckleballer Charlie Haeger start for the injured Jose Contreras, rather than rush Brandon McCarthy out of the bullpen. Haeger was wild in his major league debut, walking six and allowing six runs (five earned) in 4 1/3 innings and was sent back to Triple-A after the game. McCarthy allowed two runs in four innings of relief and earned a start Monday at Minnesota.
He left after allowing a one-out double by Orlando Cabrera in the ninth and intentionally walking Vladimir Guerrero. Both runners scored during a six-run outburst by the Angels.
"This kid is throwing the ball good," Guillen said. "(The) last couple outings he's thrown the ball outstanding -- one reason we're giving him the shot to start."
McCarthy started 10 games last year, but he had not pitched more than three innings this season. Wednesday's outing eased concerns about his stamina.
"We stretched Mac, and we'll work all week to get him ready for the next game," Guillen said.