Cuddyer's heads-up play tied the score in the eighth inning and the Twins went on to their 11th straight win, 6-5 over the Kansas City Royals on Monday night.
With two outs and the Twins trailing by a run, Cuddyer broke for third on a pitch in the dirt and scored the tying run on Buck's throwing error.
"I saw his glove that he was going throw a split and I anticipated it going in the dirt," Cuddyer said. "It didn't kick as far as I thought it was going to kick, but I had already committed myself, just run, hope for the best, hopefully put some pressure on them and he made a bad throw.
"We put pressure on them from the get-go and had aggressive baserunning. Tonight it so happened we were able to use that to come back with. It took everybody to win. If Morneau doesn't get that big hit, we can't be aggressive on the base paths."
Morneau, who drove in three runs, singled home Luis Castillo for the first run. Morneau scored the go-ahead run on Burgos' second wild pitch of the inning.
"Don't ask how you win it, just win it," Twins manager Ron Gardenhire said. "We got fortunate. It wasn't the prettiest thing in the world, but it was a win."
Andrew Sisco (0-2), the third of four Kansas City pitchers in the eighth, was charged with the loss. Burgos blew his eighth save in 21 opportunities.
"I'm disappointed to play like we did," Royals manager Buddy Bell said. "We gave them about five outs, which you can't do. Our bullpen has been doing a good job, but tonight wasn't one of those nights."
The Twins have won 19 of 20 and 21 of 23. They picked up a game in the AL Central on Detroit and Chicago, both who lost Monday.
"I wouldn't say we're invincible, but we feel good about ourselves, obviously" Cuddyer said. "We feel confident. We feel like when we go out there that we've got that confidence to win."
Mauer, who leads the majors with a .391 average, homered on an 0-2 pitch from Scott Elarton leading off the sixth. Mauer's home run, his sixth, landed in the Twins' bullpen in left.
Morneau, who stretched his hitting streak to 11 games to match his career best, hit his 22nd home run with Cuddyer aboard in the second. Morneau has five home runs and 14 RBI in his hitting streak. Morneau also had a run-scoring single in the eighth.
Berroa was hitting .143 in his previous 13 games and had one extra base hit since June 4, a span on 23 games, before the bases-clearing double.
Elarton allowed four runs and six hits over seven innings, while walking three and striking out one.
Santana, who gave up just five earned runs in going 5-0 in June and was selected AL pitcher of the month, allowed five runs, four earned, in 5 2/3 innings. He gave up six hits, walked three and hit a batter. Santana struck out seven, running his major league-leading total to 131.
"It is not about just one guy," Santana said. "Tonight I failed to do my job, but the team picked me up big time and we won the game. It doesn't matter how you win the game, as long as you win the game. We had some rain, the field was wet and it was hot, too. One bad pitch -- I don't even say it was a bad pitch -- it was good hitting. We threw Berroa back-to-back-to-back changeups and the last one he was able to put in play and got three RBI."
Said Mauer, "Santana didn't have his best stuff, but he battled through. He wasn't terrible. They hit a couple of good pitches. He didn't have his normal stuff. When that happens, everybody thinks that something is wrong, but there is not."
David DeJesus singled to lead off the third and doubled in the seventh, extending his hitting streak to 10 games, the longest by a Royal this season.
- The Royals completed interleague play with a 10-8 record, their most victories in a season against National League opponents.
- Kansas City LHP Jimmy Gobble makes his second start of the season on Tuesday. His first was May 24, a loss to Detroit.
- This is the Twins' longest streak since winning 11 in a row from Sept. 13-24, 2003.