Michael Young's one-out RBI single in the 10th gave the Rangers a 4-3 victory over the Baltimore Orioles on Friday night after Gagne gave up a run in the ninth to snap his streak of 11 straight converted save opportunities this season.
"It's pretty incredible what he's been able to do," Young said of Gagne, who signed with Texas as a free agent after two injury-filled seasons. "We've gotten spoiled this season. But we found a way to pick him up the way he's done for us all year."
Travis Metcalf singled against Paul Shuey (0-1) leading off the 10th. Jerry Hairston sacrificed Metcalf to second and Ramon Vazquez walked before Young's line drive off the glove of diving third baseman Chris Gomez bounced into left field. Metcalf crossed the plate with the winning run well ahead of left fielder Jay Gibbons' throw.
Joaquin Benoit (3-2) pitched a perfect 10th to get the win.
Rangers starter Kameron Loe allowed five hits in six-plus shutout innings but Gagne, failed to close, snapping his overall streak at 30 in a row. His last blown save was on Aug. 18, 2004, against Florida as a member of the Los Angeles Dodgers.
Brad Wilkerson hit his fifth homer in the last seven games for Texas, which has won five of seven.
Nick Markakis was 3-for-4 for the Orioles.
Loe, looking for his career-high fifth straight victory, struck out three and walked three. He began the season in the bullpen and was sent to the minors in early June after an ineffective stretch as a starter.
C.J. Wilson relieved Loe, who threw 103 pitches, after Gomez led off the seventh with a double.
The Orioles went on to load the bases on two walks, then Wilson threw a wild pitch that bounced off the wall behind home plate and directly to catcher Adam Melhuse.
Melhuse made a diving tag on Gomez, who was called out by home plate umpire Brian Knight on a close play that brought interim manager Dave Trembley out of the dugout to argue.
After the game, Knight told a pool reporter that he was wrong on the play.
"I've seen the replay and I see that I missed the call," Knight said. "On that kind of play, I was fighting to get the best position I could get and called what I saw at the moment. I just saw the tag beating him."
Markakis followed with a two-run double to pull the Orioles within 3-2.
Baltimore starter Jeremy Guthrie gave up three runs and five hits in six innings, striking out three and walking three.
Guthrie, claimed on waivers from Cleveland in January, had gone at least seven innings in nine of his previous 10 starts.
Wilkerson's two-run homer in the sixth, his 14th, stretched Texas' lead to 3-0.
"I had thrown him a lot of sliders, even with two strikes," Guthrie said. "He'd seen it and he was guessing on it. The location wasn't terrible. The pitch wasn't super sharp, but he hit it a long way and did a good job keeping it fair."
The Rangers scored the game's first run on Vazquez's sacrifice fly in the third.
- Texas hasn't allowed a homer in six straight games for the first time since 1998.
- Guthrie was the third consecutive rookie starter for the Orioles. The last time Baltimore had rookies make three consecutive starts was Sept. 6-8, 2004, when Daniel Cabrera, Matt Riley and Erik Bedard took the mound in successive games in a series against Minnesota.
- Baltimore SS Freddie Bynum left the game in the third with a strained hamstring after his foot struck first base awkwardly while running out a grounder. Fahey took over for Bynum.
- The Orioles are 8-8 since Trembley took over from Sam Perlozzo on June 18.