Johan Santana (4-2), who had been scheduled to start for the Mets at Yankee Stadium, was pushed back to Saturday and will be followed Sunday night by Oliver Perez (3-3).
Yankees manager Joe Girardi, who said earlier Friday he would keep his pitchers in order, changed his mind and skipped Darrell Rasner. Andy Pettitte (3-4) will start Saturday against Santana, followed Sunday by Chien-Ming Wang (6-1).
The Mets already have a day-night doubleheader Tuesday at Atlanta and didn't want to schedule another doubleheader for this week.
The game likely will be made up in June. It could be rescheduled as part of a two-ballpark doubleheader during the June 27-29 series, when the Yankees are slated to make their final trip to Shea Stadium.
"It's a strong possibility. It seems to be directed that way," Yankees general manager Brian Cashman said.
The teams have played a game in each ballpark on the same day twice before: July 8, 2000, and June 28, 2003.