DENVER -- Miguel Montero predicted this kind of night for himself, an evening he would long remember.
He told Henry Blanco as they hung around the batting cage before the game that he was going to have "one of those crazy days when you get six or seven RBI. ... So, I guess I called it."
Montero drove in a career-high six runs, Paul Goldschmidt hit a go-ahead, three-run double in the eighth inning and the Arizona Diamondbacks sent the Colorado Rockies to their sixth consecutive loss 16-8 on Wednesday night.
The Rockies led 8-5 when the Diamondbacks scored six times in the eighth to reclaim the lead. They were hardly done, adding five more in the ninth to turn a close game into a runaway. The Diamondbacks tied a season high with 21 hits.
The top five hitters in the lineup had three hits each and combined for 14 RBI. Montero led the way as he drove in two runs on sacrifice flies, had a run-scoring single and hit a three-run homer in the ninth.
"It was awesome," Montero said.
Lyles used two hands to catch the ball when it was thrown back to him then left after the fourth.
"I knew something was wrong, because I've never felt that feeling before," said Lyles, who was wearing a bandage on his hand. "I didn't want to come out in the first, make the bullpen go nine. Thankfully, we got four innings."
Asked how long Lyles might be out, Rockies manager Walt Weiss said, "for a little bit."
Arizona surrendered four runs in the seventh to fall behind, but responded right away as Brothers imploded. The reliever gave up four straight singles, including a run-scoring liner by Chris Owings, and then then walked Gerardo Parra with the bases loaded to bring in another run. Nick Masset was summoned from the bullpen and promptly gave up Goldschmidt's double down the line.
"You're just looking for something you can hit hard," Goldschmidt explained. "The pitch ran a little bit inside but I think it was right on the corner and I was able to hit it."
Didi Gregorius led off the game with a solo homer as Arizona built an early 4-0 lead.
The Rockies came back with four runs in the fifth and four more in the seventh. D.J. LeMahieu's two-out infield single in the seventh tied the game and a throwing error by Owings at shortstop allowed the Rockies to take the lead. Pinch-hitter Drew Stubbs also added a two-run single.
Brothers faced five batters without getting an out. He allowed five runs.
"I'm not going to talk about Rex's situation right now, as far as his future," Weiss said. "Just got to keep working through it, like all of us do. It's up to us to turn this thing around, each guy. Nobody is going to do it for us."
Arizona starter Josh Collmenter, coming off a complete-game win, was cruising until the fifth when the Rockies broke out of their offensive funk. Troy Tulowitzki had a two-run double and Michael Cuddyer followed with a two-run single.
Tulowitzki slid just past Montero's tag for the tying run.
Diamondbacks manager Kirk Gibson challenged the play but after a quick review, the call was upheld.
Tulowitzki leads the majors in batting (.354) and All-Star votes (1,419,718).
"With the streak we've been on, to have Lyles break his hand, it's unfortunate," Tulowitzki said. "We've had a lot of hand injuries."
Before the game, Rockies All-Star outfielder Carlos Gonzalez was placed on the 15-day disabled list with an inflamed left index finger. It's another big bat out of the lineup as third baseman Nolan Arenado (fractured finger) went on the DL on May 24.
The Diamondbacks said on their Twitter account Wednesday that INF Cliff Pennington underwent surgery to fix a partially torn ligament in his left thumb. ... Arizona will send RHP Bronson Arroyo (4-4) to the mound in the series finale Thursday, while the Rockies counter with RHP Juan Nicasio (5-3). ... Prized prospect RHP Eddie Butler will make his major-league debut for Colorado on Friday.