TORONTO -- In a short matter of time, Edwin Encarnacion came up with a fitting rhyme.
Encarnacion launched a slider from Brandon Kintzler into the second deck for his 26th home run.
It was 4-all when Jose Reyes led off the ninth with a double against Will Smith (1-1). Melky Cabrera was intentionally walked and Kintzler came on to face Anthony Gose, who failed to advance the runners with a bunt as Reyes was forced at third.
Darin Mastroianni struck out, but Encarnacion ended it with his 26th home run.
Kintzler fell behind Encarnacion 3-1 before the drive.
"I should have just bounced a sinker and walked him or thrown the slider away off the plate," Kintzler said. "It definitely didn't go where I planned it."
Casey Janssen (3-0) worked one inning for the win.
The Brewers lost their third straight and were swept in the two-game series between division leaders, the first time this season they've been swept in a series of any length. Only the Los Angeles Dodgers have not been swept this season.
"We had good games with them, they're a good team," Kintzler said. "First place against first place."
With Bautista starting at designated hitter for the second straight game and Adam Lind at first base, Cabrera moved to right field and Encarnacion made his fourth career appearance in left. Bautista, who has been bothered by a strained left hamstring, hopes to return to the outfield Thursday.
Brewers outfielder Khris Davis was held out with a strained left shoulder. Davis, who left Tuesday's game in the seventh after he was injured sliding into second base, is expected to return Friday at Cincinnati. The Brewers are off Thursday.
Milwaukee opened the scoring with a two-out rally in the first on an RBI single by Carlos Gomez but Toronto answered in the bottom half when Bautista clubbed a two-out homer, his second in two days.
The Brewers reclaimed the lead with a three-run third. Ryan Braun hit a two-run triple and scored on Jonathan Lucroy's sacrifice fly.
Lind hit an RBI double in the bottom half and the Blue Jays tied it in the fourth on a two-run shot to right by Francisco, his first homer since June 20.
Milwaukee right-hander Wily Peralta allowed four runs and nine hits in six innings. He walked three and struck out four.
"Wily was all over the place again with his command but he did manage to give us innings and keep it tied," Brewers manager Ron Roenicke said. "We've got to get him locked in better and making some consistent pitches."
Blue Jays left-hander J.A. Happ allowed four runs and six hits in seven innings. He walked none and struck out four.
Roenicke and Blue Jays manager John Gibbons were both ejected for arguing on separate plays in the eighth.
Roenicke was ejected for the first time this season after arguing with first base umpire Phil Cuzzi that Toronto's Steve Tolleson had swung at a two-strike pitch that hit him in the right foot.
"Phil said he didn't swing on it," Roenicke said. "So I started to turn away and I looked at Phil and I just said 'You missed it,' and he kicked me out. That's a really bad job on Phil's part. If he can't take more than that, then he shouldn't be doing this."
One batter later, Tolleson was ruled safe as he advanced to second on a wild pitch. Bench coach Jerry Narron came out to argue and the call was overturned following review.
That brought Gibbons out for an argument with plate umpire and crew chief Greg Gibson, leading to the second ejection for Gibbons this season.
The Blue Jays signed first-round draft picks RHP Jeff Hoffman and C Max Pentecost. Hoffman was selected ninth overall while Pentecost was picked 11th. ... Milwaukee opens a three-game series at Cincinnati on Friday. Brewers RHP Kyle Lohse (9-2) faces Reds RHP Alfredo Simon (10-3). ... Toronto begins a four-game series at Oakland on Thursday. Blue Jays RHP R.A. Dickey faces Athletics RHP Sonny Gray (7-3).