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| All-Time Pitching Leaders | ||
| Career Earned Run Average Leaders | ||
| Rank | Player | ERA |
| 1. | Eddie Cicotte | 2.20 |
| 2. | Hippo Vaughn | 2.34 |
| 3. | Walter Johnson | 2.36 |
| 4. | Slim Sallee | 2.51 |
| 5. | Hoyt Wilhelm | 2.53 |
| 6. | Grover Alexander | 2.56 |
| 7. | Dick Rudolph | 2.62 |
| 8. | Claude Hendrix | 2.65 |
| 9. | Fred Toney | 2.70 |
| 10. | Whitey Ford | 2.75 |
| 11. | Sandy Koufax | 2.76 |
| 12. | Jeff Pfeffer | 2.78 |
| 13. | Lefty Tyler | 2.79 |
| Dutch Leonard | 2.79 | |
| 15. | Jim Palmer | 2.86 |
| Andy Messersmith | 2.86 | |
| Tom Seaver | 2.86 | |
| 18. | Stan Coveleski | 2.89 |
| Juan Marichal | 2.89 | |
| 20. | Wilbur Cooper | 2.90 |
| 21. | Babe Adams | 2.91 |
| Bob Gibson | 2.91 | |
| 23. | Carl Mays | 2.92 |
| Dean Chance | 2.92 | |
| 25. | Pedro Martinez | 2.93 |
| Active players shown in CAPS | Last Updated: Fri May 25 08:15:04 EDT 2012 | ||
