Pedroia took a shot to the face by Logan Forsythe while covering second base in the second inning. He was replaced by Will Middlebrooks. Pedroia is hitting .280 with seven homers and 51 RBI over 535 at-bats this season.
Worley picked up his first win since Aug. 8. He owns a 3.01 ERA and a 1.22 WHIP over 86 2/3 innings of work. He will make his next start Friday against the Cubs at Wrigley Field.
Simon has allowed three-plus runs in three of his last four starts. He owns a 3.28 ERA and a 1.17 WHIP over 27 starts (167 1/3 innings). His next start will come Friday at home against the Mets.
"It's getting better," Jackson said. "Just needed rest and recovery."
Jackson is hoping to return at some point during the final month of the season, though the Cubs surely won't rush him back. He had a 6.09 ERA in 139 innings of work prior to the injury.
"I'd be really shocked if he played," Girardi told MLB.com, after Saturday's loss. "I think it was wishful thinking on his part [to play Saturday]. He was trying to gut it out, but there was no way."
Ellsbury suffered the injury during Friday's game, and will not receive an official diagnosis until he can be checked by team doctors in New York.
Sanchez set the Yankees down in order over his two innings of work, striking out three of six batters faced on 28 total pitches. He has allowed just four runs over 21 2/3 innings since making his major-league debut, while striking out 20 batters and walking just three.
Petricka was not perfect Saturday, but he was good enough after a few subpar appearances. He retired the side on 18 pitches, while allowing one hit and one walk, and striking out one batter.
Petricka has 10 saves in 13 opportunities this season, while holding a 2.81 ERA and 1.36 WHIP in 64 innings of work.
The Cubs got to Masterson in the second inning for one run, but things came apart in the fourth inning. Masterson was tagged for a pair of solo home runs in the fourth, followed by one in the fifth before he was listed, after allowing five runs on six hits and a walk in 4 1/3 innings. He struck out five batters on 82 pitches in the loss.
The Cardinals acquired Masterson in July with the intention of making him a reclamation project, but that has not worked out so far. He has a 7.90 ERA in six starts since joining the Cardinals, and his rotation spot no longer appears assured. His next start is currently scheduled for Thursday in Milwaukee.