| Basic Stats | Extended Stats |
| Wins | ||||||||||||||||||
| Player | Pos | Team | GP | GS | IP | W | L | SV | SVO | H | R | HR | ER | ERA | BB | K | TP | WHIP |
| Sam Demel | RP | NYY | 5 | 0 | 2.1 | 1 | 0 | 0 | 0 | 10 | 11 | 4 | 11 | 42.43 | 3 | 1 | 46 | 5.57 |
| Ryan Verdugo | SP | KC | 2 | 0 | 1.2 | 1 | 0 | 0 | 0 | 4 | 3 | 0 | 3 | 16.20 | 2 | 1 | 46 | 3.60 |
| Ryan Robowski | RP | DET | 2 | 0 | 2.0 | 1 | 1 | 0 | 1 | 4 | 6 | 1 | 6 | 27.00 | 3 | 3 | 29 | 3.50 |
| John Lamb | SP | KC | 2 | 0 | 2.0 | 1 | 0 | 0 | 0 | 5 | 1 | 0 | 1 | 4.50 | 1 | 1 | 35 | 3.00 |
| Travis Blackley | SP | OAK | 7 | 2 | 12.2 | 1 | 1 | 1 | 3 | 27 | 20 | 3 | 20 | 14.21 | 6 | 12 | 121 | 2.61 |
| Frank Herrmann | RP | CLE | 2 | 0 | 2.0 | 1 | 0 | 0 | 0 | 5 | 4 | 1 | 4 | 18.00 | 0 | 0 | 13 | 2.50 |
| Jesse Crain | RP | CHW | 4 | 0 | 3.2 | 1 | 0 | 0 | 1 | 8 | 6 | 0 | 5 | 12.27 | 1 | 5 | 29 | 2.45 |
| Chris Dwyer | SP | KC | 1 | 1 | 1.2 | 1 | 0 | 0 | 0 | 1 | 3 | 0 | 2 | 10.80 | 3 | 1 | 40 | 2.40 |
| Jerome Williams | SP | LAA | 6 | 3 | 14.2 | 1 | 1 | 0 | 0 | 31 | 15 | 2 | 14 | 8.59 | 4 | 15 | 152 | 2.39 |
| Steven Wright | SP | BOS | 4 | 1 | 7.1 | 1 | 1 | 0 | 1 | 10 | 7 | 0 | 7 | 8.59 | 7 | 6 | 49 | 2.32 |
| Tim Collins | RP | KC | 9 | 0 | 8.2 | 2 | 0 | 0 | 2 | 15 | 11 | 4 | 11 | 11.42 | 5 | 11 | 195 | 2.31 |
| Joe Saunders | SP | SEA | 4 | 3 | 11.2 | 1 | 1 | 0 | 0 | 20 | 17 | 1 | 15 | 11.57 | 6 | 4 | 81 | 2.23 |
| Jeremy Jeffress | RP | TOR | 11 | 1 | 13.0 | 1 | 0 | 0 | 0 | 18 | 12 | 4 | 11 | 7.62 | 10 | 14 | 116 | 2.15 |
| Alex White | SP | HOU | 7 | 6 | 20.2 | 1 | 1 | 0 | 0 | 36 | 19 | 3 | 18 | 7.84 | 8 | 11 | 107 | 2.13 |
| Bruce Rondon | RP | DET | 13 | 0 | 12.1 | 2 | 1 | 0 | 1 | 17 | 8 | 2 | 8 | 5.84 | 9 | 19 | 124 | 2.11 |
| Brett Myers | SP | CLE | 6 | 6 | 21.0 | 2 | 3 | 0 | 0 | 36 | 23 | 3 | 21 | 9.00 | 8 | 14 | 81 | 2.10 |
| Ricky Romero | SP | TOR | 5 | 5 | 13.0 | 1 | 1 | 0 | 0 | 17 | 11 | 3 | 9 | 6.23 | 10 | 8 | 83 | 2.08 |
| Ryan Cook | RP | OAK | 9 | 0 | 7.1 | 1 | 1 | 0 | 2 | 10 | 5 | 2 | 5 | 6.14 | 5 | 4 | 75 | 2.05 |
| Daniel McCutchen | SP | BAL | 7 | 0 | 7.1 | 1 | 0 | 2 | 3 | 13 | 5 | 1 | 5 | 6.14 | 2 | 4 | 48 | 2.05 |
| Neil Ramirez | SP | TEX | 3 | 1 | 3.0 | 1 | 0 | 0 | 0 | 6 | 5 | 2 | 5 | 15.00 | 0 | 2 | 32 | 2.00 |
| C.J. Wilson | SP | LAA | 4 | 4 | 12.2 | 2 | 0 | 0 | 0 | 23 | 12 | 3 | 10 | 7.11 | 2 | 11 | 113 | 1.97 |
| Wei-Yin Chen | SP | BAL | 3 | 3 | 7.2 | 1 | 1 | 0 | 0 | 11 | 9 | 3 | 7 | 8.22 | 4 | 6 | 34 | 1.96 |
| David Martinez | RP | HOU | 3 | 1 | 6.2 | 1 | 0 | 0 | 1 | 12 | 4 | 0 | 4 | 5.40 | 1 | 4 | 62 | 1.95 |
| A.J. Schugel | RP | LAA | 3 | 2 | 7.0 | 1 | 0 | 0 | 0 | 12 | 4 | 1 | 4 | 5.14 | 1 | 4 | 49 | 1.86 |
| Mike Pelfrey | SP | MIN | 6 | 6 | 18.1 | 1 | 2 | 0 | 0 | 28 | 13 | 1 | 13 | 6.38 | 6 | 15 | 108 | 1.85 |
| Chris Tillman | SP | BAL | 2 | 2 | 4.1 | 1 | 0 | 0 | 0 | 5 | 2 | 1 | 2 | 4.15 | 3 | 4 | 45 | 1.85 |
| Kevin Jepsen | RP | LAA | 6 | 0 | 6.0 | 1 | 0 | 0 | 1 | 9 | 3 | 0 | 3 | 4.50 | 2 | 3 | 46 | 1.83 |
| Ryan Rowland-Smith | SP | BOS | 2 | 0 | 1.2 | 1 | 0 | 0 | 0 | 3 | 2 | 0 | 2 | 10.80 | 0 | 2 | 8 | 1.80 |
| John Ely | SP | HOU | 5 | 1 | 10.0 | 1 | 1 | 0 | 1 | 14 | 14 | 4 | 11 | 9.90 | 4 | 10 | 78 | 1.80 |
| Ramon Troncoso | RP | CHW | 13 | 0 | 12.1 | 1 | 0 | 1 | 3 | 19 | 6 | 0 | 5 | 3.65 | 3 | 7 | 71 | 1.78 |
| Jeremy Bonderman | SP | SEA | 5 | 3 | 15.1 | 2 | 1 | 0 | 0 | 24 | 15 | 2 | 15 | 8.80 | 3 | 7 | 178 | 1.76 |
| Dan Straily | SP | OAK | 7 | 6 | 21.2 | 2 | 2 | 0 | 0 | 31 | 17 | 2 | 14 | 5.82 | 7 | 20 | 248 | 1.75 |
| Doug Fister | SP | DET | 7 | 6 | 25.1 | 2 | 3 | 0 | 0 | 32 | 21 | 6 | 16 | 5.68 | 12 | 22 | 231 | 1.74 |
| Collin Balester | SP | TEX | 7 | 0 | 7.0 | 1 | 0 | 0 | 1 | 9 | 7 | 2 | 7 | 9.00 | 3 | 7 | 81 | 1.71 |
| Luke Hochevar | SP | KC | 9 | 2 | 14.0 | 1 | 0 | 0 | 1 | 17 | 11 | 2 | 11 | 7.07 | 7 | 15 | 178 | 1.71 |
| Gavin Floyd | SP | CHW | 5 | 5 | 21.2 | 1 | 2 | 0 | 0 | 33 | 16 | 5 | 15 | 6.23 | 4 | 23 | 152 | 1.71 |
| Hideki Okajima | RP | OAK | 9 | 0 | 9.1 | 1 | 0 | 1 | 2 | 12 | 6 | 3 | 6 | 5.79 | 4 | 6 | 72 | 1.71 |
| Taijuan Walker | SP | SEA | 4 | 0 | 7.0 | 1 | 0 | 0 | 1 | 7 | 4 | 1 | 4 | 5.14 | 5 | 4 | 104 | 1.71 |
| Randy Wells | SP | TEX | 5 | 4 | 14.0 | 1 | 0 | 0 | 0 | 18 | 8 | 4 | 7 | 4.50 | 6 | 10 | 158 | 1.71 |
| Jeremy Hellickson | SP | TB | 6 | 4 | 22.2 | 2 | 1 | 0 | 0 | 33 | 19 | 5 | 17 | 6.75 | 5 | 13 | 125 | 1.68 |
| Marquis Fleming | RP | TB | 2 | 0 | 3.0 | 1 | 0 | 0 | 1 | 2 | 2 | 1 | 2 | 6.00 | 3 | 3 | 31 | 1.67 |
| Xavier Cedeno | RP | HOU | 7 | 0 | 6.0 | 1 | 0 | 1 | 1 | 8 | 6 | 1 | 4 | 6.00 | 2 | 4 | 45 | 1.67 |
| Mark Buehrle | SP | TOR | 6 | 6 | 18.0 | 1 | 0 | 0 | 0 | 23 | 9 | 3 | 9 | 4.50 | 7 | 12 | 145 | 1.67 |
| Adam Russell | RP | BAL | 10 | 0 | 9.2 | 2 | 1 | 1 | 5 | 11 | 6 | 0 | 6 | 5.59 | 5 | 9 | 66 | 1.66 |
| Derek Lowe | SP | TEX | 4 | 3 | 10.1 | 1 | 0 | 0 | 0 | 13 | 6 | 4 | 6 | 5.23 | 4 | 5 | 130 | 1.65 |
| Sugar Ray Marimon | SP | KC | 4 | 1 | 7.1 | 1 | 0 | 0 | 0 | 10 | 5 | 0 | 5 | 6.14 | 2 | 2 | 112 | 1.64 |
| Tom Wilhelmsen | RP | SEA | 10 | 0 | 11.0 | 1 | 1 | 0 | 1 | 14 | 6 | 0 | 6 | 4.91 | 4 | 13 | 128 | 1.64 |
| Jason Vargas | SP | LAA | 6 | 6 | 22.2 | 1 | 2 | 0 | 0 | 30 | 19 | 4 | 19 | 7.54 | 7 | 18 | 133 | 1.63 |
| Ernesto Frieri | RP | LAA | 11 | 0 | 10.0 | 2 | 2 | 1 | 1 | 12 | 7 | 0 | 7 | 6.30 | 4 | 5 | 51 | 1.60 |
| Bartolo Colon | SP | OAK | 6 | 3 | 20.0 | 1 | 2 | 1 | 2 | 31 | 17 | 2 | 14 | 6.30 | 1 | 22 | 193 | 1.60 |
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