| Basic Stats | Extended Stats |
| Wins | ||||||||||||||||||
| Player | Pos | Team | GP | GS | IP | W | L | SV | SVO | H | R | HR | ER | ERA | BB | K | TP | WHIP |
| Jim Johnson | RP | BAL | 21 | 0 | 20.1 | 1 | 4 | 14 | 16 | 20 | 10 | 2 | 9 | 3.98 | 6 | 17 | 325 | 1.28 |
| Addison Reed | RP | CHW | 19 | 0 | 19.0 | 1 | 0 | 14 | 15 | 13 | 5 | 0 | 5 | 2.37 | 8 | 22 | 307 | 1.11 |
| Joe Nathan | RP | TEX | 17 | 0 | 16.0 | 1 | 0 | 12 | 12 | 12 | 4 | 1 | 4 | 2.25 | 6 | 15 | 262 | 1.12 |
| Fernando Rodney | RP | TB | 16 | 0 | 15.1 | 1 | 2 | 7 | 10 | 12 | 9 | 2 | 9 | 5.28 | 15 | 23 | 328 | 1.76 |
| Greg Holland | RP | KC | 15 | 0 | 14.0 | 1 | 1 | 7 | 9 | 13 | 7 | 0 | 5 | 3.21 | 7 | 21 | 257 | 1.43 |
| Glen Perkins | RP | MIN | 15 | 0 | 14.2 | 1 | 0 | 8 | 8 | 9 | 5 | 1 | 5 | 3.07 | 5 | 23 | 251 | 0.95 |
| Chris Perez | RP | CLE | 15 | 0 | 15.0 | 2 | 0 | 6 | 8 | 12 | 4 | 3 | 3 | 1.80 | 5 | 16 | 260 | 1.13 |
| Andrew Bailey | RP | BOS | 13 | 0 | 12.1 | 1 | 0 | 5 | 6 | 6 | 2 | 1 | 2 | 1.46 | 4 | 20 | 208 | 0.81 |
| Jake McGee | RP | TB | 19 | 0 | 15.1 | 1 | 2 | 0 | 3 | 19 | 15 | 4 | 15 | 8.80 | 10 | 20 | 334 | 1.89 |
| Kelvin Herrera | RP | KC | 17 | 0 | 18.1 | 2 | 3 | 2 | 3 | 17 | 9 | 7 | 9 | 4.42 | 7 | 23 | 319 | 1.31 |
| Darren O'Day | RP | BAL | 20 | 0 | 19.2 | 2 | 0 | 1 | 3 | 15 | 5 | 1 | 4 | 1.83 | 9 | 20 | 343 | 1.22 |
| Hector Ambriz | RP | HOU | 20 | 0 | 19.0 | 1 | 2 | 0 | 2 | 24 | 17 | 3 | 13 | 6.16 | 8 | 16 | 344 | 1.68 |
| Casey Fien | RP | MIN | 21 | 0 | 18.1 | 1 | 2 | 0 | 2 | 15 | 9 | 3 | 9 | 4.42 | 5 | 16 | 301 | 1.09 |
| Junichi Tazawa | RP | BOS | 19 | 0 | 18.1 | 3 | 2 | 0 | 2 | 17 | 6 | 3 | 6 | 2.95 | 3 | 23 | 292 | 1.09 |
| Aaron Loup | RP | TOR | 17 | 0 | 22.0 | 1 | 3 | 1 | 2 | 22 | 11 | 2 | 7 | 2.86 | 5 | 13 | 349 | 1.23 |
| Brian Matusz | RP | BAL | 20 | 0 | 16.2 | 1 | 0 | 0 | 2 | 7 | 5 | 2 | 5 | 2.70 | 3 | 17 | 241 | 0.60 |
| Cody Allen | RP | CLE | 17 | 0 | 19.1 | 1 | 0 | 1 | 2 | 15 | 6 | 2 | 5 | 2.33 | 6 | 24 | 318 | 1.09 |
| Jerry Blevins | RP | OAK | 19 | 0 | 19.2 | 2 | 0 | 0 | 2 | 13 | 5 | 2 | 5 | 2.29 | 1 | 20 | 299 | 0.71 |
| Steve Delabar | RP | TOR | 19 | 0 | 23.0 | 3 | 1 | 0 | 2 | 16 | 6 | 1 | 5 | 1.96 | 14 | 28 | 403 | 1.30 |
| Drew Smyly | RP | DET | 15 | 0 | 28.0 | 2 | 0 | 1 | 2 | 20 | 6 | 0 | 6 | 1.93 | 7 | 29 | 471 | 0.96 |
| Kyle Farnsworth | RP | TB | 14 | 0 | 9.2 | 2 | 0 | 0 | 1 | 18 | 9 | 3 | 9 | 8.38 | 3 | 5 | 149 | 2.17 |
| Esmil Rogers | RP | TOR | 20 | 0 | 19.2 | 1 | 2 | 0 | 1 | 25 | 13 | 2 | 13 | 5.95 | 7 | 11 | 344 | 1.63 |
| Garrett Richards | RP | LAA | 15 | 4 | 38.1 | 2 | 3 | 0 | 1 | 39 | 24 | 4 | 24 | 5.63 | 12 | 26 | 633 | 1.33 |
| Matt Lindstrom | RP | CHW | 21 | 0 | 17.0 | 2 | 2 | 0 | 1 | 14 | 9 | 0 | 9 | 4.76 | 10 | 15 | 266 | 1.41 |
| Dane De La Rosa | RP | LAA | 20 | 0 | 21.2 | 1 | 1 | 0 | 1 | 20 | 11 | 1 | 11 | 4.57 | 7 | 20 | 347 | 1.25 |
| Paul Clemens | RP | HOU | 12 | 0 | 27.0 | 1 | 1 | 0 | 1 | 21 | 13 | 7 | 12 | 4.00 | 7 | 19 | 412 | 1.04 |
| Josh Roenicke | RP | MIN | 15 | 0 | 20.2 | 1 | 1 | 0 | 1 | 18 | 9 | 4 | 9 | 3.92 | 11 | 15 | 325 | 1.40 |
| Tim Collins | RP | KC | 13 | 0 | 14.0 | 1 | 1 | 0 | 1 | 12 | 7 | 0 | 6 | 3.86 | 4 | 15 | 238 | 1.14 |
| David Phelps | RP | NYY | 10 | 4 | 42.1 | 2 | 2 | 0 | 1 | 38 | 19 | 4 | 18 | 3.83 | 18 | 46 | 722 | 1.32 |
| Troy Patton | RP | BAL | 17 | 0 | 19.0 | 1 | 0 | 0 | 1 | 20 | 10 | 2 | 8 | 3.79 | 10 | 8 | 319 | 1.58 |
| Darren Oliver | RP | TOR | 17 | 0 | 17.0 | 2 | 1 | 0 | 1 | 19 | 9 | 2 | 6 | 3.18 | 6 | 11 | 258 | 1.47 |
| David Robertson | RP | NYY | 18 | 0 | 17.1 | 2 | 0 | 0 | 1 | 11 | 6 | 3 | 6 | 3.12 | 4 | 21 | 253 | 0.87 |
| Ryan Cook | RP | OAK | 19 | 0 | 19.2 | 1 | 0 | 0 | 1 | 14 | 5 | 0 | 4 | 1.83 | 7 | 25 | 334 | 1.07 |
| Tommy Hunter | RP | BAL | 15 | 0 | 23.1 | 3 | 1 | 1 | 1 | 15 | 5 | 4 | 4 | 1.54 | 4 | 18 | 358 | 0.81 |
| Adam Warren | RP | NYY | 8 | 0 | 19.2 | 1 | 0 | 1 | 1 | 15 | 3 | 1 | 3 | 1.37 | 6 | 15 | 321 | 1.07 |
| Sean Doolittle | RP | OAK | 20 | 0 | 19.0 | 3 | 0 | 0 | 1 | 8 | 2 | 2 | 2 | 0.95 | 3 | 19 | 266 | 0.58 |
| Joe Smith | RP | CLE | 15 | 0 | 13.2 | 1 | 0 | 1 | 1 | 8 | 1 | 0 | 1 | 0.66 | 3 | 14 | 200 | 0.80 |
| Mark Lowe | RP | LAA | 10 | 0 | 10.2 | 1 | 0 | 0 | 0 | 11 | 12 | 1 | 12 | 10.13 | 10 | 7 | 234 | 1.97 |
| Donnie Veal | RP | CHW | 13 | 0 | 6.2 | 1 | 0 | 0 | 0 | 10 | 8 | 1 | 7 | 9.45 | 8 | 5 | 145 | 2.70 |
| Brad Peacock | SP | HOU | 6 | 5 | 22.0 | 1 | 3 | 0 | 0 | 29 | 23 | 7 | 23 | 9.41 | 13 | 19 | 469 | 1.91 |
| Michael Roth | RP | LAA | 9 | 1 | 14.0 | 1 | 1 | 0 | 0 | 21 | 14 | 0 | 14 | 9.00 | 3 | 14 | 251 | 1.71 |
| Alfredo Aceves | SP | BOS | 5 | 3 | 17.2 | 1 | 1 | 0 | 0 | 25 | 18 | 6 | 17 | 8.66 | 12 | 14 | 334 | 2.09 |
| Derek Lowe | RP | TEX | 8 | 0 | 12.1 | 1 | 0 | 0 | 0 | 14 | 11 | 3 | 11 | 8.03 | 3 | 8 | 185 | 1.38 |
| Aaron Harang | SP | SEA | 5 | 5 | 24.2 | 1 | 4 | 0 | 0 | 30 | 20 | 6 | 20 | 7.30 | 5 | 23 | 451 | 1.42 |
| Dan Straily | SP | OAK | 5 | 5 | 26.0 | 1 | 2 | 0 | 0 | 26 | 22 | 3 | 21 | 7.27 | 12 | 27 | 457 | 1.46 |
| Jake Arrieta | SP | BAL | 4 | 4 | 19.0 | 1 | 1 | 0 | 0 | 15 | 14 | 1 | 14 | 6.63 | 16 | 20 | 365 | 1.63 |
| Jordan Lyles | SP | HOU | 4 | 4 | 19.0 | 1 | 1 | 0 | 0 | 25 | 15 | 3 | 14 | 6.63 | 8 | 17 | 347 | 1.74 |
| Mike Pelfrey | SP | MIN | 8 | 8 | 38.1 | 3 | 4 | 0 | 0 | 57 | 30 | 4 | 28 | 6.57 | 11 | 18 | 725 | 1.77 |
| Ivan Nova | SP | NYY | 4 | 4 | 16.2 | 1 | 1 | 0 | 0 | 23 | 12 | 1 | 12 | 6.48 | 8 | 18 | 345 | 1.86 |
| Mark Buehrle | SP | TOR | 9 | 9 | 54.0 | 1 | 3 | 0 | 0 | 64 | 40 | 11 | 38 | 6.33 | 16 | 34 | 911 | 1.48 |
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