| Basic Stats | Extended Stats |
| Strikeouts | ||||||||||||||||||
| Player | Pos | Team | GP | GS | IP | W | L | SV | SVO | H | R | HR | ER | ERA | BB | K | TP | WHIP |
| Alexi Ogando | RP | TEX | 7 | 5 | 25.1 | 2 | 1 | 0 | 0 | 19 | 13 | 5 | 10 | 3.55 | 15 | 22 | 298 | 1.34 |
| Ervin Santana | SP | KC | 6 | 6 | 23.0 | 1 | 1 | 0 | 0 | 30 | 14 | 2 | 12 | 4.70 | 4 | 21 | 267 | 1.48 |
| Aaron Harang | SP | LAD | 5 | 5 | 18.2 | 1 | 2 | 0 | 0 | 28 | 20 | 3 | 17 | 8.20 | 9 | 13 | 264 | 1.98 |
| Patrick Corbin | SP | ARI | 7 | 5 | 25.2 | 3 | 0 | 0 | 0 | 25 | 8 | 1 | 8 | 2.81 | 9 | 26 | 261 | 1.32 |
| Blake Beavan | SP | SEA | 5 | 4 | 19.1 | 1 | 1 | 0 | 0 | 29 | 15 | 5 | 14 | 6.52 | 0 | 12 | 258 | 1.50 |
| Jason Marquis | SP | SD | 6 | 6 | 21.2 | 1 | 1 | 0 | 0 | 21 | 11 | 1 | 9 | 3.74 | 15 | 15 | 253 | 1.66 |
| Dan Straily | SP | OAK | 7 | 6 | 21.2 | 2 | 2 | 0 | 0 | 31 | 17 | 2 | 14 | 5.82 | 7 | 20 | 248 | 1.75 |
| Edwin Jackson | SP | CHC | 6 | 6 | 24.0 | 1 | 2 | 0 | 0 | 23 | 14 | 1 | 14 | 5.25 | 6 | 17 | 241 | 1.21 |
| Randall Delgado | SP | ARI | 6 | 4 | 19.1 | 2 | 1 | 0 | 0 | 30 | 17 | 3 | 16 | 7.45 | 8 | 10 | 238 | 1.97 |
| Jeremy Guthrie | SP | KC | 5 | 5 | 22.0 | 2 | 1 | 0 | 0 | 29 | 11 | 2 | 10 | 4.09 | 3 | 15 | 238 | 1.45 |
| Bronson Arroyo | SP | CIN | 5 | 5 | 23.0 | 1 | 2 | 0 | 0 | 30 | 9 | 3 | 8 | 3.13 | 2 | 6 | 237 | 1.39 |
| Doug Fister | SP | DET | 7 | 6 | 25.1 | 2 | 3 | 0 | 0 | 32 | 21 | 6 | 16 | 5.68 | 12 | 22 | 231 | 1.74 |
| Tyler Chatwood | RP | COL | 6 | 3 | 19.0 | 1 | 1 | 0 | 0 | 23 | 13 | 1 | 13 | 6.16 | 13 | 13 | 224 | 1.89 |
| Tyson Ross | SP | SD | 7 | 4 | 22.1 | 3 | 2 | 0 | 0 | 17 | 6 | 2 | 6 | 2.42 | 11 | 20 | 224 | 1.25 |
| Ubaldo Jimenez | SP | CLE | 7 | 6 | 30.0 | 2 | 2 | 0 | 0 | 33 | 16 | 3 | 16 | 4.80 | 7 | 22 | 224 | 1.33 |
| Juan Nicasio | SP | COL | 6 | 5 | 20.1 | 1 | 1 | 0 | 0 | 25 | 14 | 3 | 11 | 4.87 | 9 | 17 | 223 | 1.67 |
| Nick Tepesch | SP | TEX | 5 | 3 | 18.0 | 0 | 1 | 1 | 1 | 24 | 13 | 1 | 13 | 6.50 | 6 | 13 | 219 | 1.67 |
| David Phelps | RP | NYY | 7 | 7 | 28.0 | 3 | 3 | 0 | 0 | 27 | 13 | 2 | 13 | 4.18 | 9 | 27 | 217 | 1.29 |
| Derek Holland | SP | TEX | 4 | 4 | 17.0 | 2 | 1 | 0 | 0 | 19 | 4 | 1 | 4 | 2.12 | 1 | 16 | 216 | 1.18 |
| Ryan Vogelsong | SP | SF | 6 | 6 | 25.0 | 1 | 2 | 0 | 0 | 22 | 10 | 2 | 10 | 3.60 | 6 | 19 | 203 | 1.12 |
| Mike Minor | SP | ATL | 6 | 6 | 23.0 | 2 | 1 | 0 | 0 | 29 | 16 | 4 | 16 | 6.26 | 14 | 18 | 202 | 1.87 |
| Eric Stults | SP | SD | 6 | 6 | 23.0 | 2 | 2 | 0 | 0 | 25 | 17 | 3 | 15 | 5.87 | 6 | 9 | 201 | 1.35 |
| Freddy Garcia | SP | SD | 6 | 6 | 20.2 | 1 | 4 | 0 | 0 | 26 | 25 | 8 | 20 | 8.71 | 7 | 18 | 200 | 1.60 |
| Tommy Milone | SP | OAK | 6 | 6 | 23.1 | 3 | 0 | 0 | 0 | 28 | 12 | 3 | 12 | 4.63 | 5 | 17 | 199 | 1.41 |
| Mike Fiers | SP | MIL | 6 | 5 | 19.1 | 2 | 1 | 0 | 0 | 29 | 17 | 4 | 15 | 6.98 | 8 | 16 | 198 | 1.91 |
| Julio Teheran | SP | ATL | 6 | 6 | 26.0 | 3 | 1 | 0 | 0 | 7 | 3 | 2 | 3 | 1.04 | 9 | 35 | 196 | 0.62 |
| Tim Collins | RP | KC | 9 | 0 | 8.2 | 2 | 0 | 0 | 2 | 15 | 11 | 4 | 11 | 11.42 | 5 | 11 | 195 | 2.31 |
| Jeremy Hefner | RP | NYM | 8 | 5 | 25.1 | 1 | 0 | 0 | 0 | 26 | 13 | 8 | 13 | 4.62 | 7 | 21 | 193 | 1.30 |
| Luis Mendoza | SP | KC | 4 | 3 | 16.2 | 2 | 1 | 0 | 0 | 20 | 7 | 1 | 5 | 2.70 | 3 | 11 | 193 | 1.38 |
| Bartolo Colon | SP | OAK | 6 | 3 | 20.0 | 1 | 2 | 1 | 2 | 31 | 17 | 2 | 14 | 6.30 | 1 | 22 | 193 | 1.60 |
| Robbie Ross | RP | TEX | 9 | 3 | 19.1 | 3 | 0 | 0 | 0 | 20 | 5 | 2 | 5 | 2.33 | 8 | 14 | 191 | 1.45 |
| Justin Masterson | SP | CLE | 6 | 6 | 22.2 | 2 | 1 | 0 | 0 | 23 | 16 | 4 | 12 | 4.76 | 6 | 26 | 191 | 1.28 |
| Josh Johnson | SP | TOR | 6 | 4 | 20.0 | 5 | 0 | 0 | 0 | 12 | 6 | 3 | 6 | 2.70 | 3 | 23 | 185 | 0.75 |
| Tim Lincecum | SP | SF | 5 | 5 | 15.1 | 0 | 3 | 0 | 0 | 22 | 18 | 2 | 18 | 10.57 | 8 | 16 | 183 | 1.96 |
| Madison Bumgarner | SP | SF | 6 | 6 | 19.2 | 2 | 0 | 0 | 0 | 18 | 5 | 1 | 5 | 2.29 | 7 | 18 | 183 | 1.27 |
| Tim Hudson | SP | ATL | 7 | 7 | 30.0 | 2 | 1 | 0 | 0 | 32 | 13 | 3 | 13 | 3.90 | 7 | 11 | 180 | 1.30 |
| Travis Wood | SP | CHC | 6 | 3 | 20.1 | 3 | 1 | 0 | 0 | 19 | 10 | 1 | 10 | 4.43 | 11 | 19 | 179 | 1.48 |
| Luke Hochevar | SP | KC | 9 | 2 | 14.0 | 1 | 0 | 0 | 1 | 17 | 11 | 2 | 11 | 7.07 | 7 | 15 | 178 | 1.71 |
| Jeremy Bonderman | SP | SEA | 5 | 3 | 15.1 | 2 | 1 | 0 | 0 | 24 | 15 | 2 | 15 | 8.80 | 3 | 7 | 178 | 1.76 |
| Brad Peacock | SP | HOU | 8 | 4 | 22.2 | 0 | 1 | 1 | 1 | 18 | 8 | 0 | 7 | 2.78 | 7 | 17 | 175 | 1.10 |
| Chris Sale | SP | CHW | 5 | 5 | 23.1 | 4 | 0 | 0 | 0 | 17 | 10 | 5 | 10 | 3.86 | 4 | 16 | 175 | 0.90 |
| Adam Wainwright | SP | STL | 6 | 6 | 27.0 | 4 | 1 | 0 | 0 | 28 | 10 | 2 | 9 | 3.00 | 6 | 18 | 172 | 1.26 |
| John Lannan | SP | PHI | 6 | 5 | 21.0 | 1 | 2 | 0 | 0 | 29 | 18 | 3 | 18 | 7.71 | 5 | 15 | 172 | 1.62 |
| Dillon Gee | SP | NYM | 6 | 6 | 23.0 | 1 | 2 | 0 | 0 | 22 | 15 | 3 | 15 | 5.87 | 9 | 18 | 171 | 1.35 |
| Jarrod Parker | SP | OAK | 5 | 5 | 19.1 | 0 | 2 | 0 | 0 | 25 | 18 | 5 | 16 | 7.45 | 5 | 13 | 171 | 1.55 |
| Trevor Cahill | SP | ARI | 5 | 5 | 19.1 | 2 | 1 | 0 | 0 | 16 | 5 | 0 | 4 | 1.86 | 5 | 25 | 167 | 1.09 |
| Justin Verlander | SP | DET | 6 | 6 | 24.2 | 1 | 3 | 0 | 0 | 19 | 12 | 5 | 11 | 4.01 | 4 | 21 | 167 | 0.93 |
| Clayton Richard | SP | SD | 4 | 4 | 18.2 | 1 | 1 | 0 | 0 | 21 | 13 | 3 | 11 | 5.30 | 4 | 11 | 166 | 1.34 |
| Philip Humber | SP | HOU | 6 | 4 | 26.0 | 2 | 2 | 1 | 2 | 14 | 9 | 5 | 5 | 1.73 | 6 | 16 | 162 | 0.77 |
| Chad Gaudin | RP | SF | 11 | 2 | 17.2 | 2 | 0 | 0 | 0 | 20 | 5 | 0 | 5 | 2.55 | 3 | 15 | 161 | 1.30 |
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