| Basic Stats | Extended Stats |
| Saves | ||||||||||||||||||
| Player | Pos | Team | GP | GS | IP | W | L | SV | SVO | H | R | HR | ER | ERA | BB | K | TP | WHIP |
| Nick Tepesch | SP | TEX | 5 | 3 | 18.0 | 0 | 1 | 1 | 1 | 24 | 13 | 1 | 13 | 6.50 | 6 | 13 | 219 | 1.67 |
| Bartolo Colon | SP | OAK | 6 | 3 | 20.0 | 1 | 2 | 1 | 2 | 31 | 17 | 2 | 14 | 6.30 | 1 | 22 | 193 | 1.60 |
| Brad Peacock | SP | HOU | 8 | 4 | 22.2 | 0 | 1 | 1 | 1 | 18 | 8 | 0 | 7 | 2.78 | 7 | 17 | 175 | 1.10 |
| Philip Humber | SP | HOU | 6 | 4 | 26.0 | 2 | 2 | 1 | 2 | 14 | 9 | 5 | 5 | 1.73 | 6 | 16 | 162 | 0.77 |
| Tim Stauffer | SP | SD | 6 | 0 | 11.1 | 0 | 3 | 1 | 3 | 15 | 11 | 1 | 11 | 8.74 | 2 | 11 | 155 | 1.50 |
| Justin Grimm | SP | TEX | 4 | 1 | 9.1 | 0 | 2 | 1 | 1 | 15 | 10 | 2 | 10 | 9.64 | 6 | 9 | 133 | 2.25 |
| Travis Blackley | SP | OAK | 7 | 2 | 12.2 | 1 | 1 | 1 | 3 | 27 | 20 | 3 | 20 | 14.21 | 6 | 12 | 121 | 2.61 |
| Evan Meek | RP | TEX | 8 | 0 | 8.2 | 0 | 0 | 1 | 2 | 13 | 10 | 0 | 9 | 9.35 | 3 | 10 | 120 | 1.85 |
| Esmil Rogers | RP | TOR | 11 | 0 | 12.2 | 1 | 1 | 1 | 1 | 15 | 9 | 4 | 9 | 6.39 | 5 | 17 | 117 | 1.58 |
| Jeremy Horst | RP | PHI | 12 | 0 | 17.0 | 2 | 1 | 1 | 1 | 17 | 9 | 4 | 8 | 4.24 | 4 | 13 | 116 | 1.24 |
| Sean O'Sullivan | SP | SD | 7 | 3 | 13.1 | 1 | 0 | 1 | 2 | 7 | 3 | 0 | 2 | 1.35 | 6 | 7 | 114 | 0.98 |
| Jeurys Familia | SP | NYM | 12 | 0 | 13.1 | 2 | 0 | 1 | 1 | 11 | 4 | 1 | 3 | 2.03 | 8 | 13 | 111 | 1.43 |
| Dylan Axelrod | SP | CHW | 6 | 2 | 19.2 | 2 | 2 | 1 | 1 | 20 | 8 | 2 | 8 | 3.66 | 3 | 15 | 111 | 1.17 |
| Dan Wheeler | RP | KC | 12 | 0 | 12.0 | 0 | 0 | 3 | 7 | 14 | 2 | 1 | 2 | 1.50 | 1 | 14 | 110 | 1.25 |
| Johan Yan | RP | TEX | 10 | 0 | 9.1 | 0 | 1 | 2 | 3 | 5 | 4 | 2 | 3 | 2.89 | 3 | 9 | 110 | 0.86 |
| Trevor Bauer | SP | CLE | 5 | 1 | 14.0 | 1 | 0 | 1 | 1 | 14 | 9 | 1 | 7 | 4.50 | 4 | 9 | 109 | 1.29 |
| Evan Scribner | RP | OAK | 10 | 0 | 11.0 | 0 | 0 | 1 | 3 | 17 | 8 | 0 | 8 | 6.55 | 2 | 12 | 108 | 1.73 |
| Hector Rondon | SP | CHC | 11 | 0 | 10.0 | 2 | 0 | 1 | 1 | 9 | 2 | 1 | 2 | 1.80 | 2 | 9 | 107 | 1.10 |
| Joe Nathan | RP | TEX | 7 | 0 | 7.0 | 0 | 0 | 1 | 2 | 8 | 6 | 2 | 6 | 7.71 | 3 | 9 | 106 | 1.57 |
| Jair Jurrjens | SP | BAL | 6 | 3 | 14.2 | 1 | 1 | 1 | 1 | 15 | 10 | 1 | 8 | 4.91 | 7 | 6 | 103 | 1.50 |
| Alfredo Figaro | SP | MIL | 11 | 0 | 15.0 | 0 | 1 | 1 | 3 | 10 | 4 | 0 | 4 | 2.40 | 6 | 11 | 102 | 1.07 |
| Troy Patton | RP | BAL | 10 | 0 | 12.2 | 0 | 0 | 1 | 2 | 16 | 9 | 1 | 8 | 5.68 | 4 | 14 | 101 | 1.58 |
| T.J. McFarland | SP | BAL | 8 | 1 | 15.1 | 0 | 0 | 1 | 1 | 17 | 8 | 1 | 8 | 4.70 | 4 | 10 | 101 | 1.37 |
| Michael Olmsted | RP | MIL | 12 | 0 | 11.1 | 0 | 1 | 3 | 3 | 11 | 6 | 4 | 6 | 4.76 | 6 | 15 | 99 | 1.50 |
| Danny Farquhar | RP | SEA | 9 | 0 | 8.1 | 1 | 0 | 2 | 3 | 9 | 9 | 1 | 9 | 9.72 | 3 | 10 | 98 | 1.44 |
| Brian Omogrosso | RP | CHW | 10 | 0 | 12.1 | 0 | 1 | 1 | 2 | 7 | 2 | 0 | 0 | 0.00 | 6 | 5 | 95 | 1.05 |
| Luke Putkonen | RP | DET | 10 | 0 | 13.2 | 0 | 0 | 2 | 3 | 14 | 7 | 0 | 6 | 3.95 | 5 | 14 | 94 | 1.39 |
| Dale Thayer | RP | SD | 10 | 0 | 9.2 | 0 | 0 | 1 | 1 | 10 | 8 | 3 | 5 | 4.66 | 2 | 9 | 94 | 1.24 |
| Nate Adcock | RP | KC | 8 | 0 | 8.1 | 2 | 0 | 1 | 2 | 2 | 1 | 0 | 1 | 1.08 | 4 | 9 | 93 | 0.72 |
| Robert LaFromboise | RP | SEA | 6 | 0 | 6.0 | 0 | 0 | 1 | 1 | 7 | 4 | 2 | 3 | 4.50 | 4 | 9 | 93 | 1.83 |
| Zach Putnam | RP | CHC | 11 | 0 | 10.0 | 0 | 0 | 1 | 2 | 14 | 4 | 0 | 4 | 3.60 | 2 | 6 | 92 | 1.60 |
| Mike Ekstrom | RP | OAK | 10 | 0 | 15.0 | 0 | 1 | 3 | 4 | 9 | 2 | 1 | 2 | 1.20 | 4 | 10 | 91 | 0.87 |
| Carter Capps | RP | SEA | 9 | 0 | 9.0 | 0 | 0 | 1 | 1 | 6 | 2 | 0 | 1 | 1.00 | 2 | 13 | 91 | 0.89 |
| Kameron Loe | RP | SEA | 9 | 0 | 12.0 | 1 | 0 | 1 | 2 | 12 | 4 | 0 | 2 | 1.50 | 3 | 16 | 90 | 1.25 |
| Al Alburquerque | RP | DET | 13 | 0 | 13.0 | 0 | 1 | 1 | 2 | 9 | 7 | 2 | 6 | 4.15 | 7 | 18 | 89 | 1.23 |
| Stephen Pryor | RP | SEA | 11 | 0 | 11.0 | 1 | 0 | 1 | 3 | 6 | 3 | 1 | 2 | 1.64 | 3 | 11 | 89 | 0.82 |
| Tanner Scheppers | RP | TEX | 9 | 0 | 10.0 | 1 | 0 | 1 | 2 | 11 | 4 | 0 | 4 | 3.60 | 1 | 6 | 86 | 1.20 |
| Joe Paterson | RP | ARI | 12 | 0 | 10.2 | 0 | 1 | 1 | 2 | 9 | 4 | 2 | 2 | 1.69 | 1 | 10 | 85 | 0.94 |
| Dan Runzler | RP | SF | 10 | 0 | 8.2 | 0 | 0 | 1 | 1 | 7 | 7 | 0 | 7 | 7.27 | 5 | 8 | 84 | 1.38 |
| Josh Collmenter | RP | ARI | 6 | 3 | 15.0 | 0 | 1 | 2 | 2 | 14 | 4 | 0 | 4 | 2.40 | 1 | 11 | 84 | 1.00 |
| Jacob Diekman | RP | PHI | 8 | 0 | 10.0 | 1 | 0 | 1 | 2 | 12 | 5 | 1 | 5 | 4.50 | 4 | 14 | 83 | 1.60 |
| Aaron Crow | RP | KC | 10 | 0 | 10.0 | 0 | 0 | 1 | 3 | 11 | 5 | 1 | 5 | 4.50 | 3 | 12 | 82 | 1.40 |
| Thad Weber | RP | SD | 5 | 0 | 9.2 | 0 | 1 | 1 | 2 | 14 | 7 | 1 | 7 | 6.52 | 3 | 4 | 81 | 1.76 |
| Brayan Villarreal | RP | DET | 12 | 0 | 13.0 | 0 | 1 | 2 | 3 | 10 | 3 | 2 | 3 | 2.08 | 3 | 16 | 79 | 1.00 |
| Scott Rice | RP | NYM | 11 | 0 | 12.1 | 0 | 2 | 1 | 2 | 10 | 4 | 0 | 4 | 2.92 | 3 | 11 | 79 | 1.05 |
| Ryan Mattheus | RP | WAS | 12 | 0 | 13.0 | 2 | 2 | 1 | 2 | 12 | 7 | 1 | 5 | 3.46 | 2 | 16 | 78 | 1.08 |
| Preston Claiborne | RP | NYY | 10 | 0 | 10.2 | 1 | 0 | 1 | 1 | 9 | 1 | 0 | 1 | 0.84 | 3 | 11 | 78 | 1.12 |
| Anthony Varvaro | RP | ATL | 12 | 0 | 12.2 | 1 | 0 | 3 | 3 | 13 | 6 | 0 | 6 | 4.26 | 4 | 11 | 77 | 1.34 |
| Juan Sandoval | RP | TB | 8 | 0 | 9.1 | 0 | 0 | 2 | 4 | 10 | 7 | 1 | 7 | 6.75 | 7 | 7 | 77 | 1.82 |
| Vidal Nuno | SP | NYY | 7 | 2 | 14.2 | 1 | 1 | 1 | 2 | 10 | 1 | 0 | 1 | 0.61 | 4 | 13 | 77 | 0.95 |
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