| Basic Stats | Extended Stats |
| Wins | ||||||||||||||||||
| Player | Pos | Team | GP | GS | IP | W | L | SV | SVO | H | R | HR | ER | ERA | BB | K | TP | WHIP |
| Wily Peralta | SP | MIL | 15 | 15 | 80.0 | 4 | 8 | 0 | 0 | 101 | 63 | 9 | 54 | 6.08 | 32 | 45 | 1346 | 1.66 |
| R.A. Dickey | SP | TOR | 15 | 15 | 93.2 | 6 | 8 | 0 | 0 | 92 | 55 | 14 | 51 | 4.90 | 38 | 67 | 1549 | 1.39 |
| Joe Blanton | SP | LAA | 14 | 14 | 83.1 | 1 | 10 | 0 | 0 | 117 | 55 | 15 | 52 | 5.62 | 16 | 69 | 1373 | 1.60 |
| Edinson Volquez | SP | SD | 15 | 15 | 81.2 | 5 | 5 | 0 | 0 | 94 | 54 | 7 | 53 | 5.84 | 37 | 64 | 1388 | 1.60 |
| Dan Haren | SP | WAS | 14 | 14 | 78.2 | 4 | 8 | 0 | 0 | 98 | 54 | 18 | 50 | 5.72 | 13 | 62 | 1320 | 1.41 |
| Jeremy Hellickson | SP | TB | 14 | 14 | 85.2 | 4 | 3 | 0 | 0 | 89 | 54 | 13 | 54 | 5.67 | 19 | 66 | 1398 | 1.26 |
| Ian Kennedy | SP | ARI | 14 | 14 | 84.2 | 3 | 4 | 0 | 0 | 82 | 51 | 14 | 49 | 5.21 | 29 | 73 | 1414 | 1.31 |
| Jason Hammel | SP | BAL | 14 | 14 | 80.2 | 7 | 4 | 0 | 0 | 91 | 50 | 13 | 47 | 5.24 | 29 | 54 | 1358 | 1.49 |
| Wade Davis | SP | KC | 14 | 14 | 74.2 | 4 | 5 | 0 | 0 | 100 | 50 | 10 | 43 | 5.18 | 30 | 65 | 1370 | 1.74 |
| Mike Pelfrey | SP | MIN | 14 | 14 | 70.2 | 3 | 6 | 0 | 0 | 94 | 50 | 7 | 48 | 6.11 | 21 | 38 | 1270 | 1.63 |
| Edwin Jackson | SP | CHC | 13 | 13 | 71.2 | 3 | 8 | 0 | 0 | 82 | 50 | 5 | 43 | 5.40 | 29 | 71 | 1214 | 1.55 |
| Matt Cain | SP | SF | 15 | 15 | 95.0 | 5 | 3 | 0 | 0 | 78 | 49 | 15 | 48 | 4.55 | 29 | 88 | 1523 | 1.13 |
| Barry Zito | SP | SF | 14 | 14 | 79.0 | 4 | 5 | 0 | 0 | 96 | 49 | 4 | 41 | 4.67 | 30 | 51 | 1362 | 1.59 |
| Wade Miley | SP | ARI | 14 | 14 | 83.1 | 4 | 6 | 0 | 0 | 92 | 49 | 11 | 43 | 4.64 | 27 | 60 | 1313 | 1.43 |
| Cole Hamels | SP | PHI | 15 | 15 | 94.0 | 2 | 10 | 0 | 0 | 91 | 49 | 12 | 46 | 4.40 | 28 | 89 | 1550 | 1.27 |
| CC Sabathia | SP | NYY | 15 | 15 | 103.0 | 7 | 5 | 0 | 0 | 106 | 48 | 14 | 45 | 3.93 | 21 | 89 | 1563 | 1.23 |
| Jon Lester | SP | BOS | 15 | 15 | 94.2 | 6 | 4 | 0 | 0 | 92 | 48 | 11 | 46 | 4.37 | 33 | 80 | 1627 | 1.32 |
| Tim Lincecum | SP | SF | 14 | 14 | 82.2 | 4 | 7 | 0 | 0 | 81 | 48 | 8 | 42 | 4.57 | 39 | 81 | 1388 | 1.45 |
| Mark Buehrle | SP | TOR | 14 | 14 | 87.0 | 3 | 4 | 0 | 0 | 91 | 48 | 12 | 45 | 4.66 | 24 | 58 | 1421 | 1.32 |
| Joe Saunders | SP | SEA | 14 | 14 | 84.1 | 5 | 6 | 0 | 0 | 94 | 46 | 10 | 45 | 4.80 | 27 | 45 | 1357 | 1.43 |
| Roberto Hernandez | SP | TB | 13 | 13 | 75.1 | 4 | 7 | 0 | 0 | 84 | 46 | 12 | 42 | 5.02 | 20 | 65 | 1241 | 1.38 |
| Yovani Gallardo | SP | MIL | 15 | 15 | 87.2 | 6 | 6 | 0 | 0 | 88 | 45 | 9 | 43 | 4.41 | 30 | 69 | 1481 | 1.35 |
| Jarrod Parker | SP | OAK | 15 | 15 | 90.0 | 6 | 6 | 0 | 0 | 83 | 45 | 13 | 43 | 4.30 | 34 | 61 | 1392 | 1.30 |
| Lucas Harrell | SP | HOU | 15 | 15 | 84.1 | 5 | 7 | 0 | 0 | 91 | 45 | 10 | 42 | 4.48 | 41 | 49 | 1514 | 1.57 |
| C.J. Wilson | SP | LAA | 14 | 14 | 87.2 | 5 | 5 | 0 | 0 | 87 | 45 | 8 | 38 | 3.90 | 38 | 82 | 1514 | 1.43 |
| Jon Garland | SP | COL | 12 | 12 | 68.0 | 4 | 6 | 0 | 0 | 85 | 45 | 9 | 44 | 5.82 | 23 | 32 | 1090 | 1.59 |
| Justin Grimm | SP | TEX | 12 | 12 | 67.2 | 5 | 5 | 0 | 0 | 84 | 44 | 9 | 42 | 5.59 | 22 | 55 | 1135 | 1.57 |
| Ryan Vogelsong | SP | SF | 9 | 9 | 46.1 | 2 | 4 | 0 | 0 | 62 | 44 | 11 | 37 | 7.19 | 18 | 40 | 840 | 1.73 |
| Clayton Richard | SP | SD | 11 | 10 | 52.2 | 2 | 5 | 0 | 0 | 65 | 44 | 13 | 41 | 7.01 | 21 | 24 | 852 | 1.63 |
| Ryan Dempster | SP | BOS | 14 | 14 | 83.1 | 4 | 7 | 0 | 0 | 71 | 43 | 15 | 39 | 4.21 | 40 | 87 | 1465 | 1.33 |
| Tim Hudson | SP | ATL | 15 | 15 | 90.2 | 4 | 6 | 0 | 0 | 83 | 43 | 9 | 42 | 4.17 | 22 | 67 | 1404 | 1.16 |
| Jeff Francis | SP | COL | 11 | 11 | 52.0 | 2 | 5 | 0 | 0 | 64 | 43 | 11 | 38 | 6.58 | 17 | 43 | 916 | 1.56 |
| Vance Worley | SP | MIN | 10 | 10 | 48.2 | 1 | 5 | 0 | 0 | 82 | 43 | 9 | 39 | 7.21 | 15 | 25 | 918 | 1.99 |
| Paul Maholm | SP | ATL | 15 | 15 | 93.1 | 7 | 6 | 0 | 0 | 90 | 42 | 9 | 37 | 3.57 | 26 | 69 | 1470 | 1.24 |
| A.J. Griffin | SP | OAK | 14 | 14 | 89.1 | 5 | 6 | 0 | 0 | 83 | 42 | 14 | 39 | 3.93 | 22 | 69 | 1417 | 1.18 |
| Marco Estrada | SP | MIL | 12 | 12 | 69.1 | 4 | 4 | 0 | 0 | 76 | 42 | 14 | 41 | 5.32 | 18 | 62 | 1141 | 1.36 |
| Juan Nicasio | SP | COL | 14 | 14 | 74.0 | 4 | 2 | 0 | 0 | 73 | 42 | 9 | 40 | 4.86 | 27 | 51 | 1284 | 1.35 |
| Dylan Axelrod | SP | CHW | 14 | 14 | 80.0 | 3 | 4 | 0 | 0 | 86 | 42 | 11 | 39 | 4.39 | 27 | 46 | 1356 | 1.41 |
| Jonathon Niese | SP | NYM | 13 | 13 | 73.2 | 3 | 6 | 0 | 0 | 83 | 42 | 5 | 34 | 4.15 | 33 | 44 | 1271 | 1.57 |
| Jeremy Guthrie | SP | KC | 14 | 14 | 92.0 | 7 | 4 | 0 | 0 | 94 | 41 | 19 | 38 | 3.72 | 31 | 44 | 1442 | 1.36 |
| Dillon Gee | SP | NYM | 14 | 14 | 79.0 | 5 | 7 | 0 | 0 | 93 | 41 | 11 | 40 | 4.56 | 21 | 69 | 1284 | 1.44 |
| Bud Norris | SP | HOU | 15 | 15 | 89.0 | 5 | 7 | 0 | 0 | 98 | 41 | 6 | 36 | 3.64 | 28 | 61 | 1428 | 1.42 |
| Scott Diamond | SP | MIN | 12 | 12 | 66.1 | 4 | 6 | 0 | 0 | 84 | 41 | 7 | 39 | 5.29 | 15 | 30 | 1118 | 1.49 |
| Jeff Samardzija | SP | CHC | 15 | 15 | 99.1 | 4 | 7 | 0 | 0 | 84 | 41 | 9 | 37 | 3.35 | 34 | 110 | 1585 | 1.19 |
| Justin Verlander | SP | DET | 15 | 15 | 92.0 | 8 | 5 | 0 | 0 | 92 | 40 | 7 | 38 | 3.72 | 32 | 106 | 1604 | 1.35 |
| Justin Masterson | SP | CLE | 15 | 15 | 102.1 | 8 | 5 | 0 | 0 | 80 | 40 | 8 | 40 | 3.52 | 41 | 102 | 1550 | 1.18 |
| Tommy Milone | SP | OAK | 14 | 14 | 89.2 | 6 | 6 | 0 | 0 | 86 | 40 | 14 | 36 | 3.61 | 19 | 73 | 1438 | 1.17 |
| Ubaldo Jimenez | SP | CLE | 14 | 14 | 73.1 | 5 | 4 | 0 | 0 | 61 | 40 | 10 | 38 | 4.66 | 38 | 71 | 1325 | 1.35 |
| Jhoulys Chacin | SP | COL | 13 | 13 | 80.1 | 5 | 3 | 0 | 0 | 78 | 40 | 2 | 38 | 4.26 | 24 | 48 | 1196 | 1.27 |
| Phil Hughes | SP | NYY | 13 | 13 | 70.0 | 3 | 5 | 0 | 0 | 76 | 40 | 13 | 38 | 4.89 | 22 | 65 | 1237 | 1.40 |
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