| Basic Stats | Extended Stats |
| Wins | ||||||||||||||||||
| Player | Pos | Team | GP | GS | IP | W | L | SV | SVO | H | R | HR | ER | ERA | BB | K | TP | WHIP |
| Luis Mendoza | SP | KC | 12 | 11 | 64.0 | 2 | 3 | 0 | 0 | 67 | 33 | 7 | 29 | 4.08 | 26 | 40 | 1043 | 1.45 |
| David Hernandez | RP | ARI | 29 | 0 | 31.0 | 2 | 4 | 1 | 5 | 27 | 14 | 6 | 14 | 4.06 | 12 | 31 | 511 | 1.26 |
| Brian Duensing | RP | MIN | 33 | 0 | 25.2 | 2 | 1 | 1 | 3 | 27 | 11 | 0 | 11 | 3.86 | 9 | 22 | 395 | 1.40 |
| Kyle Lohse | SP | MIL | 13 | 13 | 79.2 | 2 | 6 | 0 | 0 | 84 | 36 | 13 | 34 | 3.84 | 13 | 49 | 1207 | 1.22 |
| Jim Johnson | RP | BAL | 37 | 0 | 35.1 | 2 | 5 | 26 | 30 | 32 | 16 | 3 | 15 | 3.82 | 8 | 26 | 545 | 1.13 |
| Gerrit Cole | SP | PIT | 2 | 2 | 12.0 | 2 | 0 | 0 | 0 | 14 | 5 | 0 | 5 | 3.75 | 0 | 3 | 161 | 1.17 |
| Matt Guerrier | RP | LAD | 31 | 0 | 27.2 | 2 | 2 | 0 | 1 | 26 | 13 | 3 | 11 | 3.58 | 10 | 21 | 422 | 1.30 |
| Cory Gearrin | RP | ATL | 33 | 0 | 28.1 | 2 | 1 | 1 | 3 | 27 | 11 | 2 | 11 | 3.49 | 11 | 19 | 433 | 1.34 |
| Tyler Cloyd | SP | PHI | 6 | 6 | 34.1 | 2 | 2 | 0 | 0 | 37 | 14 | 2 | 13 | 3.41 | 15 | 18 | 582 | 1.51 |
| Brandon Lyon | RP | NYM | 30 | 0 | 26.2 | 2 | 2 | 0 | 2 | 28 | 11 | 2 | 10 | 3.38 | 8 | 19 | 425 | 1.35 |
| Addison Reed | RP | CHW | 30 | 0 | 32.0 | 2 | 0 | 20 | 22 | 24 | 12 | 2 | 12 | 3.38 | 9 | 36 | 514 | 1.03 |
| Hector Santiago | RP | CHW | 18 | 7 | 57.1 | 2 | 5 | 0 | 0 | 47 | 26 | 6 | 21 | 3.30 | 30 | 60 | 1049 | 1.34 |
| P.J. Walters | SP | MIN | 5 | 5 | 30.2 | 2 | 2 | 0 | 0 | 40 | 15 | 3 | 11 | 3.23 | 9 | 18 | 484 | 1.60 |
| Jordan Walden | RP | ATL | 22 | 0 | 20.0 | 2 | 1 | 0 | 0 | 18 | 7 | 0 | 7 | 3.15 | 4 | 22 | 335 | 1.10 |
| Chad Qualls | RP | MIA | 26 | 0 | 26.1 | 2 | 0 | 0 | 0 | 25 | 9 | 2 | 9 | 3.08 | 7 | 19 | 350 | 1.22 |
| Jeanmar Gomez | SP | PIT | 12 | 7 | 44.0 | 2 | 0 | 0 | 0 | 35 | 17 | 5 | 15 | 3.07 | 16 | 23 | 656 | 1.16 |
| Ross Detwiler | SP | WAS | 9 | 9 | 50.2 | 2 | 4 | 0 | 0 | 62 | 19 | 3 | 17 | 3.02 | 10 | 25 | 769 | 1.42 |
| Antonio Bastardo | RP | PHI | 30 | 0 | 24.0 | 2 | 2 | 1 | 4 | 23 | 9 | 2 | 8 | 3.00 | 14 | 22 | 415 | 1.54 |
| Andrew Bailey | RP | BOS | 22 | 0 | 21.1 | 2 | 0 | 8 | 10 | 16 | 7 | 4 | 7 | 2.95 | 9 | 30 | 376 | 1.17 |
| Justin De Fratus | RP | PHI | 17 | 0 | 12.1 | 2 | 0 | 0 | 0 | 9 | 4 | 1 | 4 | 2.92 | 3 | 10 | 193 | 0.97 |
| Josh Roenicke | RP | MIN | 27 | 0 | 31.2 | 2 | 1 | 0 | 1 | 25 | 10 | 4 | 10 | 2.84 | 16 | 21 | 522 | 1.29 |
| Chad Gaudin | RP | SF | 21 | 3 | 47.2 | 2 | 1 | 0 | 0 | 41 | 15 | 4 | 15 | 2.83 | 16 | 40 | 754 | 1.20 |
| Matt Lindstrom | RP | CHW | 35 | 0 | 28.2 | 2 | 2 | 0 | 2 | 24 | 9 | 0 | 9 | 2.83 | 15 | 20 | 440 | 1.36 |
| James Shields | SP | KC | 15 | 15 | 106.0 | 2 | 6 | 0 | 0 | 89 | 33 | 9 | 32 | 2.72 | 30 | 95 | 1627 | 1.12 |
| Darren Oliver | RP | TOR | 20 | 0 | 20.0 | 2 | 1 | 0 | 1 | 20 | 9 | 2 | 6 | 2.70 | 7 | 12 | 291 | 1.35 |
| Mike Dunn | RP | MIA | 35 | 0 | 30.2 | 2 | 1 | 1 | 2 | 26 | 9 | 1 | 9 | 2.64 | 18 | 31 | 543 | 1.43 |
| J.P. Howell | RP | LAD | 28 | 0 | 31.2 | 2 | 0 | 0 | 0 | 22 | 8 | 1 | 8 | 2.27 | 12 | 27 | 499 | 1.07 |
| Joe Thatcher | RP | SD | 35 | 0 | 20.0 | 2 | 1 | 0 | 1 | 22 | 5 | 2 | 5 | 2.25 | 2 | 19 | 349 | 1.20 |
| Tim Collins | RP | KC | 28 | 0 | 24.2 | 2 | 1 | 0 | 2 | 18 | 7 | 0 | 6 | 2.19 | 13 | 24 | 437 | 1.26 |
| Greg Holland | RP | KC | 27 | 0 | 26.0 | 2 | 1 | 15 | 17 | 18 | 8 | 1 | 6 | 2.08 | 11 | 41 | 457 | 1.12 |
| Jake Westbrook | SP | STL | 7 | 7 | 44.0 | 2 | 2 | 0 | 0 | 47 | 14 | 0 | 10 | 2.05 | 19 | 19 | 691 | 1.50 |
| Cody Allen | RP | CLE | 29 | 0 | 31.0 | 2 | 0 | 1 | 2 | 21 | 9 | 2 | 7 | 2.03 | 10 | 39 | 501 | 1.00 |
| Luis Avilan | RP | ATL | 33 | 0 | 27.1 | 2 | 0 | 0 | 0 | 17 | 7 | 0 | 6 | 1.98 | 12 | 15 | 447 | 1.06 |
| Drew Smyly | RP | DET | 24 | 0 | 41.2 | 2 | 0 | 2 | 3 | 30 | 9 | 1 | 9 | 1.94 | 12 | 42 | 703 | 1.01 |
| Craig Breslow | RP | BOS | 20 | 0 | 19.1 | 2 | 1 | 0 | 0 | 13 | 5 | 0 | 4 | 1.86 | 6 | 12 | 283 | 0.98 |
| Craig Kimbrel | RP | ATL | 27 | 0 | 26.1 | 2 | 1 | 19 | 22 | 20 | 5 | 3 | 5 | 1.71 | 7 | 37 | 405 | 1.03 |
| Jim Henderson | RP | MIL | 23 | 0 | 22.2 | 2 | 2 | 9 | 10 | 15 | 4 | 1 | 4 | 1.59 | 5 | 26 | 376 | 0.88 |
| Boone Logan | RP | NYY | 28 | 0 | 18.2 | 2 | 2 | 0 | 0 | 17 | 4 | 2 | 3 | 1.45 | 4 | 27 | 299 | 1.12 |
| Michael Stutes | RP | PHI | 11 | 0 | 13.2 | 2 | 0 | 0 | 0 | 10 | 3 | 0 | 2 | 1.32 | 2 | 6 | 190 | 0.88 |
| Ryan Pressly | RP | MIN | 21 | 0 | 30.0 | 2 | 0 | 0 | 0 | 22 | 8 | 0 | 4 | 1.20 | 12 | 23 | 463 | 1.13 |
| Kevin Gregg | RP | CHC | 22 | 0 | 21.2 | 2 | 0 | 9 | 9 | 14 | 3 | 1 | 2 | 0.83 | 7 | 24 | 389 | 0.97 |
| Rex Brothers | RP | COL | 33 | 0 | 30.0 | 2 | 0 | 3 | 4 | 20 | 1 | 0 | 1 | 0.30 | 16 | 29 | 472 | 1.20 |
| Alex Torres | RP | TB | 8 | 0 | 16.0 | 2 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0.00 | 3 | 23 | 202 | 0.38 |
| Mark Lowe | RP | LAA | 11 | 0 | 11.2 | 1 | 0 | 0 | 0 | 11 | 12 | 1 | 12 | 9.26 | 11 | 7 | 247 | 1.89 |
| Michael Roth | RP | LAA | 9 | 1 | 14.0 | 1 | 1 | 0 | 0 | 21 | 14 | 0 | 14 | 9.00 | 3 | 14 | 251 | 1.71 |
| Derek Lowe | RP | TEX | 9 | 0 | 13.0 | 1 | 0 | 0 | 0 | 16 | 13 | 3 | 13 | 9.00 | 3 | 8 | 199 | 1.46 |
| Chad Durbin | RP | PHI | 16 | 0 | 16.0 | 1 | 0 | 0 | 0 | 25 | 17 | 4 | 16 | 9.00 | 9 | 16 | 329 | 2.12 |
| Zach Duke | RP | WAS | 12 | 1 | 20.2 | 1 | 1 | 0 | 0 | 31 | 22 | 2 | 20 | 8.71 | 8 | 11 | 336 | 1.89 |
| Donnie Veal | RP | CHW | 14 | 0 | 7.1 | 1 | 0 | 0 | 0 | 11 | 8 | 1 | 7 | 8.59 | 9 | 5 | 165 | 2.73 |
| Steve Johnson | RP | BAL | 5 | 1 | 11.2 | 1 | 1 | 0 | 0 | 13 | 11 | 2 | 11 | 8.49 | 8 | 15 | 229 | 1.80 |
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