CBSSports.com baseball staff make their 2008 picks:
| American League East |
| Place | Miller | Cimilluca | Mack | Gonos | Rosen |
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| American League Central |
| Place | Miller | Cimilluca | Mack | Gonos | Rosen |
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| American League West |
| Place | Miller | Cimilluca | Mack | Gonos | Rosen |
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| American League Wild Card |
| Miller | Cimilluca | Mack | Gonos | Rosen |
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| American League Champion |
| Miller | Cimilluca | Mack | Gonos | Rosen |
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| American League Awards/Miscellany |
| Miller | Cimilluca | Mack | Gonos | Rosen | |
| MVP | M. Cabrera, DET | M. Cabrera, DET | M. Cabrera, DET | M. Cabrera, DET | M. Cabrera, DET |
| Cy Young | E. Bedard, SEA | J. Beckett, BOS | J. Verlander, DET | J. Verlander, DET | J. Beckett, BOS |
| Rookie | E. Longoria, TB | E. Longoria, TB | E. Longoria, TB | E. Longoria, TB | D. Barton, OAK |
| Manager | J. McLaren, SEA | B. Geren, OAK | J. Leyland, DET | J. Gibbons, TOR | J. McLaren, SEA |
| Comeback | V. Wells, TOR | H. Blalock, TEX | B. Crosby, OAK | G. Sheffield, DET | R. Sexson, SEA |
| HR Champ | A. Rodriguez, NYY | A. Rodriguez, NYY | A. Rodriguez, NYY | A. Rodriguez, NYY | A. Rodriguez, NYY |
| Surprise | S. Baker, MIN | K. Millar, BAL | A. Gordon, KC | A. Hill, TOR | E. Aybar, ANA |
| Disappointment | D. Willis, DET | O. Cabrera, CHW | H. Matsui, NYY | D. Pedroia, BOS | J. Lugo, BOS |
| National League East |
| Place | Miller | Cimilluca | Mack | Gonos | Rosen |
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| National League Central |
| Place | Miller | Cimilluca | Mack | Gonos | Rosen |
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| National League West |
