Carmona hit a grounder to third baseman Scott Rolen with a runner aboard in the top of the third. Running hard to try to avoid an out, he tripped a few steps shy of first base and fell on his chest. Carmona got up, stretched his right thigh and shook his pitching hand.
After talking to manager Manny Acta, he left the game. He was diagnosed with a strained right thigh. There was no immediate indication how long he would be sidelined.
Carmona was the Indians' only All-Star last season. He's been in a deep slump, falling to 4-10.