Madson will have Tommy John surgery, so he is done for the season without ever throwing a pitch.
"It's obviously not great news," Reds general manager Walt Jocketty said. "We talked to the team and told them that we all have to stay positive. We have alternatives internally that we can turn to.
"A lot of clubs have done that in the past. I did it in St. Louis when (Jason) Isringhausen went down. (Adam) Wainwright stepped up and we won a World Series. Arizona's done it. A lot of clubs have done it."
Left-hander Sean Marshall will move into the closer role, despite the fact that he has seven career saves in six big-league seasons.
The Madson news shook up what had been a very smooth spring training.
"I've got more range of motion than I've had in four or five years," said Rolen, who had a fourth surgery on left shoulder in Aug. 3. He was hitting .325 and slugging .538 going into the final three games of the spring.
Cozart, who had left elbow surgery, was hitting .392. That included an eight-game hitting streak in which he hit .650.
The Reds settled on Bailey as the fifth starter as camp wound down. Left-hander Aroldis Chapman, who pitched extremely well in camp, was sent back to the bullpen, where he was effective the last two years.
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