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| Team Ranking | AVG | R | HR | ERA |
| Red Sox | .27 | 240 | 57 | 4.69 |
| East Division | 1st | 1st | 4th | 5th |
| American League | 2nd | 2nd | 5th | 12th |
| Roster | ||||||||
| No | STARTERS | AGE | B | T | HT | WT | DOB | 2012 SALARY |
| 51 | Bard, Daniel | 26 | R | R | 6-4 | 200 | 06/25/1985 | $1,612,500 |
| 19 | Beckett, Josh | 32 | R | R | 6-5 | 225 | 05/15/1980 | $17,000,000 |
| 11 | Buchholz, Clay | 27 | L | R | 6-3 | 190 | 08/14/1984 | $3,750,000 |
| 35 | Cook, Aaron (DL) | 33 | R | R | 6-3 | 215 | 02/08/1979 | Not available |
| 61 | Doubront, Felix | 24 | L | L | 6-2 | 165 | 10/23/1987 | $484,000 |
| 41 | Lackey, John (DL) | 33 | R | R | 6-6 | 245 | 10/23/1978 | $15,950,000 |
| 31 | Lester, Jon | 28 | L | L | 6-4 | 240 | 01/07/1984 | $7,625,000 |
| 18 | Matsuzaka, Daisuke (DL) | 31 | R | R | 6-0 | 185 | 09/13/1980 | $10,333,333 |
| No | BULLPEN | AGE | B | T | HT | WT | DOB | 2012 SALARY |
| 91 | Aceves, Alfredo | 29 | R | R | 6-3 | 220 | 12/08/1982 | $1,200,000 |
| 32 | Albers, Matt | 29 | L | R | 6-0 | 225 | 01/20/1983 | $1,075,000 |
| 48 | Atchison, Scott | 36 | R | R | 6-2 | 200 | 03/29/1976 | $510,000 |
| 40 | Bailey, Andrew (DL) | 27 | R | R | 6-3 | 240 | 05/31/1984 | $3,900,000 |
| 66 | Carpenter, Chris (DL) | 26 | 6-4 | 220 | 12/26/1985 | $482,000 | ||
| 53 | Hill, Rich | 32 | L | L | 6-5 | 220 | 03/11/1980 | $725,000 |
| 52 | Jenks, Bobby (DL) | 31 | R | R | 6-4 | 275 | 03/14/1981 | $6,000,000 |
| 30 | Miller, Andrew | 27 | L | L | 6-7 | 210 | 05/21/1985 | $1,040,000 |
| 46 | Morales, Franklin | 26 | L | L | 6-0 | 210 | 01/24/1986 | $850,000 |
| 44 | Padilla, Vicente | 34 | R | R | 6-0 | 230 | 09/27/1977 | $1,500,000 |
| No | CATCHERS | AGE | B | T | HT | WT | DOB | 2012 SALARY |
| 39 | Saltalamacchia, Jarrod | 27 | S | R | 6-4 | 235 | 05/02/1985 | $2,500,000 |
| 10 | Shoppach, Kelly | 32 | R | R | 6-0 | 220 | 04/29/1980 | $1,350,000 |
| No | INFIELDERS | AGE | B | T | HT | WT | DOB | 2012 SALARY |
| 3 | Aviles, Mike | 31 | R | R | 5-10 | 205 | 03/13/1981 | $1,200,000 |
| 28 | Gonzalez, Adrian | 30 | L | L | 6-2 | 225 | 05/08/1982 | $21,857,142 |
| 64 | Middlebrooks, Will | 23 | 6-4 | 200 | 09/09/1988 | Not available | ||
| 15 | Pedroia, Dustin | 28 | R | R | 5-9 | 180 | 08/17/1983 | $8,250,000 |
| 5 | Punto, Nick | 34 | S | R | 5-9 | 190 | 11/08/1977 | $1,500,000 |
| 20 | Youkilis, Kevin | 33 | R | R | 6-1 | 220 | 03/15/1979 | $12,250,000 |
| No | OUTFIELDERS | AGE | B | T | HT | WT | DOB | 2012 SALARY |
| 23 | Byrd, Marlon | 34 | R | R | 6-0 | 245 | 08/30/1977 | $6,500,000 |
| 13 | Crawford, Carl (DL) | 30 | L | L | 6-2 | 215 | 08/05/1981 | $20,357,142 |
| 2 | Ellsbury, Jacoby (DL) | 28 | L | L | 6-1 | 185 | 09/11/1983 | $8,050,000 |
| 55 | Kalish, Ryan (DL) | 24 | L | L | 6-1 | 205 | 03/28/1988 | $483,000 |
| 67 | Lin, Che-Hsuan | 23 | R | R | 6-0 | 180 | 09/21/1988 | Not available |
| 54 | McDonald, Darnell (DL) | 33 | R | R | 5-11 | 205 | 11/17/1978 | $506,500 |
| 66 | Nava, Daniel | 29 | S | L | 5-10 | 200 | 02/22/1983 | Not available |
| 26 | Podsednik, Scott | 36 | L | L | 6-1 | 190 | 03/18/1976 | Not available |
| 16 | Repko, Jason (DL) | 31 | R | R | 5-11 | 200 | 12/27/1980 | Not available |
| 7 | Ross, Cody (DL) | 31 | R | L | 5-10 | 195 | 12/23/1980 | $3,000,000 |
| 12 | Sweeney, Ryan (DL) | 27 | L | L | 6-4 | 225 | 02/20/1985 | $1,750,000 |
| No | DESIGNATED HITTERS | AGE | B | T | HT | WT | DOB | 2012 SALARY |
| 34 | Ortiz, David | 36 | L | L | 6-4 | 230 | 11/18/1975 | $14,575,000 |
