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| Team Ranking | AVG | R | HR | ERA |
| Padres | .224 | 151 | 18 | 3.61 |
| West Division | 4th | 5th | 4th | 3rd |
| National League | 11th | 14th | 13th | 7th |
| Date | Opponent | Time/Result |
| Mar 4 | @Seattle | Lost 4-5 |
| Mar 5 | Seattle | Lost 7-13 |
| Mar 6 | @Kansas City | Lost 4-7 |
| Mar 7 | @Cincinnati | Won 5-0 |
| Mar 7 | Texas | Lost 2-6 |
| Mar 8 | San Francisco | Lost 2-5 |
| Mar 9 | @L.A. Angels | Won 6-3 |
| Mar 10 | @Cleveland | Won 5-2 |
| Mar 11 | Arizona | Lost 7-8 |
| Mar 12 | @Colorado | Lost 2-11 |
| Mar 13 | Chi. White Sox | Won 6-3 |
| Mar 14 | @Cincinnati | Won 9-4 |
| Mar 14 | @Arizona | Won 8-0 |
| Mar 15 | @Milwaukee | Lost 4-6 |
| Mar 16 | L.A. Angels | Won 8-7 |
| Mar 17 | Kansas City | Won 8-5 |
| Mar 18 | @San Francisco | Won 5-1 |
| Mar 20 | Colorado | Won 10-6 |
| Mar 21 | @L.A. Dodgers | Won 3-0 |
| Mar 22 | Cleveland | Lost 4-9 |
| Mar 22 | Colorado | Won 11-6 |
| Mar 23 | Cincinnati | Won 5-2 |
| Mar 24 | Cincinnati | Lost 0-6 |
| Mar 24 | @Chi. Cubs | Won 5-1 |
| Mar 25 | Arizona | Won 4-3 |
| Mar 26 | @Chi. Cubs | Lost 0-2 |
| Mar 27 | @Texas | Lost 9-10 |
| Mar 27 | L.A. Dodgers | Won 6-5 |
| Mar 28 | @Chi. White Sox | Won 13-2 |
| Mar 29 | Chi. Cubs | Won 12-11 |
| Mar 30 | San Francisco | Won 8-7 |
| Mar 31 | Milwaukee | Lost 7-10 |
| Mar 31 | @Seattle | Lost 1-6 |
| Apr 1 | @Texas | Lost 3-5 |
| Apr 3 | Kansas City | Won 2-1 |
| Apr 4 | Kansas City | Lost 6-7 |
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