The Pistons, meanwhile, are without coach Lawrence Frank, who is missing the game because of a personal matter.
Anthony stumbled near midcourt Monday night against Cleveland after catching a pass and fell awkwardly to the floor. He got up, and appearing more embarrassed than hurt, immediately headed to the locker room with a slight limp. He did not return.
The Knicks are playing the first of back-to-back games. They host Oklahoma City on Thursday.
Detroit's Greg Monroe is also out because of a sore left ankle. Assistant coach Brian Hill is taking over for Frank.