The Hillsborough County Sheriff's Office confirmed to WSTV that Williams was stabbed in the thigh and receiving medical care. Williams brother is the primary suspect in the stabbing.
The Hillsborough spokeswoman would not release the brother's name but said that police are looking for him on Sunday evening after the Sunday afternoon stabbing.
Williams 2013 season ended early thanks to a torn hamstring but his offseason since has gone much worse.
His neighbors have since complained that Williams threw loud house parties and at least one neighbor said they "despise" him.
New coach Lovie Smith was not happy about Williams recent behavior when speaking at the 2014 NFL Combine.
"There's a pattern here and it's disturbing," Smith said. "No one is bigger than this football team. He has to understand that.
"Have I been disappointed in Mike Williams? Of course, there's a standard. We're just not going to put up with it, no matter who it is. You have to be good on the field and off the field. Simple as that. And if you're not doing what you need to do one or the other, you have problems and that's where Mike has to take care of a few things."
Williams recently pled not guilty to the charges.
"We are aware of the situation that occurred at the residence of Mike Williams and are working with him and the authorities to get additional information," the statement read. "While we have limited knowledge at this time, our primary concern is for the safety and well bring of all involved. We will refrain from further comment until we can get a better understanding of the situation."