Game Information

• Time: 8:30 PM ET

• TV: CBS
• Surface: Grass

• Prediction: Broncos 27 - 17

Keys to the Game
The Steelers don't want Denver's pass rush to be a major factor, so RB Rashard Mendenhall will get plenty of work early. The Broncos struggled to slow Baltimore's running game... More Series Notes
21st regular-season meeting. Denver leads series 13-6-1. The Broncos are 7-2-1 at home vs. Pittsburgh. The teams are 3-3 in the playoffs. The Steelers have not won in Denver in the regular season since 1990, including a 31-28 loss in 2007. However, Pittsburgh did win the AFC Championship Game in Denver after the 2005 season.

Game Information

• Time: 1:00 PM ET

• TV: FOX
• Surface: Grass

• Prediction: Packers 30 - 13

• Weather: Passing clouds. Warm. 87° F. 12mph wind

Keys to the Game
The Bucs' best chance to be competitive is through a strong pass rush. Problem is, they have only 11 sacks on the season. Packers QB Aaron Rodgers is expected to... More Series Notes
51st regular-season meeting. Packers lead series, 29-20-1. The Buccaneers have won the past two encounters, including 30-21 at Tampa Bay last season, and six of the last nine meetings dating to 1999. Tampa Bay owns a 6-1 home record in the series since Raymond James Stadium opened in 1998. The former division rivals' only postseason matchup was in a 1997 NFC divisional playoff, which the Packers won 21-7 at Green Bay.

Game Information

• Time: 1:00 PM ET

• TV: FOX
• Surface: FieldTurf

• Prediction: Falcons 34 - 10

• Weather: Passing clouds. Mild. 74° F. 4mph wind

Keys to the Game
The Falcons' cornerbacks have struggled in man coverage, but that hasn't stopped them from blitzing more frequently to step up their pass rush. With the Redskins' issues in pass protection... More Series Notes
21st regular-season meeting. Redskins lead 14-5-1 not counting their 1991 playoff victory that provided the most memorable matchup. Known as "The Seat Cushion Game" in Washington, the Redskins humbled Deion Sanders and the cocky, young Falcons 24-7 with a dominating performance in the rain at RFK Stadium. The fans celebrated by flinging their seat cushions onto the field as the Redskins advanced to the NFC Championship Game.

Game Information

• Time: 1:00 PM ET

• TV: CBS
• Surface: Grass

• Prediction: Patriots 28 - 20

• Weather: More sun than clouds. Cool. 61° F. 6mph wind

Keys to the Game
The Dolphins will start three rookies in their secondary against the league's second-ranked passing attack. That means a whole lot of RBs Ronnie Brown and Ricky Williams on offense. As... More Series Notes
85th regular-season meeting. Dolphins lead series 48-36, not including 1-2 mark in the postseason. The Patriots have won 10 of the last 15 meetings but last year Miami snapped New England's 21-game regular-season winning streak with a 38-13 victory in Foxboro when they unleashed the Wildcat on an unsuspecting Patriots' defense and gained 461 yards. The Patriots won the rematch in Miami 48-28 with Matt Cassel throwing for 415 yards and 3 TDs.

Game Information

• Time: 1:00 PM ET

• TV: CBS
• Surface: Grass

• Prediction: Jaguars 19 - 14

• Weather: Passing clouds. Mild. 77° F. 14mph wind

Keys to the Game
Chiefs RB Jamaal Charles gets the start in place of suspended Larry Johnson. He lacks experience and has been in and out of coach Todd Haley's doghouse, but he does... More Series Notes
8th regular-season meeting. Jaguars lead series 5-2. The last game between these teams was played during the 2007 season, when the Jaguars grabbed a 17-7 victory at Arrowhead. The last Chiefs victory was the 2006 regular-season finale, a 35-30 outcome that combined with several other results vaulted Kansas City into the playoffs.

Game Information

• Time: 1:00 PM ET

• TV: FOX
• Surface: Grass

• Prediction: Bears 28 - 24

• Weather: Scattered clouds. Mild. 64° F. 10mph wind

Keys to the Game
Cardinals QB Kurt Warner is coming off a six-turnover game and has been impatient of late with defenses playing back in a lot of deep coverages. It would help to... More Series Notes
88th regular-season meeting. The Bears lead 55-26-6 and have won the last three. The teams last met in 2006 and, in Arizona, the game is known as The Monday Night Meltdown. The Cardinals (1-4) at the time led the undefeated Bears, 23-3. But they let the Bears score three touchdowns in the final quarter to lose, 24-23. That touched off former coach Dennis Green's famous post-game rant. "You want to crown them, go ahead and crown their asses," he said, his voice rising. "But they are exactly who we thought they are, and we let them off the hook."

Game Information

• Time: 1:00 PM ET

• TV: CBS
• Surface: Grass

• Prediction: Bengals 29 - 27

Keys to the Game
The Bengals give up a lot of passing yards (253.3 per game) but not many points (18.3) in a classic bend-don't-break approach. Cincinnati's strength is in containing the run, and... More Series Notes
28th regular-season meeting. Ravens lead series 15-12. The Ravens had lost three straight at Cincinnati before winning there last season. The Ravens lost the earlier meeting with the Bengals last month, 17-14. With the help of three defensive penalties by the Ravens, Cincinnati drove 80 yards down the field in the final two minutes. Andre Caldwell's 20-yard touchdown catch won the game with 22 seconds remaining.

Game Information

• Time: 1:00 PM ET

• TV: CBS
• Surface: FieldTurf

• Prediction: Colts 31 - 20

• Weather: Scattered clouds. Mild. 66° F. 10mph wind

Keys to the Game
QB Peyton Manning didn't throw a single touchdown pass as Indianapolis settled for four field goals last Sunday. That could spell trouble against an opponent with its own impressive offensive... More Series Notes
15th regular-season meeting. Colts lead series 13-1, including 7-0 in Indianapolis. The closest the Texans have come to winning at Indianapolis was a 33-27 defeat last season when the Colts played at Lucas Oil Stadium for the first time.

Game Information

• Time: 4:05 PM ET

• TV: FOX
• Surface: Sportexe Momentum

• Prediction: Saints 34 - 10

• Weather: Sprinkles late. Afternoon clouds. Mild. 76° F. 14mph wind

Keys to the Game
Panthers DE Julius Peppers has 6.0 sacks in the past four games and must continue his dominating play for Carolina's defense to be effective. New Orleans' improved ground game only... More Series Notes
29th regular-season meeting. Panthers lead series 16-12. The Panthers have never lost on the road at New Orleans since coach John Fox came aboard in 2002. They are 7-0 overall there, including 6-0 at the Superdome and 1-0 at LSU's Tiger Stadium. Jake Delhomme is 6-0 as a starting quarterback at the Superdome during his career. In last year's regular-season finale, the Panthers defeated the Saints 33-31 to capture the NFC South division championship.

Game Information

• Time: 4:05 PM ET

• TV: FOX
• Surface: FieldTurf

• Prediction: Seahawks 24 - 13

• Weather: Rain. Overcast. Cool. 51° F. 7mph wind

Keys to the Game
Former Seahawk RB Maurice Morris could play a big role. Lions starter Kevin Smith is expected to play, but does have a shoulder injury and Morris provided a lift in... More Series Notes
11th regular-season meeting. Seahawks lead series, 6-4. The Seahawks won the last meeting, 9-6, but it was a bit of a moral victory for the Lions. It was the Seahawks' first real game since playing Super Bowl XL in the Lions' home stadium, Ford Field.

Game Information

• Time: 4:15 PM ET

• TV: CBS
• Surface: Grass

• Prediction: 49ers 28 - 16

• Weather: Passing clouds. Mild. 63° F. 15mph wind

Keys to the Game
QB Vince Young displayed poise in his first start of the season last week. Of course, it's easy to lead an offense that rushes for 305 yards. If San Francisco's... More Series Notes
12th regular-season meeting. 49ers lead series 7-4. Tennessee won 33-22 the last time these two teams met at LP Field in 2005.

Game Information

• Time: 4:15 PM ET

• TV: CBS
• Surface: FieldTurf

• Prediction: Chargers 17 - 16

• Weather: More sun than clouds. Mild. 65° F. 7mph wind

Keys to the Game
The Chargers have slowly gotten RB LaDainian Tomlinson more involved, but this is a matchup for QB Philip Rivers to exploit. The Giants have given up 112 points over the... More Series Notes
10th regular-season meeting. Giants lead series 5-4, but the Chargers won the last game, 45-23, in San Diego in 2005. The Chargers' last visit to New Jersey came in 1995 where they needed to win to secure a playoff spot. The game was marred by the Chargers being buried by a barrage of snowballs.

Game Information

• Time: 8:20 PM ET

• TV: NBC
• Surface: Grass

• Prediction: Eagles 30 - 28

• Weather: Passing clouds. Mild. 63° F. 8mph wind

Keys to the Game
QB Tony Romo might not be on the same page with WR Roy Williams, but that is about the only thing not clicking with Dallas' offense. A trio of running... More Series Notes
97th regular-season meeting. Dallas leads the series 53-43. The Eagles won the last meeting 44-6 at Philadelphia. The Eagles have won four of the last six games. The Eagles have beaten the Cowboys by double digits 10 times since 2000. Eight times the Eagles have beaten the Cowboys by 20 points.