| Passing | ||||
| CP/AT | YDS | TD | INT | |
| A. Smith | 9/15 | 113 | 1 | 0 |
| D. Carr | 7/17 | 54 | 0 | 0 |
| Rushing | ||||
| ATT | YDS | TD | LG | |
| A. Dixon | 21 | 69 | 1 | 9 |
| F. Gore | 2 | 58 | 0 | 49 |
| B. Westbrook | 2 | 17 | 0 | 17 |
| D. Carr | 2 | 8 | 0 | 5 |
| J. Caulcrick | 2 | 8 | 0 | 4 |
| M. Robinson | 1 | 3 | 0 | 3 |
| M. Norris | 2 | 2 | 0 | 2 |
| A. Smith | 1 | 0 | 0 | 0 |
| Receiving | ||||
| REC | YDS | TD | LG | |
| D. Zeigler | 5 | 47 | 0 | 12 |
| D. Walker | 1 | 38 | 0 | 38 |
| J. Morgan | 3 | 31 | 1 | 16 |
| M. Norris | 2 | 21 | 0 | 13 |
| A. Dixon | 3 | 15 | 0 | 7 |
| T. Ginn Jr. | 1 | 9 | 0 | 9 |
| N. Byham | 1 | 6 | 0 | 6 |
| Fumbles | ||||
| NO | LST | REC | YDS | |
| A. Smith | 1 | 0 | 0 | -3 |
| F. Gore | 0 | 0 | 1 | 0 |
| Kicking | ||||
| FG | LG | XP | PTS | |
| J. Nedney | 1/2 | 0 | 2/2 | 5 |
| S. Andrus | 1/1 | 38 | 0/0 | 3 |
| Punting | ||||
| NO | AVG | I20 | LG | |
| A. Lee | 4 | 48.0 | 2 | 54 |
| Kickoff Returns | ||||
| NO | AVG | TD | LG | |
| B. Guillory | 2 | 15.5 | 0 | 17 |
| K. Jurovich | 1 | 48.0 | 0 | 48 |
| Punt Returns | ||||
| NO | AVG | TD | LG | |
| P. Adams | 3 | 38.7 | 1 | 83 |
| Defense | ||||
| T-A | SCK | INT | FF | |
| P. Willis | 7-1 | 1.0 | 0 | 0 |
| K. Paymah | 5-0 | 0.0 | 0 | 0 |
| N. Bowman | 2-0 | 0.0 | 0 | 0 |
| T. Spikes | 2-1 | 0.0 | 0 | 0 |
| M. Lewis | 2-1 | 0.0 | 0 | 0 |
| T. Mays | 2-0 | 0.0 | 0 | 0 |
| J. Smith | 2-0 | 0.0 | 0 | 0 |
| D. Goldson | 2-0 | 0.0 | 0 | 0 |
| M. Lawson | 2-0 | 0.0 | 0 | 0 |
| K. Kristick | 1-2 | 0.0 | 0 | 0 |
| N. Clements | 1-0 | 0.0 | 0 | 0 |
| R. Smith | 1-0 | 0.0 | 0 | 0 |
| P. Haralson | 1-0 | 0.0 | 0 | 0 |
| T. LaBoy | 1-0 | 1.0 | 0 | 0 |
| W. Tukuafu | 1-0 | 0.0 | 0 | 0 |
| P. Adams | 1-1 | 0.0 | 0 | 0 |
| T. Brown | 0-1 | 0.0 | 0 | 0 |
| I. Sopoaga | 0-1 | 0.0 | 0 | 0 |
|
|
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| 4th Quarter | |
| Oakland at 1:34 | |
| 2-10-OAK 26 | (1:34) (Shotgun) B.Gradkowski pass incomplete deep right to T.Watkins. PENALTY on SF-K.Paymah, Defensive Pass Interference, 33 yards, enforced at OAK 26 - No Play. |
| 1-10-SF 41 | (1:28) (Shotgun) B.Gradkowski pass short right to B.Myers to SF 40 for 1 yard (K.Paymah). |
| 2-9-SF 40 | (1:23) (Shotgun) B.Gradkowski pass incomplete short left to J.Ford. |
| 3-9-SF 40 | (1:19) (Shotgun) B.Gradkowski pass incomplete deep left to Y.Figurs. |
| 4-9-SF 40 | (1:14) (Shotgun) B.Gradkowski pass incomplete deep middle to T.Watkins (R.Smith). |
| San Francisco at 1:07 | |
| 1-10-SF 40 | (1:07) J.Caulcrick up the middle to SF 44 for 4 yards (Team). |
| 2-6-SF 44 | (1:00) A.Dixon right end to SF 41 for -3 yards (S.Norris). |
| 3-9-SF 41 | (:54) (Shotgun) A.Dixon up the middle to SF 42 for 1 yard (T.Goethel). |
| 4-8-SF 42 | (:54) (Punt formation) PENALTY on SF-A.Lee, Delay of Game, 5 yards, enforced at SF 42 - No Play. |
| 4-13-SF 37 | (:06) A.Lee punts 49 yards to OAK 14, Center-B.Jennings, fair catch by N.Miller. |
| 1st Quarter | ||
| TD | Michael Bush, 1 Yd run (Sebastian Janikowski kick is good), 9:37. Drive: 8 plays, 81 yards in 5:23. | |
| 2nd Quarter | ||
| FG | Joe Nedney, 28 Yd, 11:23. Drive: 9 plays, 55 yards in 3:50. | |
| TD | Phillip Adams, 83 Yd punt return (Joe Nedney kick is good), 9:41. | |
| TD | Josh Morgan, 16 Yd pass from Alex Smith (Joe Nedney kick is good), 1:13. Drive: 10 plays, 60 yards in 6:54. | |
| TD | Louis Murphy, 74 Yd pass from Bruce Gradkowski (Sebastian Janikowski kick is good), 0:40. Drive: 3 plays, 73 yards in 0:33. | |
| 3rd Quarter | ||
| TD | Zach Miller, 27 Yd pass from Bruce Gradkowski (Sebastian Janikowski kick is good), 8:13. Drive: 9 plays, 72 yards in 4:16. | |
| FG | Shane Andrus, 38 Yd, 5:44. Drive: 7 plays, 28 yards in 2:29. | |
| FG | Sebastian Janikowski, 57 Yd, 0:34. Drive: 9 plays, 39 yards in 5:10. | |
| 4th Quarter | ||
| TD | Anthony Dixon, 1 Yd run (Joe Nedney kick is good), 1:44. Drive: 16 plays, 80 yards in 8:31. | |
| Passing | ||||
| CP/AT | YDS | TD | INT | |
| B. Gradkowski | 14/22 | 202 | 2 | 0 |
| J. Campbell | 6/8 | 93 | 0 | 0 |
| Rushing | ||||
| ATT | YDS | TD | LG | |
| M. Bush | 7 | 23 | 1 | 6 |
| M. Bennett | 2 | 12 | 0 | 12 |
| R. Cartwright | 3 | 11 | 0 | 6 |
| D. McFadden | 7 | 9 | 0 | 9 |
| Receiving | ||||
| REC | YDS | TD | LG | |
| L. Murphy | 2 | 87 | 1 | 74 |
| D. Heyward-Bey | 3 | 46 | 0 | 22 |
| M. Reece | 2 | 45 | 0 | 34 |
| Z. Miller | 1 | 27 | 1 | 27 |
| R. Cartwright | 2 | 22 | 0 | 24 |
| Y. Figurs | 2 | 18 | 0 | 10 |
| D. McFadden | 2 | 16 | 0 | 15 |
| M. Bush | 2 | 15 | 0 | 11 |
| N. Miller | 1 | 8 | 0 | 8 |
| T. Watkins | 1 | 7 | 0 | 7 |
| M. Bennett | 1 | 3 | 0 | 3 |
| B. Myers | 1 | 1 | 0 | 1 |
| Fumbles | ||||
| NO | LST | REC | YDS | |
| Y. Figurs | 1 | 0 | 0 | 0 |
| C. Morris | 0 | 0 | 1 | 0 |
| Kicking | ||||
| FG | LG | XP | PTS | |
| S. Janikowski | 1/1 | 57 | 3/3 | 6 |
| Punting | ||||
| NO | AVG | I20 | LG | |
| S. Lechler | 4 | 53.0 | 0 | 61 |
| S. Waters | 1 | 48.0 | 0 | 48 |
| Kickoff Returns | ||||
| NO | AVG | TD | LG | |
| R. Cartwright | 2 | 17.0 | 0 | 21 |
| Y. Figurs | 2 | 18.0 | 0 | 18 |
| J. Ford | 2 | 19.0 | 0 | 20 |
| Punt Returns | ||||
| NO | AVG | TD | LG | |
| Y. Figurs | 1 | 0.0 | 0 | 0 |
| J. Higgins | 2 | 6.5 | 0 | 11 |
| Defense | ||||
| T-A | SCK | INT | FF | |
| R. McClain | 6-2 | 0.0 | 0 | 0 |
| M. Huff | 5-0 | 0.0 | 0 | 0 |
| T. Branch | 4-0 | 0.0 | 0 | 0 |
| Q. Groves | 3-0 | 0.0 | 0 | 0 |
| J. Boyd | 3-1 | 0.0 | 0 | 0 |
| S. Brown | 2-1 | 0.0 | 0 | 0 |
| J. Ware | 2-1 | 0.0 | 0 | 0 |
| M. Shaughnessy | 2-0 | 0.0 | 0 | 0 |
| S. Norris | 1-0 | 0.0 | 0 | 0 |
| C. Cooper | 1-0 | 0.0 | 0 | 0 |
| T. Goethel | 1-0 | 0.0 | 0 | 0 |
| J. Porter | 1-1 | 0.0 | 0 | 0 |
| R. Brown | 1-2 | 0.0 | 0 | 0 |
| N. Asomugha | 1-0 | 0.0 | 0 | 0 |
| J. Henderson | 1-0 | 0.0 | 0 | 0 |
| T. Howard | 1-1 | 0.0 | 0 | 0 |
| W. McFadden | 1-0 | 0.0 | 0 | 0 |
| M. Mitchell | 0-1 | 0.0 | 0 | 0 |
| J. Thomas | 0-1 | 0.0 | 0 | 0 |
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