| Passing | ||||
| CP/AT | YDS | TD | INT | |
| S. Hill | 14/23 | 161 | 1 | 0 |
| Rushing | ||||
| ATT | YDS | TD | LG | |
| F. Gore | 24 | 66 | 0 | 12 |
| S. Hill | 4 | 0 | 0 | 2 |
| J. Hill | 1 | -4 | 0 | -4 |
| Receiving | ||||
| REC | YDS | TD | LG | |
| I. Bruce | 5 | 67 | 1 | 19 |
| J. Hill | 5 | 55 | 0 | 20 |
| F. Gore | 3 | 23 | 0 | 9 |
| B. Johnson | 1 | 16 | 0 | 16 |
| Fumbles | ||||
| NO | LST | REC | YDS | |
| F. Gore | 2 | 1 | 1 | 0 |
| S. Hill | 2 | 0 | 1 | -2 |
| B. Bajema | 0 | 0 | 1 | 0 |
| M. Roman | 0 | 0 | 1 | 0 |
| Kicking | ||||
| FG | LG | XP | PTS | |
| J. Nedney | 1/1 | 50 | 1/1 | 4 |
| Punting | ||||
| NO | AVG | I20 | LG | |
| A. Lee | 6 | 47.3 | 3 | 58 |
| Kickoff Returns | ||||
| NO | AVG | TD | LG | |
| D. Walker | 2 | 19.0 | 0 | 21 |
| Punt Returns | ||||
| NO | AVG | TD | LG | |
| N. Clements | 1 | 3.0 | 0 | 3 |
| Defense | ||||
| T-A | SCK | INT | FF | |
| P. Willis | 10-4 | 0.0 | 0 | 1 |
| N. Clements | 6-0 | 0.0 | 0 | 0 |
| M. Lewis | 6-0 | 0.0 | 0 | 0 |
| T. Spikes | 6-3 | 0.0 | 0 | 1 |
| R. Fields | 3-1 | 0.0 | 0 | 0 |
| P. Haralson | 3-0 | 1.0 | 0 | 0 |
| J. Smith | 3-2 | 1.5 | 0 | 0 |
| T. Banta-Cain | 2-0 | 0.0 | 0 | 0 |
| A. Franklin | 2-0 | 0.0 | 0 | 0 |
| W. Harris | 2-1 | 0.0 | 0 | 0 |
| I. Sopoaga | 2-0 | 0.0 | 0 | 0 |
| D. Strickland | 2-0 | 0.0 | 0 | 0 |
| T. Brown | 1-0 | 0.0 | 0 | 0 |
| R. Green | 1-1 | 0.5 | 0 | 0 |
| M. Hudson | 1-0 | 0.0 | 0 | 0 |
| R. McDonald | 1-1 | 0.0 | 0 | 0 |
| J. Nedney | 1-0 | 0.0 | 0 | 0 |
| M. Robinson | 1-0 | 0.0 | 0 | 0 |
| M. Roman | 1-2 | 0.0 | 0 | 0 |
| M. Lawson | 0-3 | 0.0 | 0 | 0 |
| 1 | 2 | 3 | 4 | |
| San Francisco | 7 | 3 | 0 | 0 |
| Buffalo | 0 | 0 | 3 | 0 |
| 4th Quarter | |
| 1-10-SF 47 | (3:15) F.Gore right tackle to SF 49 for 2 yards (C.Kelsay). |
| 2-8-SF 49 | (2:34) J.Hill right tackle to SF 45 for -4 yards (K.Mitchell). Reverse, handoff from S.Hill. |
| 3-12-SF 45 | (2:26) (Shotgun) S.Hill sacked at SF 34 for -11 yards (C.Kelsay). |
| 4-23-SF 34 | (2:00) A.Lee punts 51 yards to BUF 15, Center-B.Jennings. R.Parrish to BUF 19 for 4 yards (T.Banta-Cain). |
| 1-10-BUF 19 | (1:47) (Shotgun) J.Losman pass incomplete short right to M.Lynch. Through receiver's hands at BUF 21. |
| 2-10-BUF 19 | (1:42) (Shotgun) J.Losman sacked at BUF 14 for -5 yards (J.Smith). |
| 3-15-BUF 14 | (1:18) (No Huddle, Shotgun) J.Losman pass incomplete short right to J.Reed (D.Strickland). Receiver and coverage near sideline at BUF 25. |
| 4-15-BUF 14 | (1:13) (Shotgun) J.Losman pass short right to M.Lynch to BUF 15 for 1 yard (D.Strickland). Caught at BUF 14. |
| 1-10-BUF 15 | (1:04) S.Hill kneels to BUF 16 for -1 yards. |
| 2-11-BUF 16 | (:37) S.Hill kneels to BUF 17 for -1 yards. |
| Passing | ||||
| CP/AT | YDS | TD | INT | |
| T. Edwards | 10/21 | 112 | 0 | 0 |
| J. Losman | 11/17 | 93 | 0 | 0 |
| Rushing | ||||
| ATT | YDS | TD | LG | |
| M. Lynch | 16 | 134 | 0 | 50 |
| R. Parrish | 1 | 9 | 0 | 9 |
| F. Jackson | 5 | 8 | 0 | 5 |
| T. Edwards | 3 | 5 | 0 | 3 |
| Receiving | ||||
| REC | YDS | TD | LG | |
| L. Evans | 7 | 80 | 0 | 22 |
| J. Reed | 5 | 58 | 0 | 24 |
| D. Schouman | 4 | 44 | 0 | 17 |
| F. Jackson | 2 | 13 | 0 | 7 |
| R. Parrish | 2 | 9 | 0 | 6 |
| M. Lynch | 1 | 1 | 0 | 1 |
| Fumbles | ||||
| NO | LST | REC | YDS | |
| M. Lynch | 1 | 1 | 0 | 0 |
| D. Schouman | 1 | 0 | 0 | 0 |
| D. Dockery | 0 | 0 | 1 | 0 |
| B. Scott | 0 | 0 | 1 | 0 |
| Kicking | ||||
| FG | LG | XP | PTS | |
| R. Lindell | 1/3 | 22 | 0/0 | 3 |
| Punting | ||||
| NO | AVG | I20 | LG | |
| B. Moorman | 3 | 26.0 | 1 | 29 |
| Kickoff Returns | ||||
| NO | AVG | TD | LG | |
| J. Corto | 1 | 0.0 | 0 | 0 |
| F. Jackson | 1 | 18.0 | 0 | 18 |
| L. McKelvin | 1 | 37.0 | 0 | 37 |
| Punt Returns | ||||
| NO | AVG | TD | LG | |
| R. Parrish | 4 | 12.2 | 0 | 26 |
| Defense | ||||
| T-A | SCK | INT | FF | |
| C. Kelsay | 5-2 | 1.0 | 0 | 0 |
| R. Denney | 4-2 | 2.0 | 0 | 1 |
| T. McGee | 4-0 | 0.0 | 0 | 0 |
| K. Mitchell | 4-1 | 0.0 | 0 | 0 |
| R. Corner | 3-0 | 0.0 | 0 | 0 |
| M. Stroud | 3-1 | 0.0 | 0 | 0 |
| K. Williams | 3-2 | 0.0 | 0 | 1 |
| C. Ellis | 2-0 | 0.0 | 0 | 0 |
| K. Ellison | 2-0 | 0.0 | 0 | 0 |
| D. Fox | 2-0 | 0.0 | 0 | 0 |
| L. McKelvin | 2-0 | 0.0 | 0 | 0 |
| P. Posluszny | 2-2 | 0.0 | 0 | 0 |
| B. Scott | 2-1 | 0.0 | 0 | 0 |
| K. Simpson | 2-0 | 0.0 | 0 | 0 |
| S. Johnson | 1-0 | 0.0 | 0 | 0 |
| J. Wendling | 1-0 | 0.0 | 0 | 0 |
| G. Wilson | 1-0 | 0.0 | 0 | 0 |
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