| Passing | ||||
| CP/AT | YDS | TD | INT | |
| P. Rivers | 27/42 | 431 | 2 | 0 |
| Rushing | ||||
| ATT | YDS | TD | LG | |
| R. Mathews | 9 | 59 | 0 | 17 |
| P. Rivers | 1 | 14 | 0 | 14 |
| M. Tolbert | 12 | 11 | 1 | 9 |
| J. Hester | 1 | 6 | 0 | 6 |
| D. Sproles | 2 | 1 | 0 | 2 |
| L. Naanee | 1 | 0 | 0 | 0 |
| Receiving | ||||
| REC | YDS | TD | LG | |
| M. Floyd | 8 | 213 | 1 | 55 |
| A. Gates | 5 | 92 | 1 | 28 |
| D. Sproles | 3 | 32 | 0 | 23 |
| M. Tolbert | 2 | 24 | 0 | 13 |
| P. Crayton | 1 | 22 | 0 | 22 |
| K. Wilson | 2 | 17 | 0 | 16 |
| J. Hester | 2 | 16 | 0 | 11 |
| B. Davis | 2 | 11 | 0 | 6 |
| R. McMichael | 1 | 4 | 0 | 4 |
| R. Mathews | 1 | 0 | 0 | 0 |
| Fumbles | ||||
| NO | LST | REC | YDS | |
| P. Rivers | 2 | 2 | 0 | 0 |
| M. Tolbert | 1 | 1 | 0 | 0 |
| Kicking | ||||
| FG | LG | XP | PTS | |
| N. Kaeding | 2/2 | 43 | 3/3 | 9 |
| Punting | ||||
| NO | AVG | I20 | LG | |
| M. Scifres | 1 | 42.0 | 0 | 42 |
| Kickoff Returns | ||||
| NO | AVG | TD | LG | |
| D. Sproles | 4 | 23.2 | 0 | 32 |
| Punt Returns | ||||
| NO | AVG | TD | LG | |
| D. Sproles | 2 | 10.0 | 0 | 11 |
| Defense | ||||
| T-A | SCK | INT | FF | |
| P. Oliver | 6-2 | 0.0 | 0 | 0 |
| K. Burnett | 5-0 | 2.0 | 0 | 0 |
| S. Cooper | 3-0 | 1.0 | 0 | 1 |
| S. Phillips | 3-0 | 0.0 | 0 | 0 |
| K. Wilson | 3-0 | 0.0 | 0 | 0 |
| C. Thomas | 3-0 | 0.0 | 0 | 0 |
| A. Garay | 3-0 | 0.0 | 0 | 0 |
| E. Weddle | 3-1 | 0.0 | 0 | 0 |
| P. Rivers | 2-0 | 0.0 | 0 | 0 |
| T. Johnson | 2-0 | 0.0 | 0 | 0 |
| D. Strickland | 2-0 | 0.0 | 0 | 0 |
| A. Cason | 2-0 | 0.0 | 0 | 0 |
| Q. Jammer | 2-0 | 0.0 | 0 | 0 |
| S. Merriman | 1-1 | 0.0 | 0 | 0 |
| M. Scifres | 1-0 | 0.0 | 0 | 0 |
| L. Castillo | 1-1 | 0.0 | 0 | 0 |
| J. Cesaire | 1-0 | 0.0 | 0 | 0 |
| C. Obiozor | 1-0 | 0.0 | 0 | 0 |
| D. Hughes | 1-0 | 0.0 | 0 | 1 |
| Q. Teal | 1-0 | 0.0 | 0 | 0 |
| A. Applewhite | 1-0 | 0.0 | 0 | 0 |
|
|
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| 4th Quarter | |
| San Diego at 1:15 | |
| 1-20-OAK 33 | (1:15) (Shotgun) P.Rivers pass incomplete deep right to M.Floyd [M.Huff]. |
| 2-20-OAK 33 | (1:10) (Shotgun) P.Rivers sacked at OAK 36 for -3 yards (M.Huff). FUMBLES (M.Huff), RECOVERED by OAK-T.Branch at OAK 36. T.Branch for 64 yards, TOUCHDOWN. The Replay Assistant challenged the fumble ruling, and the play was Upheld. |
| S.Janikowski extra point is GOOD, Center-J.Condo, Holder-S.Lechler. | |
| S.Janikowski kicks 73 yards from OAK 30 to SD -3. D.Sproles to SD 15 for 18 yards (R.Cartwright). | |
| 1-10-SD 15 | (:53) (Shotgun) P.Rivers pass deep middle to P.Crayton to SD 37 for 22 yards (M.Huff). |
| 1-10-SD 37 | (:43) (Shotgun) P.Rivers pass incomplete short middle to C.Davis (S.Routt). |
| 2-10-SD 37 | (:37) (Shotgun) P.Rivers pass short middle to C.Davis to SD 42 for 5 yards (R.McClain). |
| 3-5-SD 42 | (:29) (Shotgun) P.Rivers pass incomplete short middle to A.Gates (M.Mitchell). |
| 4-5-SD 42 | (:27) (Shotgun) P.Rivers pass incomplete deep left to P.Crayton. |
| Oakland at :22 | |
| 1-10-SD 42 | (:22) J.Campbell kneels to SD 44 for -2 yards. |
| 1st Quarter | ||
| SAFETY | Rock Cartwright, 13:56. | |
| FG | Sebastian Janikowski, 50 Yd, 12:03. Drive: 5 plays, 18 yards in 1:53. | |
| TD | Hiram Eugene, 5 Yd blocked punt return (Sebastian Janikowski kick is good), 10:33. | |
| 2nd Quarter | ||
| TD | Antonio Gates, 19 Yd pass from Philip Rivers (Nate Kaeding kick is good), 10:07. Drive: 8 plays, 77 yards in 4:01. | |
| TD | Mike Tolbert, 4 Yd run (Nate Kaeding kick is good), 4:49. Drive: 8 plays, 81 yards in 4:08. | |
| FG | Sebastian Janikowski, 30 Yd, 0:58. Drive: 12 plays, 55 yards in 3:51. | |
| FG | Nate Kaeding, 43 Yd, 0:01. Drive: 6 plays, 45 yards in 0:57. | |
| 3rd Quarter | ||
| TD | Malcom Floyd, 41 Yd pass from Philip Rivers (Nate Kaeding kick is good), 7:38. Drive: 2 plays, 63 yards in 0:42. | |
| TD | Zach Miller, 1 Yd pass from Jason Campbell (Sebastian Janikowski kick is good), 1:12. Drive: 12 plays, 97 yards in 6:26. | |
| 4th Quarter | ||
| FG | Nate Kaeding, 34 Yd, 12:00. Drive: 9 plays, 63 yards in 4:12. | |
| TD | Michael Bush, 3 Yd run (Jason Campbell 2 Pt. Conversion pass to Johnnie Lee Higgins failed), 3:39. Drive: 14 plays, 73 yards in 8:21. | |
| TD | Tyvon Branch, 64 Yd fumble return (Sebastian Janikowski kick is good), 0:58. | |
| Passing | ||||
| CP/AT | YDS | TD | INT | |
| J. Campbell | 13/18 | 159 | 1 | 0 |
| B. Gradkowski | 1/7 | 14 | 0 | 0 |
| Rushing | ||||
| ATT | YDS | TD | LG | |
| M. Bush | 26 | 104 | 1 | 14 |
| J. Campbell | 4 | 7 | 0 | 6 |
| Receiving | ||||
| REC | YDS | TD | LG | |
| Z. Miller | 6 | 62 | 1 | 18 |
| L. Murphy | 2 | 61 | 0 | 58 |
| M. Bush | 3 | 31 | 0 | 16 |
| B. Myers | 1 | 12 | 0 | 12 |
| M. Reece | 2 | 7 | 0 | 4 |
| Fumbles | ||||
| NO | LST | REC | YDS | |
| J. Campbell | 1 | 0 | 0 | 0 |
| J. Ford | 1 | 0 | 1 | 0 |
| Z. Miller | 1 | 0 | 0 | 0 |
| T. Branch | 0 | 0 | 1 | 64 |
| M. Mitchell | 0 | 0 | 1 | 12 |
| R. Brown | 0 | 0 | 1 | 0 |
| D. Loper | 0 | 0 | 1 | 3 |
| L. Houston | 0 | 0 | 1 | 0 |
| Kicking | ||||
| FG | LG | XP | PTS | |
| S. Janikowski | 2/2 | 50 | 3/3 | 9 |
| Punting | ||||
| NO | AVG | I20 | LG | |
| S. Lechler | 4 | 52.8 | 1 | 63 |
| Kickoff Returns | ||||
| NO | AVG | TD | LG | |
| H. Eugene | 1 | 0.0 | 0 | 0 |
| J. Ford | 5 | 18.2 | 0 | 25 |
| Punt Returns | ||||
| NO | AVG | TD | LG | |
| N. Miller | 1 | 46.0 | 0 | 46 |
| Defense | ||||
| T-A | SCK | INT | FF | |
| M. Huff | 9-2 | 1.0 | 0 | 1 |
| K. Wimbley | 5-3 | 0.0 | 0 | 0 |
| T. Scott | 5-2 | 0.0 | 0 | 0 |
| R. McClain | 5-2 | 0.0 | 0 | 0 |
| M. Mitchell | 3-1 | 0.0 | 0 | 0 |
| T. Kelly | 3-1 | 1.0 | 0 | 0 |
| N. Asomugha | 3-1 | 0.0 | 0 | 0 |
| M. Shaughnessy | 3-3 | 1.0 | 0 | 1 |
| R. Seymour | 3-1 | 0.0 | 0 | 0 |
| R. Cartwright | 2-0 | 0.0 | 0 | 0 |
| T. Branch | 2-1 | 0.0 | 0 | 0 |
| S. Routt | 2-1 | 0.0 | 0 | 0 |
| S. Brown | 1-0 | 0.0 | 0 | 0 |
| R. Brown | 1-0 | 0.0 | 0 | 1 |
| C. Johnson | 1-0 | 0.0 | 0 | 0 |
| H. Eugene | 1-0 | 0.0 | 0 | 0 |
| L. Houston | 1-0 | 0.0 | 0 | 0 |
| S. Williams | 1-0 | 0.0 | 0 | 0 |
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