| Passing | ||||
| CP/AT | YDS | TD | INT | |
| P. Rivers | 22/37 | 249 | 1 | 1 |
| Rushing | ||||
| ATT | YDS | TD | LG | |
| R. Mathews | 12 | 64 | 0 | 19 |
| D. Sproles | 1 | 9 | 0 | 9 |
| J. Hester | 1 | 3 | 0 | 3 |
| M. Tolbert | 3 | 3 | 1 | 1 |
| Receiving | ||||
| REC | YDS | TD | LG | |
| P. Crayton | 6 | 117 | 0 | 29 |
| D. Sproles | 5 | 48 | 0 | 11 |
| B. Davis | 3 | 39 | 1 | 17 |
| M. Floyd | 2 | 15 | 0 | 12 |
| R. Mathews | 3 | 12 | 0 | 11 |
| A. Gates | 2 | 12 | 0 | 9 |
| J. Hester | 1 | 6 | 0 | 6 |
| Fumbles | ||||
| NO | LST | REC | YDS | |
| Kicking | ||||
| FG | LG | XP | PTS | |
| N. Kaeding | 1/2 | 41 | 2/2 | 5 |
| Punting | ||||
| NO | AVG | I20 | LG | |
| M. Scifres | 6 | 59.5 | 0 | 64 |
| Kickoff Returns | ||||
| NO | AVG | TD | LG | |
| D. Sproles | 5 | 23.0 | 0 | 31 |
| Punt Returns | ||||
| NO | AVG | TD | LG | |
| D. Sproles | 2 | 6.5 | 0 | 9 |
| Defense | ||||
| T-A | SCK | INT | FF | |
| E. Weddle | 11-1 | 0.0 | 0 | 0 |
| S. Cooper | 6-0 | 0.0 | 0 | 0 |
| P. Oliver | 6-0 | 0.0 | 0 | 0 |
| A. Garay | 5-1 | 1.0 | 0 | 0 |
| A. Cason | 4-0 | 0.0 | 0 | 0 |
| D. Strickland | 3-0 | 0.0 | 0 | 0 |
| L. Castillo | 2-1 | 0.5 | 0 | 0 |
| T. Johnson | 2-1 | 0.0 | 0 | 0 |
| K. Burnett | 2-1 | 1.0 | 0 | 0 |
| C. Thomas | 2-0 | 0.0 | 0 | 0 |
| A. Applewhite | 2-1 | 0.0 | 0 | 0 |
| J. Hester | 1-0 | 0.0 | 0 | 0 |
| R. McMichael | 1-0 | 0.0 | 0 | 0 |
| S. Phillips | 1-1 | 0.0 | 0 | 0 |
| M. Tolbert | 1-0 | 0.0 | 0 | 0 |
| J. Cesaire | 1-1 | 0.5 | 0 | 0 |
| T. Carter | 1-0 | 0.0 | 0 | 0 |
| Q. Jammer | 1-0 | 0.0 | 0 | 0 |
| K. Wilson | 0-1 | 0.0 | 0 | 0 |
|
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| 4th Quarter | |
| N.Kaeding extra point is GOOD, Center-M.Windt, Holder-M.Scifres. | |
| M.Scifres kicks 62 yards from SD 30 to SL 8. D.Amendola to SL 32 for 24 yards (R.Goodman). | |
| St. Louis at 3:11 | |
| 1-10-STL 32 | (3:11) S.Jackson left tackle to SL 33 for 1 yard (P.Oliver). |
| 2-9-STL 33 | (2:36) S.Jackson left guard to SL 36 for 3 yards (L.Castillo). |
| 3-6-STL 36 | (2:24) S.Jackson left guard to SL 45 for 9 yards (A.Applewhite). |
| 1-10-STL 45 | (2:00) S.Jackson right end to SL 48 for 3 yards (D.Strickland). |
| 2-7-STL 48 | (1:54) S.Jackson right tackle to SD 40 for 12 yards (E.Weddle). |
| 1-10-SD 40 | (1:47) S.Bradford kneels to SD 41 for -1 yards. |
| 2-11-SD 41 | (1:07) S.Bradford kneels to SD 42 for -1 yards. |
| 3-12-SD 42 | (:33) S.Bradford kneels to SD 43 for -1 yards. |
| 1st Quarter | ||
| FG | Josh Brown, 39 Yd, 9:31. Drive: 8 plays, 30 yards in 2:39. | |
| TD | Danario Alexander, 38 Yd pass from Sam Bradford (Josh Brown kick is good), 0:43. Drive: 5 plays, 80 yards in 2:31. | |
| 2nd Quarter | ||
| TD | Steven Jackson, 7 Yd run (Josh Brown kick is good), 1:39. Drive: 17 plays, 67 yards in 7:58. | |
| FG | Nate Kaeding, 41 Yd, 0:23. Drive: 8 plays, 53 yards in 1:16. | |
| 3rd Quarter | ||
| TD | Mike Tolbert, 1 Yd run (Nate Kaeding kick is good), 4:41. Drive: 11 plays, 68 yards in 5:48. | |
| 4th Quarter | ||
| FG | Josh Brown, 48 Yd, 3:56. Drive: 8 plays, 32 yards in 4:15. | |
| TD | Buster Davis, 5 Yd pass from Philip Rivers (Nate Kaeding kick is good), 3:16. Drive: 5 plays, 76 yards in 0:40. | |
| Passing | ||||
| CP/AT | YDS | TD | INT | |
| S. Bradford | 18/31 | 198 | 1 | 0 |
| Rushing | ||||
| ATT | YDS | TD | LG | |
| S. Jackson | 29 | 109 | 1 | 13 |
| S. Bradford | 6 | 8 | 0 | 11 |
| Receiving | ||||
| REC | YDS | TD | LG | |
| B. Bajema | 3 | 34 | 0 | 18 |
| B. Gibson | 3 | 33 | 0 | 12 |
| M. Gilyard | 1 | 21 | 0 | 21 |
| D. Amendola | 3 | 19 | 0 | 11 |
| D. Fells | 1 | 8 | 0 | 8 |
| M. Hoomanawanui | 1 | 5 | 0 | 5 |
| M. Karney | 1 | 4 | 0 | 4 |
| S. Jackson | 1 | 2 | 0 | 2 |
| Fumbles | ||||
| NO | LST | REC | YDS | |
| Kicking | ||||
| FG | LG | XP | PTS | |
| J. Brown | 2/2 | 48 | 2/2 | 8 |
| Punting | ||||
| NO | AVG | I20 | LG | |
| D. Jones | 6 | 41.2 | 1 | 48 |
| Kickoff Returns | ||||
| NO | AVG | TD | LG | |
| D. Amendola | 2 | 23.0 | 0 | 24 |
| M. Gilyard | 1 | 23.0 | 0 | 23 |
| Punt Returns | ||||
| NO | AVG | TD | LG | |
| D. Amendola | 4 | 18.0 | 0 | 42 |
| Defense | ||||
| T-A | SCK | INT | FF | |
| B. Fletcher | 8-0 | 0.0 | 0 | 0 |
| O. Atogwe | 5-0 | 0.0 | 1 | 0 |
| R. Bartell | 5-1 | 0.0 | 0 | 0 |
| J. Laurinaitis | 5-0 | 0.0 | 0 | 0 |
| L. Grant | 4-1 | 2.0 | 0 | 0 |
| J. Butler | 4-0 | 0.0 | 0 | 0 |
| J. Hall | 3-0 | 2.0 | 0 | 0 |
| C. Long | 2-0 | 2.0 | 0 | 0 |
| N. Diggs | 2-0 | 0.0 | 0 | 0 |
| C. Dahl | 2-0 | 0.0 | 0 | 0 |
| G. Gibson | 2-0 | 0.0 | 0 | 0 |
| J. Murphy | 2-0 | 0.0 | 0 | 0 |
| D. Fells | 1-0 | 0.0 | 0 | 0 |
| K. Darby | 1-0 | 0.0 | 0 | 0 |
| K. Toston | 1-0 | 0.0 | 0 | 0 |
| C. Ah You | 1-1 | 0.0 | 0 | 0 |
| F. Robbins | 1-1 | 1.0 | 0 | 0 |
| B. Kehl | 1-0 | 0.0 | 0 | 0 |
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