| Passing | ||||
| CP/AT | YDS | TD | INT | |
| J. Freeman | 17/33 | 187 | 0 | 2 |
| J. Johnson | 1/2 | 7 | 0 | 0 |
| Rushing | ||||
| ATT | YDS | TD | LG | |
| L. Blount | 10 | 34 | 0 | 9 |
| E. Graham | 5 | 30 | 0 | 8 |
| A. Bradford | 5 | 13 | 0 | 4 |
| K. Lumpkin | 2 | 7 | 0 | 5 |
| J. Freeman | 1 | 2 | 0 | 2 |
| Receiving | ||||
| REC | YDS | TD | LG | |
| K. Winslow | 5 | 54 | 0 | 17 |
| A. Benn | 3 | 46 | 0 | 33 |
| L. Blount | 2 | 31 | 0 | 29 |
| M. Williams | 4 | 28 | 0 | 13 |
| D. Briscoe | 2 | 18 | 0 | 11 |
| P. Parker | 1 | 13 | 0 | 13 |
| K. Lumpkin | 1 | 4 | 0 | 4 |
| Fumbles | ||||
| NO | LST | REC | YDS | |
| M. Williams | 1 | 1 | 0 | 0 |
| M. Foster | 0 | 0 | 1 | 0 |
| Kicking | ||||
| FG | LG | XP | PTS | |
| C. Barth | 1/1 | 24 | 0/0 | 3 |
| Punting | ||||
| NO | AVG | I20 | LG | |
| M. Koenen | 6 | 43.2 | 3 | 58 |
| Kickoff Returns | ||||
| NO | AVG | TD | LG | |
| P. Parker | 4 | 21.5 | 0 | 39 |
| Punt Returns | ||||
| NO | AVG | TD | LG | |
| Defense | ||||
| T-A | SCK | INT | FF | |
| S. Jones | 9-0 | 0.0 | 0 | 0 |
| C. Lynch | 6-0 | 0.0 | 0 | 0 |
| D. Watson | 5-2 | 0.0 | 0 | 0 |
| G. Hayes | 4-1 | 0.0 | 0 | 0 |
| M. Bennett | 4-0 | 0.0 | 0 | 0 |
| D. Bowers | 2-0 | 0.0 | 0 | 0 |
| F. Okam | 2-0 | 0.0 | 0 | 0 |
| M. Foster | 2-1 | 0.0 | 0 | 0 |
| M. Lewis | 2-0 | 0.0 | 0 | 0 |
| A. Hayward | 2-0 | 0.0 | 0 | 0 |
| L. Asante | 1-0 | 0.0 | 0 | 0 |
| T. Crowder | 1-1 | 0.0 | 0 | 0 |
| M. Williams | 1-0 | 0.0 | 0 | 0 |
| A. Gaitor | 1-0 | 0.0 | 0 | 0 |
| E. Biggers | 1-0 | 0.0 | 0 | 0 |
| A. Clayborn | 1-1 | 0.0 | 0 | 0 |
| R. Barber | 1-0 | 0.0 | 0 | 0 |
| E. Graham | 1-0 | 0.0 | 0 | 0 |
| E. Lorig | 1-0 | 0.0 | 0 | 0 |
| E. Mack | 1-0 | 0.0 | 0 | 0 |
| D. Penn | 0-1 | 0.0 | 0 | 0 |
|
|
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| 4th Quarter | |
| D.Akers kicks 63 yards from SF 35 to TB 2. P.Parker to TB 41 for 39 yards (D.Akers, B.Costanzo). | |
| Tampa Bay at 3:38 | |
| 1-10-TB 41 | (3:38) J. Johnson in at QB A.Bradford left end to TB 45 for 4 yards (L.Grant). |
| 2-6-TB 45 | (3:00) A.Bradford left tackle to TB 48 for 3 yards (D.Dobbs). |
| 3-3-TB 48 | (2:20) (Shotgun) J.Johnson pass short left to D.Briscoe pushed ob at SF 45 for 7 yards (C.Spillman). Caught at SF 45. 0-yds YAC. |
| 1-10-SF 45 | (2:16) D.Dotson reported in as eligible. A.Bradford left tackle to SF 43 for 2 yards (D.Whitner, R.Jean Francois). |
| 2-8-SF 43 | (2:00) J.Johnson pass incomplete short left to M.Spurlock (T.Brown). |
| 3-8-SF 43 | (1:56) (Shotgun) J.Johnson sacked at SF 45 for -2 yards (Ald.Smith). |
| 4-10-SF 45 | (1:16) M.Koenen punts 30 yards to SF 15, Center-C.Yount, fair catch by T.Ginn. PENALTY on TB-M.Lewis, Fair Catch Interference, 15 yards, enforced at SF 15. |
| San Francisco at 1:07 | |
| 1-10-SF 30 | (1:07) C.Kaepernick kneels to SF 29 for -1 yards. |
| 2-11-SF 29 | (:39) C.Kaepernick kneels to SF 28 for -1 yards. |
| 1st Quarter | ||
| TD | Delanie Walker, 26 Yd pass from Alex Smith (David Akers kick is good), 10:26. Drive: 4 plays, 50 yards in 2:28. | |
| FG | Connor Barth, 24 Yd, 3:58. Drive: 13 plays, 74 yards in 6:28. | |
| 2nd Quarter | ||
| TD | Carlos Rogers, 31 Yd interception return (David Akers kick is good), 14:46. | |
| TD | Frank Gore, 2 Yd run (David Akers kick is good), 7:56. Drive: 5 plays, 57 yards in 2:35. | |
| FG | David Akers, 37 Yd, 4:29. Drive: 6 plays, 32 yards in 2:23. | |
| 3rd Quarter | ||
| TD | Vernon Davis, 23 Yd pass from Alex Smith (David Akers kick is good), 9:43. Drive: 7 plays, 80 yards in 5:17. | |
| FG | David Akers, 27 Yd, 2:36. Drive: 10 plays, 57 yards in 4:26. | |
| 4th Quarter | ||
| TD | Vernon Davis, 14 Yd pass from Alex Smith (David Akers kick is good), 14:52. Drive: 4 plays, 36 yards in 1:15. | |
| TD | Anthony Dixon, 1 Yd run (David Akers kick is good), 3:48. Drive: 11 plays, 90 yards in 6:09. | |
| Passing | ||||
| CP/AT | YDS | TD | INT | |
| A. Smith | 11/19 | 170 | 3 | 0 |
| C. Kaepernick | 3/3 | 35 | 0 | 0 |
| Rushing | ||||
| ATT | YDS | TD | LG | |
| F. Gore | 20 | 125 | 1 | 21 |
| K. Hunter | 9 | 65 | 0 | 44 |
| T. Ginn | 1 | 24 | 0 | 24 |
| A. Dixon | 2 | 4 | 1 | 3 |
| B. Miller | 1 | 0 | 0 | 0 |
| C. Kaepernick | 2 | -2 | 0 | -1 |
| V. Davis | 1 | -3 | 0 | -3 |
| Receiving | ||||
| REC | YDS | TD | LG | |
| J. Morgan | 5 | 75 | 0 | 24 |
| V. Davis | 3 | 39 | 2 | 23 |
| D. Walker | 2 | 37 | 1 | 26 |
| M. Crabtree | 2 | 36 | 0 | 21 |
| F. Gore | 2 | 18 | 0 | 12 |
| Fumbles | ||||
| NO | LST | REC | YDS | |
| F. Gore | 1 | 1 | 0 | 0 |
| P. Willis | 0 | 0 | 1 | 0 |
| Kicking | ||||
| FG | LG | XP | PTS | |
| D. Akers | 2/2 | 37 | 6/6 | 12 |
| Punting | ||||
| NO | AVG | I20 | LG | |
| A. Lee | 1 | 38.0 | 1 | 38 |
| Kickoff Returns | ||||
| NO | AVG | TD | LG | |
| K. Hunter | 1 | 22.0 | 0 | 22 |
| Punt Returns | ||||
| NO | AVG | TD | LG | |
| T. Ginn | 3 | 17.0 | 0 | 29 |
| Defense | ||||
| T-A | SCK | INT | FF | |
| P. Willis | 10-2 | 0.0 | 0 | 0 |
| N. Bowman | 5-1 | 0.0 | 0 | 0 |
| P. Haralson | 4-0 | 0.0 | 0 | 0 |
| D. Whitner | 4-0 | 0.0 | 0 | 0 |
| J. Smith | 4-0 | 1.0 | 0 | 0 |
| D. Goldson | 4-0 | 0.0 | 0 | 1 |
| R. Smith | 3-0 | 0.0 | 0 | 0 |
| R. Jean Francois | 2-1 | 0.0 | 0 | 0 |
| A. Smith | 2-0 | 2.0 | 0 | 0 |
| C. Culliver | 1-0 | 0.0 | 1 | 0 |
| C. Rogers | 1-0 | 0.0 | 1 | 0 |
| T. Brown | 1-0 | 0.0 | 0 | 0 |
| C. Spillman | 1-0 | 0.0 | 0 | 0 |
| F. Gore | 1-0 | 0.0 | 0 | 0 |
| B. Costanzo | 1-1 | 0.0 | 0 | 0 |
| L. Grant | 1-0 | 0.0 | 0 | 0 |
| A. Brooks | 1-0 | 0.0 | 0 | 0 |
| D. Akers | 1-0 | 0.0 | 0 | 0 |
| D. Dobbs | 1-0 | 0.0 | 0 | 0 |
| C. Jones | 1-0 | 0.0 | 0 | 0 |
| R. McDonald | 0-1 | 0.0 | 0 | 0 |
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