| Passing | ||||
| CP/AT | YDS | TD | INT | |
| P. Rivers | 16/32 | 179 | 1 | 2 |
| Rushing | ||||
| ATT | YDS | TD | LG | |
| M. Tolbert | 11 | 58 | 1 | 29 |
| R. Mathews | 13 | 39 | 0 | 9 |
| P. Rivers | 1 | -1 | 0 | -1 |
| Receiving | ||||
| REC | YDS | TD | LG | |
| A. Gates | 5 | 54 | 1 | 18 |
| R. McMichael | 3 | 45 | 0 | 30 |
| M. Floyd | 2 | 36 | 0 | 28 |
| R. Mathews | 4 | 26 | 0 | 9 |
| V. Jackson | 1 | 15 | 0 | 15 |
| P. Crayton | 1 | 3 | 0 | 3 |
| Fumbles | ||||
| NO | LST | REC | YDS | |
| D. Butler | 0 | 0 | 1 | 37 |
| Kicking | ||||
| FG | LG | XP | PTS | |
| N. Novak | 0/0 | 0 | 3/3 | 3 |
| Punting | ||||
| NO | AVG | I20 | LG | |
| M. Scifres | 4 | 50.2 | 1 | 58 |
| Kickoff Returns | ||||
| NO | AVG | TD | LG | |
| R. Goodman | 6 | 23.2 | 0 | 31 |
| Punt Returns | ||||
| NO | AVG | TD | LG | |
| P. Crayton | 1 | 0.0 | 0 | 0 |
| Defense | ||||
| T-A | SCK | INT | FF | |
| S. Gregory | 6-1 | 0.0 | 0 | 0 |
| D. Butler | 6-3 | 0.0 | 0 | 1 |
| E. Weddle | 5-1 | 0.0 | 1 | 0 |
| T. Spikes | 4-3 | 0.0 | 0 | 0 |
| S. Phillips | 4-2 | 2.0 | 0 | 0 |
| A. Garay | 4-2 | 0.0 | 0 | 0 |
| Q. Jammer | 4-1 | 0.0 | 0 | 0 |
| N. Diggs | 3-0 | 0.0 | 0 | 0 |
| A. Gachkar | 2-1 | 0.0 | 0 | 0 |
| C. Liuget | 1-0 | 0.0 | 0 | 0 |
| R. McMichael | 1-1 | 0.0 | 0 | 0 |
| T. LaBoy | 1-1 | 0.0 | 0 | 0 |
| T. Harris | 1-0 | 0.0 | 0 | 0 |
| D. Hughes | 1-0 | 0.0 | 0 | 0 |
| A. Cason | 1-0 | 0.0 | 0 | 0 |
| V. Jackson | 1-0 | 0.0 | 0 | 0 |
| V. Martin | 0-2 | 0.0 | 0 | 0 |
|
|
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| 4th Quarter | |
| New York at 1:51 | |
| 2-3-SD 3 | (1:51) S.Greene right tackle to SD 3 for no gain (N.Diggs). |
| 3-3-SD 3 | (1:48) M.Sanchez sacked at SD 12 for -9 yards (S.Phillips). |
| 4-12-SD 12 | (1:40) N.Folk 30 yard field goal is GOOD, Center-T.Purdum, Holder-M.Brunell. |
| N.Folk kicks 66 yards from NYJ 35 to SD -1. R.Goodman to SD 24 for 25 yards (E.Lankster). | |
| San Diego at 1:29 | |
| 1-10-SD 24 | (1:29) (Shotgun) P.Rivers pass short middle to A.Gates to SD 42 for 18 yards (D.Strickland). |
| 1-10-SD 42 | (:59) (No Huddle, Shotgun) P.Rivers pass short left to P.Crayton to SD 45 for 3 yards (K.Wilson). |
| 2-7-SD 45 | (:37) (No Huddle, Shotgun) P.Rivers pass short left to R.Mathews to SD 49 for 4 yards (E.Smith) [A.Maybin]. |
| 3-3-SD 49 | (:37) (No Huddle, Shotgun) P.Rivers pass incomplete deep right to V.Brown. |
| 4-3-SD 49 | (:11) (Shotgun) P.Rivers pass incomplete short right to A.Gates. |
| New York at :03 | |
| 1-10-SD 49 | (:03) M.Sanchez kneels to 50 for -1 yards. |
| 1st Quarter | ||
| TD | Donald Butler, 37 Yd fumble return (Nick Novak kick is good), 13:11. | |
| FG | Nick Folk, 35 Yd, 8:25. Drive: 8 plays, 64 yards in 4:46. | |
| 2nd Quarter | ||
| TD | Antonio Gates, 2 Yd pass from Philip Rivers (Nick Novak kick is good), 12:11. Drive: 14 plays, 76 yards in 6:28. | |
| TD | Plaxico Burress, 3 Yd pass from Mark Sanchez (Nick Folk kick is good), 7:18. Drive: 8 plays, 77 yards in 4:53. | |
| TD | Mike Tolbert, 1 Yd run (Nick Novak kick is good), 1:16. Drive: 11 plays, 87 yards in 6:02. | |
| 3rd Quarter | ||
| TD | Plaxico Burress, 4 Yd pass from Mark Sanchez (Nick Folk kick is good), 2:57. Drive: 10 plays, 55 yards in 4:33. | |
| 4th Quarter | ||
| TD | Plaxico Burress, 3 Yd pass from Mark Sanchez (Nick Folk kick is good), 8:41. Drive: 5 plays, 19 yards in 2:15. | |
| FG | Nick Folk, 30 Yd, 1:36. Drive: 9 plays, 35 yards in 3:47. | |
| Passing | ||||
| CP/AT | YDS | TD | INT | |
| M. Sanchez | 18/33 | 173 | 3 | 1 |
| Rushing | ||||
| ATT | YDS | TD | LG | |
| S. Greene | 20 | 112 | 0 | 24 |
| M. Sanchez | 3 | 25 | 0 | 25 |
| L. Tomlinson | 5 | 14 | 0 | 9 |
| J. McKnight | 3 | 11 | 0 | 4 |
| Receiving | ||||
| REC | YDS | TD | LG | |
| D. Keller | 4 | 53 | 0 | 34 |
| L. Tomlinson | 3 | 37 | 0 | 19 |
| J. Kerley | 4 | 29 | 0 | 10 |
| P. Burress | 4 | 25 | 3 | 15 |
| S. Holmes | 2 | 24 | 0 | 16 |
| S. Greene | 1 | 5 | 0 | 5 |
| Fumbles | ||||
| NO | LST | REC | YDS | |
| D. Keller | 1 | 1 | 0 | 0 |
| Kicking | ||||
| FG | LG | XP | PTS | |
| N. Folk | 2/2 | 35 | 3/3 | 9 |
| Punting | ||||
| NO | AVG | I20 | LG | |
| T. Conley | 3 | 36.7 | 1 | 42 |
| Kickoff Returns | ||||
| NO | AVG | TD | LG | |
| J. McKnight | 3 | 26.3 | 0 | 34 |
| Punt Returns | ||||
| NO | AVG | TD | LG | |
| J. Kerley | 1 | 7.0 | 0 | 7 |
| J. McKnight | 1 | 7.0 | 0 | 7 |
| Defense | ||||
| T-A | SCK | INT | FF | |
| E. Smith | 8-2 | 0.0 | 0 | 0 |
| A. Cromartie | 4-0 | 0.0 | 0 | 0 |
| M. Wilkerson | 3-2 | 0.0 | 0 | 0 |
| J. Leonhard | 2-1 | 0.0 | 0 | 0 |
| D. Harris | 2-1 | 0.0 | 0 | 0 |
| B. Pool | 2-1 | 0.0 | 0 | 0 |
| B. Scott | 2-1 | 0.0 | 0 | 0 |
| D. Strickland | 2-0 | 0.0 | 0 | 0 |
| C. Pace | 2-0 | 0.0 | 0 | 0 |
| K. Wilson | 2-0 | 0.0 | 1 | 0 |
| E. Lankster | 2-0 | 0.0 | 0 | 0 |
| R. Pitoitua | 1-0 | 0.0 | 0 | 0 |
| D. Revis | 1-1 | 0.0 | 1 | 0 |
| A. Maybin | 1-1 | 1.0 | 0 | 0 |
| M. Cole | 1-1 | 0.0 | 0 | 0 |
| D. Ferguson | 1-0 | 0.0 | 0 | 0 |
| M. Dixon | 1-0 | 0.0 | 0 | 0 |
| E. Cook | 1-0 | 0.0 | 0 | 0 |
| K. Ellis | 0-1 | 0.0 | 0 | 0 |
| J. Mauga | 0-2 | 0.0 | 0 | 0 |
| S. Pouha | 0-2 | 0.0 | 0 | 0 |
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