| Passing | ||||
| CP/AT | YDS | TD | INT | |
| J. Skelton | 6/19 | 99 | 0 | 3 |
| R. Bartel | 8/16 | 64 | 1 | 0 |
| Rushing | ||||
| ATT | YDS | TD | LG | |
| C. Taylor | 1 | 34 | 0 | 34 |
| B. Wells | 8 | 33 | 0 | 9 |
| R. Bartel | 1 | 9 | 0 | 9 |
| L. Stephens-Howling | 1 | 4 | 0 | 4 |
| J. Skelton | 1 | 0 | 0 | 0 |
| Receiving | ||||
| REC | YDS | TD | LG | |
| A. Roberts | 3 | 51 | 0 | 45 |
| E. Doucet | 6 | 50 | 0 | 16 |
| L. Fitzgerald | 3 | 41 | 1 | 23 |
| R. Maui'a | 1 | 12 | 0 | 12 |
| D. Sampson | 1 | 9 | 0 | 9 |
| Fumbles | ||||
| NO | LST | REC | YDS | |
| J. Skelton | 1 | 0 | 1 | 0 |
| B. Wells | 1 | 1 | 0 | 0 |
| P. Peterson | 1 | 1 | 0 | 0 |
| Kicking | ||||
| FG | LG | XP | PTS | |
| J. Feely | 0/0 | 0 | 1/1 | 1 |
| Punting | ||||
| NO | AVG | I20 | LG | |
| D. Zastudil | 6 | 46.5 | 1 | 51 |
| Kickoff Returns | ||||
| NO | AVG | TD | LG | |
| L. Stephens-Howling | 3 | 24.7 | 0 | 27 |
| Punt Returns | ||||
| NO | AVG | TD | LG | |
| P. Peterson | 2 | 11.0 | 0 | 12 |
| Defense | ||||
| T-A | SCK | INT | FF | |
| P. Lenon | 9-0 | 0.0 | 0 | 0 |
| R. Johnson | 7-1 | 0.0 | 0 | 0 |
| D. Williams | 6-0 | 0.0 | 0 | 0 |
| D. Washington | 5-0 | 0.0 | 1 | 0 |
| O. Schofield | 5-0 | 0.0 | 0 | 0 |
| P. Peterson | 4-0 | 0.0 | 0 | 0 |
| S. Bradley | 4-0 | 0.0 | 0 | 0 |
| M. Adams | 4-0 | 0.0 | 0 | 0 |
| A. Wilson | 4-0 | 0.0 | 0 | 0 |
| C. Campbell | 4-0 | 0.0 | 0 | 0 |
| S. Acho | 3-2 | 0.0 | 0 | 0 |
| C. Haggans | 3-0 | 0.0 | 0 | 0 |
| R. Marshall | 3-0 | 0.0 | 0 | 0 |
| V. Holliday | 2-0 | 0.0 | 0 | 0 |
| L. Stephens-Howling | 1-0 | 0.0 | 0 | 0 |
| L. Fitzgerald | 1-0 | 0.0 | 0 | 0 |
| A. Jefferson | 1-0 | 0.0 | 0 | 0 |
| A. Roberts | 1-0 | 0.0 | 0 | 0 |
| B. Wells | 1-0 | 0.0 | 0 | 0 |
| H. Abdullah | 1-0 | 0.0 | 0 | 0 |
| L. Brown | 1-0 | 0.0 | 0 | 0 |
| D. Dockett | 1-0 | 0.0 | 0 | 0 |
| D. Carter | 1-0 | 0.0 | 0 | 0 |
| N. Eason | 0-1 | 0.0 | 0 | 0 |
| S. Considine | 0-1 | 0.0 | 0 | 0 |
| R. Bartel | 0-1 | 0.0 | 0 | 0 |
|
|
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| 4th Quarter | |
| Arizona at 3:41 | |
| 3-10-SF 16 | (3:41) (Shotgun) R.Bartel pass incomplete deep middle to E.Doucet. |
| 4-10-SF 16 | (3:36) (Shotgun) R.Bartel pass short middle to E.Doucet to SF 10 for 6 yards (N.Bowman) [J.Smith]. Caught at SF 10. 0-yd YAC |
| San Francisco at 3:27 | |
| 1-10-SF 10 | (3:27) A.Dixon left tackle to SF 12 for 2 yards (S.Bradley). |
| 2-8-SF 12 | (3:20) A.Dixon right guard to SF 21 for 9 yards (R.Marshall). |
| 1-10-SF 21 | (2:37) A.Dixon right tackle to SF 27 for 6 yards (R.Johnson). |
| 2-4-SF 27 | (2:30) A.Dixon right tackle to SF 29 for 2 yards (R.Marshall). |
| 3-2-SF 29 | (2:00) A.Dixon left tackle to SF 37 for 8 yards (D.Washington). PENALTY on ARZ-D.Washington, Face Mask (15 Yards), 15 yards, enforced at SF 37. |
| 1-10-ARI 48 | (1:50) Alex Smith kneels to ARZ 48 for no gain. |
| 2-10-ARI 48 | (1:14) Alex Smith kneels to ARZ 48 for no gain. |
| 3-10-ARI 48 | (:42) Alex Smith kneels to ARZ 49 for -1 yards. |
| 1st Quarter | ||
| FG | David Akers, 22 Yd, 3:10. Drive: 9 plays, 59 yards in 3:48. | |
| FG | David Akers, 43 Yd, 2:06. Drive: 4 plays, 1 yards in 0:59. | |
| 2nd Quarter | ||
| FG | David Akers, 29 Yd, 0:56. Drive: 13 plays, 75 yards in 6:06. | |
| 3rd Quarter | ||
| TD | Kyle Williams, 8 Yd pass from Alex Smith (David Akers kick is good), 7:12. Drive: 13 plays, 84 yards in 7:48. | |
| TD | Vernon Davis, 18 Yd pass from Alex Smith (David Akers kick is good), 4:14. Drive: 4 plays, 37 yards in 1:53. | |
| 4th Quarter | ||
| TD | Larry Fitzgerald, 23 Yd pass from Richard Bartel (Jay Feely kick is good), 8:38. Drive: 6 plays, 84 yards in 2:36. | |
| Passing | ||||
| CP/AT | YDS | TD | INT | |
| A. Smith | 20/38 | 267 | 2 | 1 |
| Rushing | ||||
| ATT | YDS | TD | LG | |
| F. Gore | 24 | 88 | 0 | 14 |
| A. Dixon | 7 | 32 | 0 | 9 |
| K. Hunter | 11 | 27 | 0 | 9 |
| A. Smith | 7 | 17 | 0 | 11 |
| Receiving | ||||
| REC | YDS | TD | LG | |
| M. Crabtree | 7 | 120 | 0 | 38 |
| V. Davis | 5 | 67 | 1 | 27 |
| K. Williams | 5 | 54 | 1 | 13 |
| K. Hunter | 1 | 15 | 0 | 15 |
| F. Gore | 1 | 6 | 0 | 6 |
| B. Miller | 1 | 5 | 0 | 5 |
| Fumbles | ||||
| NO | LST | REC | YDS | |
| N. Bowman | 0 | 0 | 1 | 0 |
| D. Whitner | 0 | 0 | 1 | 0 |
| Kicking | ||||
| FG | LG | XP | PTS | |
| D. Akers | 3/6 | 43 | 2/2 | 11 |
| Punting | ||||
| NO | AVG | I20 | LG | |
| A. Lee | 3 | 45.3 | 1 | 58 |
| Kickoff Returns | ||||
| NO | AVG | TD | LG | |
| T. Ginn | 2 | 21.0 | 0 | 24 |
| Punt Returns | ||||
| NO | AVG | TD | LG | |
| T. Ginn | 4 | 4.0 | 0 | 10 |
| Defense | ||||
| T-A | SCK | INT | FF | |
| P. Willis | 6-1 | 0.0 | 1 | 1 |
| C. Rogers | 4-0 | 0.0 | 0 | 0 |
| N. Bowman | 3-0 | 0.0 | 0 | 0 |
| C. Culliver | 3-0 | 0.0 | 0 | 0 |
| A. Brooks | 2-0 | 1.0 | 0 | 0 |
| D. Whitner | 2-1 | 0.0 | 1 | 0 |
| D. Goldson | 2-0 | 0.0 | 1 | 0 |
| P. Haralson | 1-0 | 0.0 | 0 | 0 |
| A. Dixon | 1-0 | 0.0 | 0 | 0 |
| R. McDonald | 1-0 | 0.0 | 0 | 0 |
| T. Brown | 1-0 | 0.0 | 0 | 0 |
| C. Spillman | 1-0 | 0.0 | 0 | 0 |
| B. Costanzo | 1-0 | 0.0 | 0 | 0 |
| T. Gooden | 1-0 | 0.0 | 0 | 1 |
| S. Spencer | 1-0 | 0.0 | 0 | 0 |
| A. Smith | 1-1 | 1.0 | 0 | 0 |
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