| Passing | ||||
| CP/AT | YDS | TD | INT | |
| T. Pryor | 13/28 | 150 | 2 | 1 |
| Rushing | ||||
| ATT | YDS | TD | LG | |
| D. McFadden | 19 | 57 | 0 | 8 |
| T. Pryor | 9 | 49 | 1 | 9 |
| M. Goodson | 1 | 9 | 0 | 9 |
| Receiving | ||||
| REC | YDS | TD | LG | |
| R. Streater | 4 | 77 | 0 | 38 |
| B. Myers | 4 | 53 | 0 | 22 |
| D. Heyward-Bey | 2 | 13 | 1 | 9 |
| D. Moore | 1 | 5 | 1 | 5 |
| D. McFadden | 2 | 2 | 0 | 3 |
| Fumbles | ||||
| NO | LST | REC | YDS | |
| D. Moore | 1 | 0 | 1 | 0 |
| T. Pryor | 1 | 0 | 0 | 0 |
| Kicking | ||||
| FG | LG | XP | PTS | |
| S. Janikowski | 0/0 | 0 | 3/3 | 3 |
| Punting | ||||
| NO | AVG | I20 | LG | |
| S. Lechler | 6 | 46.2 | 1 | 58 |
| Kickoff Returns | ||||
| NO | AVG | TD | LG | |
| C. Francies | 2 | 23.0 | 0 | 25 |
| M. Goodson | 1 | 15.0 | 0 | 15 |
| Punt Returns | ||||
| NO | AVG | TD | LG | |
| D. Moore | 4 | 6.0 | 0 | 19 |
| Defense | ||||
| T-A | SCK | INT | FF | |
| L. Houston | 9-4 | 1.5 | 0 | 0 |
| O. Gaither | 5-1 | 0.0 | 0 | 0 |
| M. Burris | 5-2 | 0.0 | 0 | 0 |
| B. Ross | 4-1 | 0.0 | 0 | 0 |
| J. Hanson | 3-1 | 0.0 | 0 | 0 |
| M. Mitchell | 3-1 | 0.0 | 0 | 0 |
| T. Kelly | 3-2 | 0.0 | 0 | 0 |
| M. Shaughnessy | 2-0 | 0.0 | 0 | 0 |
| M. Giordano | 2-0 | 0.0 | 0 | 0 |
| D. Bryant | 1-2 | 0.5 | 0 | 0 |
| K. Clayton | 1-0 | 0.0 | 0 | 0 |
| M. Huff | 1-2 | 0.0 | 0 | 0 |
| K. Burnett | 1-0 | 0.0 | 0 | 0 |
| T. Jones | 1-0 | 0.0 | 0 | 0 |
| C. Chekwa | 1-0 | 0.0 | 0 | 0 |
| P. Wheeler | 1-1 | 0.0 | 0 | 0 |
| J. Condo | 0-1 | 0.0 | 0 | 0 |
| D. Ausberry | 0-1 | 0.0 | 0 | 0 |
| 1 | 2 | 3 | 4 | |
| Oakland | 0 | 7 | 0 | 14 |
| San Diego | 10 | 7 | 7 | 0 |
| 1st Quarter | ||
| TD @ 14:48 | Micheal Spurlock runs 99 yards for a kick return (Nick Novak kick is good). | |
| FG @ 4:11 | Nick Novak makes a 30 yard kick. Drive: 9 plays, 59 yards in 5:20. | |
| 2nd Quarter | ||
| TD @ 12:11 | Darrius Heyward-Bey catches a 9 yard pass from Terrelle Pryor (Sebastian Janikowski kick is good). Drive: 12 plays, 80 yards in 7:00. | |
| TD @ 2:48 | Antonio Gates catches an 11 yard pass from Philip Rivers (Nick Novak kick is good). Drive: 14 plays, 81 yards in 9:23. | |
| 3rd Quarter | ||
| TD @ 4:59 | Danario Alexander catches a 34 yard pass from Philip Rivers (Nick Novak kick is good). Drive: 4 plays, 47 yards in 2:11. | |
| 4th Quarter | ||
| TD @ 7:43 | Terrelle Pryor runs for 3 yards (Sebastian Janikowski kick is good). Drive: 8 plays, 76 yards in 5:19. | |
| TD @ 1:52 | Denarius Moore catches a 5 yard pass from Terrelle Pryor (Sebastian Janikowski kick is good). Drive: 3 plays, 11 yards in 0:53. | |
| 4th Quarter | |
| 4-6-SD 38 | (2:55) M.Scifres punt is BLOCKED by C.Francies, Center-K.Nelson, RECOVERED by OAK-K.Burnett at SD 11. K.Burnett to SD 11 for no gain (M.Ingram). |
| 1-10-SD 11 | (2:45) (Shotgun) T.Pryor pass short left to B.Myers to SD 2 for 9 yards (A.Gachkar). |
| 2-1-SD 2 | (2:14) D.McFadden up the middle to SD 1 for 1 yard (M.Gilchrist, A.Garay). |
| 1-1-SD 1 | (2:00) PENALTY on OAK-D.Ausberry, False Start, 4 yards, enforced at SD 1 - No Play. |
| 1-5-SD 5 | (2:00) (Shotgun) T.Pryor pass short right to D.Moore for 5 yards, TOUCHDOWN. |
| S.Janikowski extra point is GOOD, Center-J.Condo, Holder-S.Lechler. | |
| S.Janikowski kicks onside 12 yards from OAK 35 to OAK 47. M.Spurlock (didn't try to advance), dead ball declared at OAK 47 for no gain. | |
| 1-10-OAK 47 | (1:51) P.Rivers kneels, dead ball declared at OAK 48 for -1 yards. |
| 2-11-OAK 48 | (1:04) P.Rivers kneels, dead ball declared at OAK 49 for -1 yards. |
| 3-12-OAK 49 | (:26) P.Rivers kneels, dead ball declared at 50 for -1 yards. |
| Passing | ||||
| CP/AT | YDS | TD | INT | |
| P. Rivers | 13/17 | 151 | 2 | 0 |
| Rushing | ||||
| ATT | YDS | TD | LG | |
| J. Battle | 19 | 37 | 0 | 8 |
| R. Brown | 5 | 20 | 0 | 6 |
| C. Brinkley | 3 | 10 | 0 | 7 |
| E. Weddle | 1 | 6 | 0 | 6 |
| P. Rivers | 3 | -3 | 0 | -1 |
| Receiving | ||||
| REC | YDS | TD | LG | |
| E. Royal | 4 | 61 | 0 | 31 |
| D. Alexander | 1 | 34 | 1 | 34 |
| J. Battle | 4 | 31 | 0 | 11 |
| A. Gates | 2 | 15 | 1 | 11 |
| M. Spurlock | 1 | 7 | 0 | 7 |
| R. Brown | 1 | 3 | 0 | 3 |
| Fumbles | ||||
| NO | LST | REC | YDS | |
| Kicking | ||||
| FG | LG | XP | PTS | |
| N. Novak | 1/1 | 30 | 3/3 | 6 |
| Punting | ||||
| NO | AVG | I20 | LG | |
| M. Scifres | 5 | 50.0 | 0 | 58 |
| Kickoff Returns | ||||
| NO | AVG | TD | LG | |
| M. Spurlock | 2 | 58.5 | 1 | 99 |
| Punt Returns | ||||
| NO | AVG | TD | LG | |
| M. Spurlock | 2 | 7.5 | 0 | 10 |
| Defense | ||||
| T-A | SCK | INT | FF | |
| E. Weddle | 7-1 | 0.0 | 0 | 0 |
| D. Williams | 6-1 | 0.0 | 0 | 0 |
| A. Gachkar | 5-1 | 0.0 | 0 | 0 |
| B. Bird | 5-2 | 0.0 | 0 | 0 |
| M. Gilchrist | 4-1 | 0.0 | 0 | 0 |
| M. Ingram | 3-1 | 0.0 | 0 | 0 |
| A. Cason | 3-3 | 0.0 | 0 | 0 |
| C. Lynch | 3-0 | 0.0 | 0 | 0 |
| C. Thomas | 2-1 | 0.0 | 0 | 0 |
| C. Liuget | 2-1 | 0.0 | 0 | 0 |
| J. Johnson | 1-0 | 0.0 | 0 | 0 |
| S. Wright | 1-0 | 0.0 | 0 | 0 |
| L. English | 1-0 | 0.0 | 0 | 0 |
| D. Rosario | 1-0 | 0.0 | 0 | 0 |
| T. Spikes | 1-0 | 0.0 | 0 | 0 |
| Q. Jammer | 1-0 | 0.0 | 1 | 0 |
| A. Garay | 1-1 | 0.0 | 0 | 0 |
| K. Reyes | 0-3 | 0.0 | 0 | 0 |
| S. Phillips | 0-1 | 0.0 | 0 | 0 |
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