| First Quarter | |
| Buffalo Bills at 15:00 | |
| R.Lindell kicks 39 yards from BUF 35 to HST 26. S.Keo (didn't try to advance) to HST 26 for no gain (R.Brooks). | |
| Houston Texans at 14:57 | |
| 1-10-HOU26 | (14:57) A.Foster left tackle pushed ob at HST 36 for 10 yards (S.Gilmore). |
| 1-10-HOU36 | (14:29) A.Foster left tackle to HST 37 for 1 yard (K.Sheppard). |
| 2-9-HOU37 | (13:54) A.Foster up the middle to HST 42 for 5 yards (M.Williams). |
| 3-4-HOU42 | (13:14) (Shotgun) M.Schaub pass incomplete short middle to O.Daniels. |
| 4-4-HOU42 | (13:09) D.Jones punts 49 yards to BUF 9, Center-J.Weeks, fair catch by L.McKelvin. PENALTY on HST, Illegal Formation, 5 yards, enforced at HST 42 - No Play. |
| 4-9-HOU37 | (12:59) PENALTY on HST-B.Ruud, False Start, 5 yards, enforced at HST 37 - No Play. |
| 4-14-HOU32 | (12:59) D.Jones punts 50 yards to BUF 18, Center-J.Weeks. L.McKelvin to BUF 27 for 9 yards (J.Weeks; S.Keo). (The punt hang time was 5.1 seconds.) |
| Buffalo Bills at 12:46 | |
| 1-10-BUF27 | (12:46) (Shotgun) R.Fitzpatrick pass incomplete short middle to D.Jones (S.Cody). |
| 2-10-BUF27 | (12:41) (Shotgun) F.Jackson right tackle to BUF 28 for 1 yard (S.Cody; C.Barwin). |
| 3-9-BUF28 | (11:57) (Shotgun) R.Fitzpatrick pass short middle to St.Johnson to BUF 42 for 14 yards (B.McCain). |
| 1-10-BUF42 | (11:14) F.Jackson right end to BUF 41 for -1 yards (J.Watt). |
| 2-11-BUF41 | (10:29) (Shotgun) R.Fitzpatrick pass incomplete deep left to St.Johnson. |
| 3-11-BUF41 | (10:24) (Shotgun) R.Fitzpatrick pass short middle to F.Jackson to BUF 44 for 3 yards (C.Barwin). |
| 4-8-BUF44 | (9:47) S.Powell punts 52 yards to HST 4, Center-G.Sanborn, downed by BUF-R.Martin. (The punt hang time was 3.4 seconds.) |
| Houston Texans at 09:36 | |
| 1-10-HOU4 | (9:36) A.Foster left end to HST 4 for no gain (J.Byrd). |
| 2-10-HOU4 | (8:55) M.Schaub pass incomplete deep left to O.Daniels. |
| 3-10-HOU4 | (8:49) (Shotgun) A.Foster up the middle to HST 15 for 11 yards (G.Wilson). |
| 1-10-HOU15 | (8:12) M.Schaub pass deep middle to K.Walter to HST 36 for 21 yards (K.Sheppard). PENALTY on HST-J.Forsett, Offensive Holding, 7 yards, enforced at HST 15 - No Play. |
| 1-17-HOU8 | (7:36) (Shotgun) M.Schaub pass short right to A.Johnson to HST 11 for 3 yards (N.Barnett). PENALTY on BUF-S.Merriman, Defensive Offside, 5 yards, enforced at HST 8 - No Play. |
| 1-12-HOU13 | (7:08) M.Schaub pass incomplete short right to A.Foster. |
| 2-12-HOU13 | (7:03) (Shotgun) M.Schaub pass short right to A.Johnson pushed ob at HST 26 for 13 yards (A.Williams). |
| 1-10-HOU26 | (6:39) M.Schaub pass short right to O.Daniels pushed ob at HST 34 for 8 yards (N.Bradham). |
| 2-2-HOU34 | (6:00) J.Forsett left tackle to HST 34 for no gain (K.Sheppard; A.Carrington). |
| 3-2-HOU34 | (5:17) (Shotgun) M.Schaub sacked at HST 26 for -8 yards (K.Moore). |
| 4-10-HOU26 | (4:52) D.Jones punts 57 yards to BUF 17, Center-J.Weeks. L.McKelvin to BUF 26 for 9 yards (S.Keo). (The punt hang time was 4.6 seconds.) |
| Buffalo Bills at 04:40 | |
| 1-10-BUF26 | (4:40) C.Spiller up the middle to BUF 29 for 3 yards (T.Dobbins; J.Crick). |
| 2-7-BUF29 | (3:56) (Shotgun) R.Fitzpatrick pass short left to St.Johnson to BUF 35 for 6 yards (J.Joseph). |
| 3-1-BUF35 | (3:25) C.Spiller up the middle to BUF 35 for no gain (E.Mitchell). |
| 4-1-BUF35 | (2:47) S.Powell punts 50 yards to HST 15, Center-G.Sanborn. K.Martin to HST 23 for 8 yards (B.Smith). |
| Houston Texans at 02:36 | |
| 1-10-HOU23 | (2:36) M.Schaub pass deep right to K.Walter to HST 41 for 18 yards (D.Searcy). |
| 1-10-HOU41 | (1:53) M.Schaub pass short left to A.Johnson to HST 47 for 6 yards (N.Barnett). |
| 2-4-HOU47 | (1:17) A.Foster left end pushed ob at BUF 39 for 14 yards (J.Byrd). |
| 1-10-BUF39 | (:44) M.Schaub pass deep right to O.Daniels for 39 yards, TOUCHDOWN. |
| S.Graham extra point is GOOD, Center-J.Weeks, Holder-D.Jones. | |
| BUF 0 HOU 7, Plays: 4 Yards: 77 Possession: 2:00. | |
| Houston Texans at 00:36 | |
| S.Graham kicks 61 yards from HST 35 to BUF 4. L.McKelvin pushed ob at BUF 26 for 22 yards (A.Ball). | |
| Buffalo Bills at 00:30 | |
| 1-10-BUF26 | (:30) (Shotgun) R.Fitzpatrick pass short right to St.Johnson to BUF 35 for 9 yards (G.Quin). |
| Second Quarter | |
| Buffalo Bills continued... | |
| 2-1-BUF35 | (15:00) (Shotgun) C.Spiller up the middle to BUF 40 for 5 yards (W.Mercilus; G.Quin). |
| 1-10-BUF40 | (14:18) (Shotgun) PENALTY on HST-A.Smith, Encroachment, 5 yards, enforced at BUF 40 - No Play. |
| 1-5-BUF45 | (14:18) (Shotgun) R.Fitzpatrick pass short middle to D.Jones to HST 47 for 8 yards (B.James). |
| 1-10-HOU47 | (13:41) (Shotgun) R.Fitzpatrick pass short middle to C.Spiller pushed ob at HST 19 for 28 yards (T.Dobbins). |
| 1-10-HOU19 | (12:57) R.Fitzpatrick pass short left to F.Jackson to HST 20 for -1 yards (T.Dobbins). |
| 2-11-HOU20 | (12:09) (Shotgun) R.Fitzpatrick sacked at HST 21 for -1 yards (C.Barwin). |
| 3-12-HOU21 | (11:23) (Shotgun) R.Fitzpatrick scrambles up the middle to HST 18 for 3 yards (B.Reed). |
| 4-9-HOU18 | (10:35) R.Lindell 37 yard field goal is No Good, Wide Right, Center-G.Sanborn, Holder-S.Powell. |
| Houston Texans at 10:31 | |
| 1-10-HOU27 | (10:31) M.Schaub pass short right to A.Johnson to HST 40 for 13 yards (A.Williams). |
| 1-10-HOU40 | (9:50) A.Foster right tackle to BUF 39 for 21 yards (N.Bradham; A.Williams). |
| 1-10-BUF39 | (9:07) PENALTY on HST-A.Caldwell, False Start, 5 yards, enforced at BUF 39 - No Play. |
| 1-15-BUF44 | (8:50) M.Schaub pass short middle to J.Casey to BUF 20 for 24 yards (C.Kelsay) [K.Sheppard]. |
| 1-10-BUF20 | (8:07) K.Martin left end to BUF 19 for 1 yard (J.Byrd). |
| 2-9-BUF19 | (7:21) M.Schaub sacked at BUF 23 for -4 yards (M.Williams). Penalty on HST-D.Brown, Offensive Holding, declined. |
| 3-13-BUF23 | (7:01) (Shotgun) PENALTY on HST-D.Newton, False Start, 5 yards, enforced at BUF 23 - No Play. |
| 3-18-BUF28 | (6:37) (Shotgun) M.Schaub pass incomplete short middle to K.Walter (J.Rogers). |
| Buffalo Bills at 06:22 | |
| 1-10-BUF36 | (6:22) F.Jackson up the middle to BUF 49 for 13 yards (G.Quin). |
| 1-10-BUF49 | (5:36) (Shotgun) R.Fitzpatrick pass short middle to D.Dickerson to HST 38 for 13 yards (T.Dobbins). HST-B.James was injured during the play. His return is Probable. |
| 1-10-HOU38 | (5:08) R.Fitzpatrick pass short right to D.Jones to HST 24 for 14 yards (J.Joseph). |
| 1-10-HOU24 | (4:26) F.Jackson right guard to HST 20 for 4 yards (G.Quin; J.Watt). |
| 2-6-HOU20 | (3:45) (Shotgun) B.Smith right guard to HST 20 for no gain (J.Watt). (#16 Smith received the direct snap.) |
| 3-6-HOU20 | (3:00) (Shotgun) R.Fitzpatrick pass short right to S.Chandler to HST 12 for 8 yards (G.Quin). |
| 1-10-HOU12 | (2:21) (Shotgun) F.Jackson up the middle to HST 10 for 2 yards (J.Watt). |
| 2-8-HOU10 | (2:00) (Shotgun) PENALTY on BUF-A.Levitre, False Start, 5 yards, enforced at HST 10 - No Play. |
| 2-13-HOU15 | (2:00) (Shotgun) R.Fitzpatrick pass short left to F.Jackson to HST 11 for 4 yards (Q.Demps). |
| 3-9-HOU11 | (1:54) R.Fitzpatrick pass short middle to D.Jones to HST 4 for 7 yards (B.McCain). |
| 4-2-HOU4 | (1:45) R.Lindell 22 yard field goal is GOOD, Center-G.Sanborn, Holder-S.Powell. |
| BUF 3 HOU 7, Plays: 10 Yards: 60 Possession: 4:40. | |
| Buffalo Bills at 01:42 | |
| R.Lindell kicks 67 yards from BUF 35 to HST -2. K.Martin to HST 26 for 28 yards (N.Bradham). | |
| Houston Texans at 01:36 | |
| 1-10-HOU26 | (1:36) (Shotgun) M.Schaub pass incomplete short middle to O.Daniels. |
| 2-10-HOU26 | (1:30) (Shotgun) M.Schaub pass short middle to O.Daniels to HST 29 for 3 yards (N.Barnett). |
| 3-7-HOU29 | (1:10) (Shotgun) M.Schaub pass incomplete short left to O.Daniels (B.Scott). |
| 4-7-HOU29 | (1:05) D.Jones punts 58 yards to BUF 13, Center-J.Weeks. L.McKelvin pushed ob at BUF 33 for 20 yards (B.McCain). (The punt hang time was 4.5 seconds.) |
| Buffalo Bills at 00:52 | |
| 1-10-BUF33 | (:52) (Shotgun) R.Fitzpatrick pass incomplete short right to T.Graham. |
| 2-10-BUF33 | (:48) (Shotgun) R.Fitzpatrick pass short left to C.Spiller to BUF 45 for 12 yards (Q.Demps). |
| 1-10-BUF45 | (:28) (Shotgun) R.Fitzpatrick pass short right to D.Jones pushed ob at HST 36 for 19 yards (D.Manning). |
| 1-10-HOU36 | (:22) (Shotgun) C.Spiller right end pushed ob at HST 14 for 22 yards (J.Joseph). |
| 1-10-HOU14 | (:16) (Shotgun) R.Fitzpatrick sacked at HST 20 for -6 yards (J.Watt). |
| 2-16-HOU20 | (:09) R.Lindell 38 yard field goal is GOOD, Center-G.Sanborn, Holder-S.Powell. |
| BUF 6 HOU 7, Plays: 6 Yards: 47 Possession: 0:47. | |
| Buffalo Bills at 00:05 | |
| R.Lindell kicks 51 yards from BUF 35 to HST 14. K.Martin ran ob at HST 23 for 9 yards. | |
| Houston Texans at 00:02 | |
| 1-10-HOU23 | (:02) M.Schaub kneels to HST 22 for -1 yards. |
| Third Quarter | |
| Houston Texans at 15:00 | |
| S.Graham kicks 39 yards from HST 35 to BUF 26. A.Carrington (didn't try to advance) to BUF 26 for no gain (Q.Demps). | |
| Buffalo Bills at 14:58 | |
| 1-10-BUF26 | (14:58) (Shotgun) R.Fitzpatrick pass incomplete short left to S.Chandler (B.James). |
| 2-10-BUF26 | (14:52) (Shotgun) R.Fitzpatrick pass incomplete deep right to F.Jackson [J.Watt]. |
| 3-10-BUF26 | (14:47) (Shotgun) R.Fitzpatrick pass incomplete deep left to St.Johnson. |
| 4-10-BUF26 | (14:41) S.Powell punts 43 yards to HST 31, Center-G.Sanborn. K.Martin pushed ob at BUF 43 for 26 yards (B.Smith). (The punt hang time was 4.3 seconds.) |
| Houston Texans at 14:27 | |
| 1-10-BUF43 | (14:27) A.Foster right guard to BUF 42 for 1 yard (K.Williams). |
| 2-9-BUF42 | (13:59) A.Foster left end to BUF 38 for 4 yards (D.Searcy). |
| 3-5-BUF38 | (13:19) M.Schaub pass deep right to A.Johnson to BUF 4 for 34 yards (A.Williams). BUF-A.Williams was injured during the play. His return is Doubtful. |
| 1-4-BUF4 | (12:48) A.Foster up the middle to BUF 3 for 1 yard (M.Williams; K.Sheppard). |
| 2-3-BUF3 | (12:16) A.Foster left tackle for 3 yards, TOUCHDOWN. |
| S.Graham extra point is GOOD, Center-J.Weeks, Holder-D.Jones. | |
| BUF 6 HOU 14, Plays: 5 Yards: 43 Possession: 2:16. | |
| Houston Texans at 12:11 | |
| S.Graham kicks 57 yards from HST 35 to BUF 8. L.McKelvin to BUF 23 for 15 yards (Q.Demps). | |
| Buffalo Bills at 12:04 | |
| 1-10-BUF23 | (12:04) (Shotgun) C.Spiller up the middle to BUF 26 for 3 yards (B.Reed). |
| 2-7-BUF26 | (11:19) R.Fitzpatrick pass short left to D.Jones to BUF 41 for 15 yards (J.Joseph). |
| 1-10-BUF41 | (10:36) (Shotgun) R.Fitzpatrick pass short left to F.Jackson to BUF 44 for 3 yards (T.Dobbins). |
| 2-7-BUF44 | (9:50) (Shotgun) R.Fitzpatrick pass deep left to S.Chandler to HST 29 for 27 yards (D.Manning). |
| 1-10-HOU29 | (9:03) (Shotgun) F.Jackson left guard to HST 27 for 2 yards (S.Cody). HST-S.Cody was injured during the play. |
| 2-8-HOU27 | (8:23) (Shotgun) C.Spiller right end pushed ob at HST 21 for 6 yards (B.James). |
| 3-2-HOU21 | (7:50) R.Fitzpatrick pass incomplete short left to St.Johnson (J.Joseph). |
| 4-2-HOU21 | (7:45) R.Lindell 39 yard field goal is GOOD, Center-G.Sanborn, Holder-S.Powell. |
| BUF 9 HOU 14, Plays: 8 Yards: 56 Possession: 4:30. | |
| Buffalo Bills at 07:41 | |
| R.Lindell kicks 66 yards from BUF 35 to HST -1. K.Martin to HST 24 for 25 yards (B.Scott). | |
| Houston Texans at 07:34 | |
| 1-10-HOU24 | (7:34) A.Foster up the middle to HST 25 for 1 yard (G.Wilson). |
| 2-9-HOU25 | (7:03) M.Schaub pass short right to A.Johnson to HST 36 for 11 yards (S.Gilmore). |
| 1-10-HOU36 | (6:24) A.Foster left tackle to HST 36 for no gain (K.Sheppard). PENALTY on HST-C.Myers, Offensive Holding, 10 yards, enforced at HST 36 - No Play. |
| 1-20-HOU26 | (6:05) M.Schaub pass incomplete deep left to A.Johnson (S.Gilmore). |
| 2-20-HOU26 | (5:59) A.Foster right tackle to HST 28 for 2 yards (M.Dareus; K.Williams). |
| 3-18-HOU28 | (5:16) (Shotgun) M.Schaub pass short right to J.Casey to HST 41 for 13 yards (J.Byrd). |
| 4-5-HOU41 | (4:41) D.Jones punts 39 yards to BUF 20, Center-J.Weeks, out of bounds. (The punt hang time was 4.2 seconds.) |
| Buffalo Bills at 04:32 | |
| 1-10-BUF20 | (4:32) (Shotgun) R.Fitzpatrick pass short right to T.Graham to BUF 19 for -1 yards (D.Manning). |
| 2-11-BUF19 | (3:48) (Shotgun) R.Fitzpatrick pass short left to C.Spiller pushed ob at BUF 23 for 4 yards (Q.Demps). |
| 3-7-BUF23 | (3:11) (Shotgun) R.Fitzpatrick pass incomplete short middle to D.Jones (B.McCain). |
| 4-7-BUF23 | (3:04) S.Powell punts 45 yards to HST 32, Center-G.Sanborn, fair catch by K.Martin. (The punt hang time was 4.3 seconds.) |
| Houston Texans at 02:55 | |
| 1-10-HOU32 | (2:55) M.Schaub pass short left to K.Walter to HST 42 for 10 yards (L.McKelvin). |
| 1-10-HOU42 | (2:15) A.Foster left tackle to HST 38 for -4 yards (K.Williams). |
| 2-14-HOU38 | (1:34) M.Schaub pass short middle to O.Daniels to 50 for 12 yards (G.Wilson; K.Sheppard). |
| 3-2-50 | (:53) M.Schaub pass short right to A.Johnson to BUF 36 for 14 yards (M.Williams). |
| 1-10-BUF36 | (:13) A.Foster right tackle to BUF 28 for 8 yards (N.Bradham). |
| Fourth Quarter | |
| Houston Texans continued... | |
| 2-2-BUF28 | (15:00) A.Foster right guard to BUF 25 for 3 yards (M.Dareus; C.Kelsay). |
| 1-10-BUF25 | (14:20) A.Foster right tackle to BUF 27 for -2 yards (N.Barnett). |
| 2-12-BUF27 | (13:39) M.Schaub pass short left to A.Johnson to BUF 9 for 18 yards (G.Wilson). |
| 1-9-BUF9 | (12:56) A.Foster left tackle to BUF 11 for -2 yards (N.Bradham). |
| 2-11-BUF11 | (12:18) M.Schaub pass short right to G.Graham to BUF 5 for 6 yards (N.Bradham). |
| 3-5-BUF5 | (11:32) (Shotgun) M.Schaub pass short right to G.Graham for 5 yards, TOUCHDOWN. |
| S.Graham extra point is GOOD, Center-J.Weeks, Holder-D.Jones. | |
| BUF 9 HOU 21, Plays: 11 Yards: 68 Possession: 6:30. | |
| Houston Texans at 11:25 | |
| S.Graham kicks 49 yards from HST 35 to BUF 16. B.Smith to BUF 31 for 15 yards (J.Nading). | |
| Buffalo Bills at 11:16 | |
| 1-10-BUF31 | (11:16) (Shotgun) R.Fitzpatrick pass short middle to D.Jones to BUF 33 for 2 yards (B.James). |
| 2-8-BUF33 | (10:37) (Shotgun) R.Fitzpatrick pass incomplete short right to F.Jackson (J.Crick). |
| 3-8-BUF33 | (10:32) (Shotgun) R.Fitzpatrick pass incomplete short left to S.Chandler [J.Watt]. |
| 4-8-BUF33 | (10:27) S.Powell punts 57 yards to HST 10, Center-G.Sanborn, out of bounds. (The punt hang time was 4.8 seconds.) |
| Houston Texans at 10:19 | |
| 1-10-HOU10 | (10:19) A.Foster up the middle to HST 13 for 3 yards (M.Dareus). |
| 2-7-HOU13 | (9:43) M.Schaub pass short middle to A.Johnson to HST 22 for 9 yards (L.McKelvin). |
| 1-10-HOU22 | (9:00) A.Foster left guard to HST 27 for 5 yards (K.Sheppard; K.Williams). |
| 2-5-HOU27 | (8:17) A.Foster left end pushed ob at HST 33 for 6 yards (S.Gilmore). |
| 1-10-HOU33 | (7:44) A.Foster right tackle to HST 35 for 2 yards (Sp.Johnson). |
| 2-8-HOU35 | (7:02) M.Schaub pass short left to J.Casey to HST 47 for 12 yards (K.Sheppard). |
| 1-10-HOU47 | (6:15) A.Foster left end pushed ob at BUF 34 for 19 yards (L.McKelvin). |
| 1-10-BUF34 | (5:37) J.Forsett left tackle to BUF 34 for no gain (M.Williams). |
| 2-10-BUF34 | (4:51) J.Forsett left end to BUF 29 for 5 yards (D.Searcy). |
| 3-5-BUF29 | (4:42) (Shotgun) A.Foster right guard to BUF 30 for -1 yards (B.Scott; N.Barnett). |
| 4-6-BUF30 | (4:38) M.Schaub pass incomplete deep left to A.Johnson. |
| Buffalo Bills at 04:31 | |
| 1-10-BUF30 | (4:31) (Shotgun) R.Fitzpatrick pass incomplete deep left to St.Johnson (Q.Demps). |
| 2-10-BUF30 | (4:24) (Shotgun) R.Fitzpatrick pass short middle to F.Jackson to BUF 35 for 5 yards (G.Quin, D.Manning) [C.Barwin]. |
| 3-5-BUF35 | (3:45) (Shotgun) R.Fitzpatrick pass incomplete short left to R.Martin [J.Watt]. |
| 4-5-BUF35 | (3:41) (Shotgun) R.Fitzpatrick pass short middle to S.Chandler pushed ob at HST 49 for 16 yards (K.Jackson) [C.Barwin]. |
| 1-10-HOU49 | (3:34) (Shotgun) R.Fitzpatrick pass incomplete short right to D.Jones. |
| 2-10-HOU49 | (3:29) (Shotgun) R.Fitzpatrick scrambles left end pushed ob at HST 38 for 11 yards (K.Jackson). |
| 1-10-HOU38 | (3:21) (Shotgun) R.Fitzpatrick scrambles left end to HST 34 for 4 yards (W.Mercilus). FUMBLES (W.Mercilus), RECOVERED by HST-Q.Demps at HST 32. Q.Demps to HST 32 for no gain (S.Chandler). |
| Houston Texans at 03:12 | |
| 1-10-HOU32 | (3:12) J.Forsett left guard to HST 31 for -1 yards (G.Wilson; M.Williams). |
| 2-11-HOU31 | (2:30) J.Forsett right guard to HST 37 for 6 yards (N.Bradham; J.Byrd). |
| 3-5-HOU37 | (2:00) J.Forsett left tackle to HST 34 for -3 yards (M.Williams). |
| 4-8-HOU34 | (1:15) D.Jones punts 43 yards to BUF 23, Center-J.Weeks. L.McKelvin to BUF 22 for -1 yards (A.Ball). (The punt hang time was 4.0 seconds.) |
| Buffalo Bills at 01:06 | |
| 1-10-BUF22 | (1:06) (Shotgun) R.Fitzpatrick pass short middle to C.Spiller to BUF 28 for 6 yards (B.McCain) [C.Barwin]. |
| 2-4-BUF28 | (:58) (Shotgun) R.Fitzpatrick pass short middle to T.Graham to BUF 33 for 5 yards (C.Barwin) [J.Watt]. |
| 1-10-BUF33 | (:33) (Shotgun) R.Fitzpatrick pass short middle to C.Spiller pushed ob at BUF 46 for 13 yards (Q.Demps). |
| 1-10-BUF46 | (:25) (Shotgun) PENALTY on BUF-C.Glenn, False Start, 5 yards, enforced at BUF 46 - No Play. |
| 1-15-BUF41 | (:25) (Shotgun) R.Fitzpatrick sacked at BUF 39 for -2 yards (W.Mercilus). |
