| First Quarter | |
| San Francisco 49ers at 15:00 | |
| 1-10-SF35 | (15:00) David Akers kicked the ball for 65 yards. Touchback |
| Atlanta Falcons at 15:00 | |
| 1-10-ATL20 | (15:00) Michael Turner rushed for 3 yards. |
| 2-7-ATL23 | (14:18) Matt Ryan passed to Julio Jones for 13 yards. |
| 1-10-ATL36 | (13:41) Michael Turner rushed for 1 yard. |
| 2-9-ATL37 | (13:00) Matt Ryan passed incomplete to Roddy White. |
| 3-9-ATL37 | (12:55) Matt Ryan passed to Roddy White for 16 yards. |
| 1-10-SF47 | (12:11) Jacquizz Rodgers rushed for 1 yard. |
| 2-9-SF46 | (11:24) Touchdown. Matt Ryan passed to Julio Jones for 46 yards. |
| (11:24) Matt Bryant made the extra point. | |
| SF 0 ATL 7, Plays: 7 Yards: 80 Possession: 03:36. | |
| Atlanta Falcons at 11:24 | |
| 1-1-ATL35 | (11:24) Matt Bosher kicked the ball for 65 yards. Touchback |
| San Francisco 49ers at 11:24 | |
| 1-10-SF20 | (11:24) Colin Kaepernick passed to Michael Crabtree for 1 yard. |
| 2-9-SF21 | (10:44) Frank Gore rushed for no gain. |
| 3-9-SF21 | (10:03) Colin Kaepernick passed incomplete to Vernon Davis. |
| 4-9-SF21 | (9:57) Andy Lee punted for 62 yards. Harry Douglas returned a punt for 1 yard. |
| Atlanta Falcons at 9:57 | |
| 1-10-ATL18 | (9:43) Matt Ryan passed to Julio Jones for 8 yards. |
| 2-2-ATL26 | (9:07) Michael Turner rushed for 3 yards. |
| 1-10-ATL29 | (8:27) Matt Ryan passed to Julio Jones for 6 yards. |
| 2-4-ATL35 | (7:46) Matt Ryan passed to Tony Gonzalez for 5 yards. |
| 1-10-ATL40 | (7:08) Matt Ryan passed to Roddy White for 10 yards. |
| 1-10-50 | (6:26) Michael Turner rushed for no gain. |
| 2-10-50 | (5:45) Matt Ryan passed incomplete to Julio Jones. |
| 3-10-50 | (5:38) Matt Ryan passed to Julio Jones for 27 yards. |
| 1-10-SF23 | (4:53) Jacquizz Rodgers lost 2 yards. |
| 2-12-SF25 | (4:12) Matt Ryan passed to Tony Gonzalez for 8 yards. |
| 3-4-SF17 | (3:28) Matt Ryan passed incomplete to Jacquizz Rodgers. |
| 4-4-SF17 | (3:20) Matt Bryant made a field goal of 35 yards. |
| SF 0 ATL 10, Plays: 11 Yards: 65 Possession: 06:37. | |
| Atlanta Falcons at 3:20 | |
| 1-10-ATL35 | (3:20) Matt Bosher kicked the ball for 70 yards. LaMichael James returned the kick for 25 yards. |
| San Francisco 49ers at 3:20 | |
| 1-10-SF20 | (3:12) Colin Kaepernick passed incomplete to Randy Moss. |
| 2-10-SF20 | (3:08) Frank Gore rushed for 6 yards. |
| 3-4-SF26 | (2:28) Corey Peters sacked Colin Kaepernick for a loss of 9 yards. |
| 4-13-SF17 | (2:28) Andy Lee punted for 46 yards. Harry Douglas returned a punt for 6 yards. |
| Atlanta Falcons at 2:28 | |
| 1-10-ATL43 | (1:49) Michael Turner rushed for 4 yards. |
| 2-6-ATL47 | (1:10) Michael Turner rushed for 10 yards. |
| 1-10-SF43 | (0:26) Matt Ryan passed to Roddy White for 23 yards. |
| 1-10-SF20 | (14:57) Touchdown. Matt Ryan passed to Julio Jones for 20 yards. |
| Second Quarter | |
| Atlanta Falcons continued... | |
| (14:57) Matt Bryant made the extra point. | |
| SF 0 ATL 17, Plays: 4 Yards: 57 Possession: 02:31. | |
| Atlanta Falcons at 14:57 | |
| 1-1-ATL35 | (14:57) Matt Bosher kicked the ball for 65 yards. Touchback |
| San Francisco 49ers at 14:57 | |
| 1-10-SF20 | (14:54) Frank Gore rushed for 9 yards. |
| 2-1-SF29 | (14:19) Frank Gore rushed for 1 yard. |
| 1-10-SF30 | (13:37) Frank Gore rushed for 3 yards. |
| 2-7-SF33 | (12:54) Frank Gore rushed for 7 yards. |
| 1-10-SF40 | (12:19) Colin Kaepernick passed to Randy Moss for 8 yards. |
| 2-2-SF48 | (11:45) Colin Kaepernick passed to Michael Crabtree for 7 yards. |
| 1-10-ATL45 | (11:08) Colin Kaepernick passed to Michael Crabtree for 4 yards. |
| 2-6-ATL41 | (10:24) Colin Kaepernick passed to LaMichael James for 4 yards. |
| 3-2-ATL37 | (9:32) SF was penalized 5 yards. |
| 3-7-ATL42 | (9:08) Colin Kaepernick passed to Vernon Davis for 27 yards. |
| 1-10-ATL15 | (8:20) Colin Kaepernick passed incomplete to Michael Crabtree. |
| 2-10-ATL15 | (8:08) Touchdown. LaMichael James rushed for 15 yards. |
| (8:08) David Akers made the extra point. | |
| SF 7 ATL 17, Plays: 11 Yards: 75 Possession: 06:49. | |
| San Francisco 49ers at 8:08 | |
| 1-1-SF35 | (8:08) David Akers kicked the ball for 65 yards. Touchback |
| Atlanta Falcons at 8:08 | |
| 1-10-ATL20 | (8:08) Matt Ryan passed to Roddy White for 14 yards. |
| 1-10-ATL34 | (7:27) Michael Turner rushed for 6 yards. |
| 2-4-ATL40 | (6:40) Matt Ryan passed incomplete to Jacquizz Rodgers. |
| 3-4-ATL40 | (6:36) Matt Ryan passed incomplete to Jacquizz Rodgers. |
| 4-4-ATL40 | (6:32) Matt Bosher punted for 42 yards. Ted Ginn made a faircatch. |
| San Francisco 49ers at 6:32 | |
| 1-10-SF18 | (6:24) SF was penalized 9 yards. |
| 1-19-SF9 | (5:54) LaMichael James rushed for 3 yards. |
| 2-16-SF12 | (5:12) Colin Kaepernick passed to Vernon Davis for 19 yards. |
| 1-10-SF31 | (4:25) Frank Gore rushed for no gain. |
| 2-10-SF31 | (3:47) Colin Kaepernick rushed for 23 yards. |
| 1-10-ATL46 | (3:00) Frank Gore rushed for 2 yards. ATL was penalized 15 yards. |
| 1-10-ATL29 | (2:28) Colin Kaepernick passed to Vernon Davis for 25 yards. |
| 1-0-ATL4 | (1:55) Touchdown. Colin Kaepernick passed to Vernon Davis for 4 yards. |
| (1:55) David Akers made the extra point. | |
| SF 14 ATL 17, Plays: 7 Yards: 76 Possession: 04:37. | |
| San Francisco 49ers at 1:55 | |
| 1-1-SF35 | (1:55) David Akers kicked the ball for 65 yards. Touchback |
| Atlanta Falcons at 1:55 | |
| 1-10-ATL20 | (1:55) Matt Ryan passed to Roddy White for 15 yards. |
| 1-10-ATL35 | (1:33) Matt Ryan passed incomplete to Roddy White. |
| 2-10-ATL35 | (1:04) Matt Ryan passed incomplete to Tony Gonzalez. |
| 3-10-ATL35 | (1:08) SF was penalized 5 yards. |
| 1-10-SF44 | (1:04) Matt Ryan passed to Roddy White for 13 yards. |
| 1-10-SF31 | (0:57) Matt Ryan passed to Julio Jones for 15 yards. |
| 1-10-SF16 | (0:37) Matt Ryan passed to Tony Gonzalez for 6 yards. |
| 2-4-SF10 | (0:25) Touchdown. Matt Ryan passed to Tony Gonzalez for 10 yards. |
| (0:25) Matt Bryant made the extra point. | |
| SF 14 ATL 24, Plays: 7 Yards: 75 Possession: 01:30. | |
| Atlanta Falcons at 0:25 | |
| 1-1-ATL30 | (0:25) Matt Bosher kicked the ball for 69 yards. LaMichael James returned the kick for 19 yards. |
| San Francisco 49ers at 0:25 | |
| 1-10-SF15 | (0:19) LaMichael James rushed for 1 yard. |
| Atlanta Falcons at 0:19 | |
| 2-9-SF35 | (15:00) Matt Bosher kicked the ball for 67 yards. LaMichael James returned the kick for 20 yards. |
| Third Quarter | |
| San Francisco 49ers at 15:00 | |
| 1-10-SF18 | (14:55) Colin Kaepernick passed to Randy Moss for 21 yards. |
| 1-10-SF39 | (14:27) Frank Gore rushed for 6 yards. |
| 2-4-SF45 | (13:41) Frank Gore rushed for 11 yards. |
| 1-10-ATL44 | (13:00) Frank Gore rushed for 2 yards. |
| 2-8-ATL42 | (12:14) Colin Kaepernick passed to Delanie Walker for 20 yards. |
| 1-10-ATL22 | (11:34) Colin Kaepernick passed to Randy Moss for 17 yards. |
| 1-0-ATL5 | (10:47) Touchdown. Frank Gore rushed for 5 yards. |
| (10:47) David Akers made the extra point. | |
| SF 21 ATL 24, Plays: 7 Yards: 82 Possession: 04:13. | |
| San Francisco 49ers at 10:47 | |
| 1-1-SF35 | (10:47) David Akers kicked the ball for 65 yards. Touchback |
| Atlanta Falcons at 10:47 | |
| 1-10-ATL20 | (10:47) Michael Turner rushed for 3 yards. |
| 2-7-ATL23 | (10:05) Matt Ryan passed to Tony Gonzalez for 14 yards. |
| 1-10-ATL37 | (9:40) Jacquizz Rodgers rushed for 2 yards. |
| 2-8-ATL39 | (8:55) Matt Ryan passed to Tony Gonzalez for 14 yards. |
| 1-10-SF47 | (8:19) Isaac Sopoaga sacked Matt Ryan. |
| 2-10-SF47 | (7:46) Matt Ryan was intercepted. Chris Culliver returned the interception for 6 yards. |
| San Francisco 49ers at 7:46 | |
| 1-10-SF44 | (7:38) Colin Kaepernick passed to Vernon Davis for 31 yards. |
| 1-10-ATL25 | (7:14) Colin Kaepernick lost 2 yards. |
| 2-12-ATL27 | (6:43) LaMichael James rushed for 7 yards. |
| 3-5-ATL20 | (5:55) Colin Kaepernick passed incomplete to Chad Hall. |
| 4-5-ATL20 | (5:51) David Akers missed a field goal of 38 yards. |
| Atlanta Falcons at 5:51 | |
| 1-10-ATL28 | (5:44) Jacquizz Rodgers rushed for 7 yards. |
| 2-3-ATL35 | (5:06) Jason Snelling rushed for 12 yards. |
| 1-10-ATL47 | (4:20) Jacquizz Rodgers rushed for 9 yards. |
| 2-1-SF44 | (3:44) Jacquizz Rodgers rushed for 2 yards. |
| 1-10-SF42 | (3:04) Matt Ryan passed incomplete to Roddy White. |
| 2-10-SF42 | (2:57) Jason Snelling rushed for no gain. |
| 3-10-SF42 | (2:20) Matt Ryan passed to Julio Jones for 13 yards. |
| 1-10-SF29 | (1:42) Jacquizz Rodgers rushed for 1 yard. |
| 2-9-SF28 | (1:02) Matt Ryan rushed for no gain. Aldon Smith recovered a fumble from Matt Ryan and returned it for 0 yards. |
| San Francisco 49ers at 1:02 | |
| 1-10-SF37 | (0:55) Frank Gore rushed for 3 yards. |
| 2-7-SF40 | (0:15) Colin Kaepernick passed incomplete to Delanie Walker. |
| 3-7-SF40 | (0:10) ATL was penalized 15 yards. |
| 1-10-ATL45 | (0:05) Frank Gore rushed for 2 yards. |
| 2-8-ATL43 | (15:00) Colin Kaepernick passed to Michael Crabtree for 33 yards. |
| Fourth Quarter | |
| San Francisco 49ers continued... | |
| 1-0-ATL10 | (14:18) Frank Gore rushed for 5 yards. |
| 2-0-ATL5 | (14:18) Colin Kaepernick passed to Michael Crabtree for 4 yards. William Moore recovered a fumble from Michael Crabtree and returned it for 0 yards. |
| Atlanta Falcons at 14:18 | |
| 1-0-ATL1 | (13:24) Matt Ryan passed incomplete to Roddy White. |
| 2-0-ATL1 | (13:22) Mike Cox rushed for 4 yards. |
| 3-6-ATL5 | (12:40) Matt Ryan passed to Tony Gonzalez for 5 yards. |
| 4-1-ATL10 | (11:59) Matt Bosher punted for 48 yards. Ted Ginn returned a punt for 20 yards. |
| San Francisco 49ers at 11:59 | |
| 1-10-ATL38 | (11:46) Frank Gore rushed for 7 yards. |
| 2-3-ATL31 | (11:11) Frank Gore rushed for 2 yards. |
| 3-1-ATL29 | (10:29) Anthony Dixon rushed for 4 yards. |
| 1-10-ATL25 | (9:49) LaMichael James rushed for 8 yards. |
| 2-2-ATL17 | (9:12) Colin Kaepernick passed to Michael Crabtree for 8 yards. |
| 1-0-ATL9 | (8:23) Touchdown. Frank Gore rushed for 9 yards. |
| (8:23) David Akers made the extra point. | |
| SF 28 ATL 24, Plays: 6 Yards: 38 Possession: 03:36. | |
| San Francisco 49ers at 8:23 | |
| 1-1-SF35 | (8:23) David Akers kicked the ball for 65 yards. Touchback |
| Atlanta Falcons at 8:23 | |
| 1-10-ATL20 | (8:00) Matt Ryan passed to Roddy White for 9 yards. |
| 2-1-ATL29 | (7:45) Jacquizz Rodgers rushed for 2 yards. |
| 1-10-ATL31 | (7:03) Matt Ryan passed incomplete to Julio Jones. |
| 2-10-ATL31 | (7:01) Matt Ryan passed to Roddy White for 6 yards. |
| 3-4-ATL37 | (6:20) Matt Ryan passed to Julio Jones for 5 yards. |
| 1-10-ATL42 | (5:50) Matt Ryan rushed for 3 yards. |
| 2-7-ATL45 | (5:07) Matt Ryan passed to Julio Jones for 5 yards. |
| 3-2-50 | (4:20) Matt Ryan passed to Harry Douglas for 22 yards. |
| 1-10-SF28 | (3:53) Jacquizz Rodgers rushed for 9 yards. |
| 2-1-SF19 | (3:08) Matt Ryan passed to Harry Douglas for 3 yards. |
| 1-10-SF16 | (2:23) Jacquizz Rodgers rushed for 1 yard. |
| 2-9-SF15 | (2:00) Matt Ryan passed to Jason Snelling for 5 yards. |
| 3-4-SF10 | (1:15) Matt Ryan passed incomplete. |
| 4-4-SF10 | (1:10) Matt Ryan passed incomplete to Roddy White. |
| San Francisco 49ers at 1:10 | |
| 1-10-SF10 | (1:09) Frank Gore rushed for 3 yards. |
| 2-7-SF13 | (1:04) SF was penalized 5 yards. |
| 2-12-SF8 | (1:04) Frank Gore lost 3 yards. |
| 3-15-SF5 | (1:00) Frank Gore rushed for 10 yards. |
| 4-5-SF15 | (0:13) Andy Lee punted for 42 yards. Harry Douglas returned a punt for a 2 yard loss. |
| Atlanta Falcons at 0:13 | |
| 1-10-ATL41 | (0:05) Matt Ryan passed to Julio Jones for 24 yards. |
