Prosise (hand) is slated to be among the Seahawks' inactives for Sunday's game against the 49ers, Adam Schefter of ESPN reports.
Both Prosise and Thomas Rawls (lower leg) are expected to take a seat, opening the door for Christine Michael to take on the majority of the backfield reps in Week 3. If the preceding comes to fruition, fellow rookie Alex Collins will likely serve as the primary backup to Michael.
Rawls (lower leg) is listed as inactive Sunday versus the 49ers, Bob Condotta of The Seattle Times reports.
As relayed by Adam Schefter of ESPN on Sunday morning, Rawls will miss at least one game in order to tend to a lower leg contusion. With C.J. Prosise (hand) also on the inactive list, Christine Michael is poised to receive a plurality of touches out of the Seahawks' backfield in Week 3.
Nkemdiche (ankle) is unlikely to play Sunday against the Bills, according to Ian Rapoport of NFL Network.
Nkemdiche was unable to play last weekend due to the injury, and while there was a possibility he was going to give it a go Sunday, he has apparently not done enough in practice to warrant a game-day spot.