Nkemdiche (ankle) will take part in individual drills at Monday's practice, Lisa Matthews of the Cardinals' official site reports.
On Sunday, Tyrann Mathieu (knee), Justin Bethel (foot), and Frostee Rucker (foot) all made their first practice appearance of this term. Individual work was the expectation of each, but they also proceeded to participate in 11-on-11 drills. While only time will tell if Nkemdiche does the same, he's practicing earlier than expected, so it isn't out of the realm of possibility.
Fitzgerald (knee) will be held out of Wednesday's practice, Josh Weinfuss of ESPN.com reports.
After overextending himself in Sunday's session, Fitzgerald has seemingly been given an ultimatum by head coach Bruce Arians. The effort to avoid an aggravation of Fitzgerald's slight MCL sprain is admirable, especially with fellow wideout John Brown suffering through lingering concussion symptoms. Instead, rest and rehabilitation will dominate Fitzgerald's schedule for the time being.
Okafor has opted to avoid surgery and play with a torn biceps, Ian Rapoport of NFL Network reports.
Okafor sustained the injury in Tuesday's practice, the second such torn biceps in his three-year career. In 2013, surgery was ordered up for the then rookie, but examinations may have revealed that the tear was less severe than three seasons ago. The pass rusher has totaled 10 sacks the past two campaigns, while logging 66 and 58.5 percent of the defensive snaps, but the addition of Chandler Jones along with the injury could very well result in a scaled-back role.
Brown won't practice Wednesday due to a headache, Darren Urban of the Cardinals' official site reports.
Concussions are not to be trifled with, and Brown's case is exhibit A. On Sunday, he was cleared for practice, but his early departure didn't raise any particular concern. Donning a yellow no-contact jersey both Sunday and Monday wasn't out of the ordinary, either, as players can participate in certain drills depending upon their current stage in the NFL's protocol for head injuries. With clear symptoms lingering, questions can now be raised regarding his availability as Week 1 approaches. If DNPs come to pass, both Jaron Brown and JJ Nelson would receive bumps in relevance.
Jenkins (hand) returned to practice on Sunday, Mike Jurecki of Fox Sports 910 reports.
Jenkins had surgery for a broken hand at the start of August. He was expected to miss anywhere from 2-to-3 weeks, so his return Sunday appears to be on the early side of that original projection. Jenkins will have to battle for a role as a depth option at cornerback for the upcoming season.
Wentz (ribs) will not play in Saturday's matchup with the Colts.
Wentz suffered a hairline rib fracture in the preseason opener and hasn't taken the field since. His final chance to return will be on Sept. 1 in the final preseason game against the Jets. With Wentz out, Sam Bradford has cemented his role as the Eagles' starting quarterback this preseason and should see a majority of the reps on Saturday night.
Matthews, who suffered a bone bruise on his left knee back on Aug. 5, plans to be ready to play in advance of Week 1, the Philadelphia Inquirer reports. "I promise you I'll be ready for the first game," Matthews declared Tuesday. "I don't like to put percentages on anything, but at the same time, I'm definitely feeling good. I'm doing a lot better. I'm running around, moving, lifting, jumping. I'm back doing pretty much all of that stuff."
Matthews, who is coming off a 2015 campaign in which he caught 85 passes for 997 yards and eight touchdowns, doesn't seem likely to see any preseason action, but the goal here is exercise a degree of patience and caution, with having the wideout available for the Eagles' Sept. 11 contest against the Browns. Upon his return to action, Matthews is set to serve as the team's top wideout, with Nelson Agholor, Dorial Green-Beckham, Rueben Randle, Josh Huff, Chris Givens and Paul Turner all still jostling for slotting on Philadelphia's wideout depth chart.
Smallwood (quadriceps) is slated to take the field for Saturday's preseason game at Indianapolis, Jeff McLane of the Philadelphia Inquirer reports.
Smallwood missed back-to-back contests to kick off exhibition season, but increasing his workload little by little for two weeks will seemingly yield an appearance Saturday. A cautious approach is expected, though, as the running back's quad continues to heal. All but guaranteed a roster spot due to his status as a 2016 fifth-round selection, he could be relegated to weekly inactives in-season with Ryan Mathews, Darren Sproles, and Kenjon Barner all positioned ahead of Smallwood on the depth chart.