Tom Brady is 2-5 in games at Denver and the Patriots' offense is running low on offensive weapons. Can they keep the streak going? Three teams that look playoff worthy? The Seahawks, Texans and ... Bucs.
Can Big Ben and the Steelers keep pace with the division-leading Bengals? They'll have to get past the Seahawks -- in Seattle. Will Brock Osweiler give the Broncos a fighting chance against the 10-0 Patriots?
Brown (hamstring) is listed as probable for Sunday's game against the 49ers, CSN Bay Area reports.
Brown may still be somewhat bothered by his hamstring, but the injury didn't stop him from playing a full complement of snaps in Week 11 against the Bengals. He could, however, lose a few of those snaps to Michael Floyd (hamstring), who is listed as questionable for Sunday's game in San Francisco.
Bucannon (concussion) is listed as questionable for Sunday's game in San Francisco, CSN Bay Area reports.
According to Darren Urban of the Cardinals' official website, head coach Bruce Arians said the team will be careful with Bucannon, who probably won't be needed in this matchup. There's still some chance the safety/linebacker suits up, but it sounds as if the Cardinals are more inclined to wait a week.
Cardinals defensive end Calais Campbell was a one-man wrecking crew Sunday against the Rams, racking up 11 tackles (10 solo), three tackles for loss, two quarterback hits, and 0.5 sacks.
Campbell was everywhere in Week 4, but the Cardinals' defense itself was unable to force a turnover, after accumulating seven (all interceptions) over the course of the first three weeks of the season. Stuck in the 50-to-75 tackle territory in each of the past five campaigns, he currently has 25 to his credit, which is a career-best pace. On the other side of the coin, the half sack Sunday was his first in the category in 2015, so he has some work to do to uphold his standard (6-to-9 sacks in six consecutive seasons).
Fitzgerald (ankle) is listed as probable for Sunday's game in San Francisco, CSN Bay Area reports.
Fitzgerald returned to a full practice Friday, following limited sessions Wednesday and Thursday. He'll square off against one of the NFL's worst defensive backfields, but the matchup may lead to a heavy dose of Arizona's Chris Johnson-led running game.
Floyd (hamstring) is listed as questionable for Sunday's game in San Francisco, CSN Bay Area reports.
A limited participant throughout the week of practice, Floyd should be available for Sunday's game, according to Darren Urban of the team's official website. However, Floyd seems to be the least healthy of Arizona's three main wide receivers, and the matchup probably won't require high volume from the passing game. Assuming he suits up and doesn't suffer a setback, Floyd will be a much more attractive option in Week 13 against the Rams.
Johnson (knee) is listed as probable for Sunday's game in San Francisco, CSN Bay Area reports.
Following limited sessions Wednesday and Thursday, Johnson logged a full practice Friday. He should be cleared for his usual workload against a 49ers defense that he ripped for 22-110-2 back in Week 3.
Peterson (ankle) is listed as questionable for Sunday's game in San Francisco, CSN Bay Area reports.
According to Darren Urban of the Cardinals' official website, head coach Bruce Arians said Friday that he expects Peterson to play in Sunday's game. The star cornerback missed practice Wednesday and Thursday, but he then returned as a limited participant Friday morning. There is some chance Peterson will be active but play fewer snaps than usual.
Boldin (hamstring) hauled in five of seven targets for 93 yards in Sunday's 29-13 loss at Seattle.
It was a brutal matchup for Boldin and he didn't appear to be 100 percent, looking gimpy on some routes. He also spent a little time on the bench in the first half, while the 49ers had the ball, warming up his tender hamstring. However, he made a number of tough grabs in traffic, and seemed to have a solid rapport with Blaine Gabbert, who did a nice job in the loss, completing 22 of 34 passes for 264 yards and a touchdown. Assuming Boldin made it out of Sunday's game without any setback, he'll have another tough matchup in Week 12 against the Cardinals.
Bowman (shoulder) had a relatively quiet game by his standards, recording nine tackles (four solo) in the 29-13 loss to the Seahawks.
Bowman continues to pop up on the injury report for a minor shoulder injury, but it didn't seem to affect the veteran linebacker as he was on the field for all 78 of the team's defensive snaps. With the opposition running the ball 44 times, you would think Bowman would have notched more than nine tackles, but Thomas Rawls was getting into the secondary consistently which did not benefit Bowman. A matchup against the Cardinals' potent air attack looms next week, so the tackle totals could be held in check for Bowman yet again.
Brooks (personal) returned to the field Thursday, recording five tackles (two solo) and a pair of sacks in the loss to Seattle.
Brooks had missed last week's contest to attend the funeral of his sister. He returned Thursday and the extra rest seemed to have given the veteran linebacker a boost. While this was a monster game, it has to be taken with a grain of salt, as the Seattle offensive line is, well, offensive.
Hyde (foot) has been ruled out for Sunday's game against the Cardinals, CSN Bay Area reports.
Hyde still hasn't played since Week 7 and is no lock to suit up again this season. Shaun Draughn will continue to lead the San Francisco backfield, with Kendall Gaskins and Travaris Cadet working in reserve. Draughn played nearly all of the offensive snaps in Week 11 against the Seahawks.
Antoine Bethea is set to start for the 49ers this season at strong safety with Eric Reid entrenched at free safety. But the former doesn't know who their secondary mates will be and he's expecting quite a battle.
Tartt finished with eight tackles (four solo) in Sunday's loss to Seattle.
Tartt has been starting at strong safety ever since Antoine Bethea (shoulder) was shut down for the season. He has been averaging 6.0 tackles in the those three starts. He doesn't seem like the type of player that will haul in too many interceptions, but his size and athleticism give him a little upside in IDP leagues for tackles, forced fumbles, and the occasional sack.
Smelter (knee) is slated to practice this week, the San Jose Mercury News reports.
Smelter will remain on the 49ers' Reserve/Non-Football Injury list for now, as the team has a three-week window in which to evaluate whether or not to officially add the wideout to the team's 53-man active roster.