It was initially thought that Holmes suffered a significant injury, but it wasn't clear what exactly the issue was. Now that it's clear he suffered a severe high ankle sprain, coach Jack Del Rio said Holmes will likely end up on season ending injured reserve. Look for Ryan O'Malley and Colton Underwood to see some extra reps with Holmes out.
Holmes is dealing with a "significant" ankle injury and could miss the 2016 season, Jimmy Durkin of the Bay Area News Group reports.
Holmes was signed to the Raiders' active roster late during the 2015 season, and has been battling throughout training camp for another spot on the squad. The ankle injury presents a setback for the 25-year-old Purdue product, as he could be headed for the season-ending injured reserve. An update on his status should become available upon further testing, while his potential absence shouldn't have much of a fantasy impact with Lee Smith, Clive Walford (knee), and Mychal Rivera leading the way at tight end.