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| All times are US/Eastern | Buy NFL Tickets |
| WEEK 1 | ||
| Wednesday, Sep. 05 | ||
| Game | Time | TV |
| Dallas at N.Y. Giants | NBC | |
| Sunday, Sep. 09 | ||
| Game | Time | TV |
| Indianapolis at Chicago | CBS | |
| New England at Tennessee | CBS | |
| Buffalo at N.Y. Jets | CBS | |
| Washington at New Orleans | FOX | |
| Jacksonville at Minnesota | CBS | |
| Atlanta at Kansas City | FOX | |
| Philadelphia at Cleveland | FOX | |
| St. Louis at Detroit | FOX | |
| Miami at Houston | CBS | |
| San Francisco at Green Bay | FOX | |
| Seattle at Arizona | FOX | |
| Carolina at Tampa Bay | FOX | |
| Pittsburgh at Denver | NBC | |
| Monday, Sep. 10 | ||
| Game | Time | TV |
| Cincinnati at Baltimore | ESPN | |
| San Diego at Oakland | ESPN | |
