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| All times are US/Eastern | Buy NFL Tickets |
| WEEK 2 | ||
| Thursday, Sep. 13 | ||
| Game | Time | TV |
| Chicago at Green Bay | NFL Network | |
| Sunday, Sep. 16 | ||
| Game | Time | TV |
| Kansas City at Buffalo | CBS | |
| Baltimore at Philadelphia | CBS | |
| Tampa Bay at N.Y. Giants | FOX | |
| Arizona at New England | FOX | |
| Houston at Jacksonville | CBS | |
| Minnesota at Indianapolis | FOX | |
| Cleveland at Cincinnati | CBS | |
| New Orleans at Carolina | FOX | |
| Washington at St. Louis | FOX | |
| Dallas at Seattle | FOX | |
| Tennessee at San Diego | CBS | |
| N.Y. Jets at Pittsburgh | CBS | |
| Oakland at Miami | CBS | |
| Detroit at San Francisco | NBC | |
| Monday, Sep. 17 | ||
| Game | Time | TV |
| Denver at Atlanta | ESPN | |
