| Interceptions | ||||||||||||||||
| Interceptions | Fumbles | Tackles | Other | |||||||||||||
| Player | Pos | Team | G | Int | Yds | LG | TD | FF | Rec | TD | Cmb | Solo | Ast | Sack | Pdef | Sfty |
| Sam Shields | CB | GB | 2 | 2 | 52 | 52 | 1 | 0 | 0 | 0 | 11 | 9 | 2 | 0 | 6 | 0 |
| Cary Williams | CB | BAL | 4 | 2 | 41 | 41 | 0 | 0 | 0 | 0 | 27 | 21 | 6 | 0 | 8 | 0 |
| Corey Graham | CB | BAL | 4 | 2 | 39 | 39 | 1 | 0 | 0 | 0 | 32 | 20 | 12 | 0.5 | 9 | 0 |
| Tarell Brown | CB | SF | 3 | 1 | 39 | 39 | 0 | 1 | 1 | 0 | 12 | 11 | 1 | 0 | 4 | 0 |
| Leon Hall | CB | CIN | 1 | 1 | 21 | 21 | 1 | 0 | 0 | 0 | 4 | 4 | 0 | 0 | 2 | 0 |
| Johnathan Joseph | CB | HOU | 2 | 1 | 14 | 14 | 0 | 0 | 0 | 0 | 10 | 8 | 2 | 0 | 3 | 0 |
| Chris Culliver | DB | SF | 3 | 1 | 6 | 6 | 0 | 0 | 0 | 0 | 13 | 12 | 1 | 0 | 4 | 1 |
| Ed Reed | FS | BAL | 4 | 1 | 6 | 6 | 0 | 0 | 0 | 0 | 15 | 14 | 1 | 0 | 4 | 0 |
| Rob Ninkovich | DE | NE | 2 | 1 | 6 | 6 | 0 | 0 | 0 | 0 | 12 | 6 | 6 | 2.0 | 3 | 0 |
| Bobby Wagner | MLB | SEA | 2 | 1 | 4 | 4 | 0 | 0 | 0 | 0 | 17 | 12 | 5 | 0 | 2 | 0 |
| Dannell Ellerbe | ILB | BAL | 4 | 1 | 2 | 2 | 0 | 0 | 0 | 0 | 32 | 25 | 7 | 0 | 3 | 0 |
| Earl Thomas | FS | SEA | 2 | 2 | 1 | 2 | 0 | 0 | 0 | 0 | 8 | 3 | 5 | 0 | 4 | 0 |
| Julio Jones | WR | ATL | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 |
