Channing Crowder, LB, Dolphins: This, of course, is not a surprise, but Miami will miss him on the inside of its 3-4 defense. Look for Tim Dobbins to get his playing time, but he's also gotten plenty of work in the preseason with Crowder's absence.
Michael Bush, RB, Raiders: Darren McFadden will start, and that actually might not be the worst thing in the world for QB Jason Campbell. You have to like McFadden's veteran leadership, and he might actually provide some relief for Campbell.
Julian Edelman, WR, Patriots: He was questionable coming into today's game, and with no one sure how Wes Welker will perform for a full game, losing your No. 3 WR is a tough blow against a Bengals secondary that will be tough. But look for rookie TE Aaron Hernandez to benefit.
Brian Leonard, RB, Bengals: Unless you watch Cincinnati every week, you won't understand how big a blow this is for the Bengals. You'll be hard-pressed to find a better RB in the league at converting on third downs.
Brady Quinn, QB, Broncos: He's the emergency No. 3 QB, and though this move is relatively insignificant, it just confirms that Tim Tebow is officially the backup to Kyle Orton.
Aaron Ross, CB, NYG -- Ross is out with a "foot," as many an announcer would say. More accurate is probably "plantar faciitis," which makes this unsurprising.
LeGarrette Blount, RB, TB -- It's not shocking to see Blount out, it just means that we don't get to use the phrase "he's got a puncher's chance of playing today!" And that's highly disappointing, obviously.
Jeff Otah, OL, CAR -- It was presumed that Otah wouldn't be playing during today's game, but it's still a big blow for a Panthers team that is going to depend heavily on the run today against the Giants.
Armanti Edwards, WR, CAR -- The Panthers burned an early pick on Edwards. Thus far, he hasn't exactly justified the investment. Captain Munnerlyn and Mike Goodson will handle kickoff duties.
Victor Cruz, WR, NYG -- NOOO. Everyone's favorite preseason hero (he blew up during the Giants first game against the Jets) won't be playing today.
Kevin Smith, RB, DET -- Smith was dangerously close to getting cut by the Lions and while he's on the team, if Jahvid Best blows up early for Detroit, he's not going to earn any more playing time by sitting the game out.
Matt Leinart, QB, Texans: You surprised?
Ikaika Alama-Francis, LB, Dolphins: This is a bit of a surprise, because he had been battling with rookie Koa Misi for the starting spot. There had been some concerns about Misi's ability to hold the corner on running plays.
Brian Brohm, QB, Bills: After a preseason QB battle with Trent Edwards and Ryan Fitzpatrick, Brohm is officially the No. 3 behind starter Edwards and backup Fitzpatrick.
Demaryius Thomas, WR, Broncos: Thomas is battling a foot injury, but this is disappointing for the first of Denver's first-round picks. Thomas practiced all week, but apparently, he's not ready to play.